The brain energy deficit in Alzheimer's «can at least in part be bypassed by ketogenic treatments.
We suggest that
the brain energy deficit needs to be overcome in order to successfully develop more effective therapeutics for AD.
We propose that
brain energy deficit is an important pre-symptomatic feature of Alzheimer's disease (AD) that requires closer attention in the development of AD therapeutics.
Not exact matches
The restoration also takes an enormous amount of
energy — more than the injured
brain can provide — and so creates an «
energy crisis,» or
energy deficit in the
brain.
The biggest concern surrounding concussions comes from the
energy deficit that occurs in the
brain following injury.
Some of these factors can impair mitochondrial function10, and increasing evidence points to an
energy deficit as a major feature of the
brain and spinal cord in multiple sclerosis (MS) e.g. refs 11, 12, 13, 14, 15 implicating an
energy deficit in the pathophysiology of the functional
deficit.
A sustained
energy deficit causes a reduction in visceral fat which improves the function of the heart, liver, pancreas and
brain.