Sentences with phrase «brain parenchyma»

In contrast, a recent study has showed that there is evidence of increased volume of brain parenchyma within the CCF in CKCS with syringomyelia compared to CKCS without syringomyelia [19].

This has been attributed to high - velocity jets of CSF caused by obstruction of the foramen magnum by the herniated portion of the cerebellum and overcrowded brain parenchyma in the caudal occipital region [5] which is hypothesised to set up a hydrostatic pressure differential between the spinal cord and subarachnoid space and results in the accumulation of perivascular fluid which eventually forms a syrinx [9].

CCF, cranial cranial fossa, and brain parenchyma volumes of all SB and LD individuals and 42 CKCS were used in a previous study [18].

This finding is consistent with previous research, which has shown that CKCS possess a CCF parenchyma proportionately similar in volume to that of a Labrador and a CCF volume similar to small breed dogs, suggesting that CCF growth in CKCS is not keeping pace with the growth of brain parenchyma [18].

It has been proposed that the volume mismatch between the CCF and brain parenchyma in CKCS can be explained by impaired occipital bone development and the consequent reduction in CCF volume [5], [16], [21].

CM in CKCS is the manifestation of cerebellar herniation through the foramen magnum, and previous studies have shown that this is associated with increased crowding of brain parenchyma within the CCF [18], [19].

CCF, cranial cranial fossa and brain parenchyma volumes of 49 CKCS individuals were used in another study [19].

«In contrast, in age - matched fetuses from germ - free mothers, these labeled antibodies easily crossed the blood - brain barrier and was detected within the brain parenchyma.»

«We showed that the presence of the maternal gut microbiota during late pregnancy blocked the passage of labeled antibodies from the circulation into the brain parenchyma of the growing fetus,» says first author Dr. Viorica Braniste at the Department of Microbiology, Tumor and Cell Biology at Karolinska Institutet.

Furthermore, the CSF detection of Aβ peptides suggest a dynamic state of these molecules, where some accumulate inside neurons, and some are exported to the extracellular space, from where they can reach the CSF even in the absence of amyloid plaques in the brain parenchyma.

Brains were transferred to 2.5 mL cold RPMI medium 1640 + L - glutamine (Sigma) and meninges were dissected from the skullcaps as described elsewhere [38] and combined with the brain parenchyma.

Iliff JJ, Wang M, Liao Y, Plogg BA, Peng W, Gundersen GA, Benveniste H, Vates GE, Deane R, Goldman SA, Nagelhus EA, Nedergaard M A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β Sci Transl Med, 4:147 ra111

Note the bone fragment (single arrow) that is within the brain parenchyma.

Canine Chiari - like malformation (CM) is a complex abnormality characterized by overcrowding of the craniocervical junction and by disparity in size between the brain parenchyma (too big) and the skull (too small)[1].

Previous research in Cavalier King Charles Spaniels (CKCS) has found that Chiari - like malformation and syringomyelia (CM / SM) are associated with a volume mismatch between the caudal cranial fossa (CCF) and the brain parenchyma contained within.

Image threshold was set to zero and contrast altered to include all brain parenchyma.

Generalised overgrowth of brain parenchyma (megalencephaly) is recognised in over 100 human syndromes [27] and in some of these conditions posterior cranial fossa overcrowding and herniation of the cerebellum have been reported.

Relative cerebellar volume was defined as the volume of the cerebellum divided by the total volume of brain parenchyma.