Sentences with phrase «brain samples of»

Observations of reactive microglia in postmortem brain samples of PD patients had led to suggestions that microglia are involved in the neuropathological changes in DA neurons that are inherent to this disease.»
He also has a network of dozens of paraveterinary assistants in surrounding villages who keep an ear out for reports of rabid dogs, conduct interviews, and, when possible, take brain samples of dogs suspected to have died of rabies.
Recent studies have found elevated levels of this protein in post-mortem brain samples of patients with MS.. In this latest work, investigators compared the frequencies of «more active» and «less active» variants of the DNA sequences that control expression of the galanin gene between healthy controls and MS patients.
They injected the molecules into mice to create antibodies capable of recognizing the various suspect proteins, and then searched through the antibodies to find those that stuck only to the clumps in brain samples of FTD patients.
To identify the mystery molecule, neurobiologists Virginia Lee and John Trojanowski of the University of Pennsylvania and their colleagues isolated a group of proteins from brain samples of people with FTD.
In addition, the researchers looked at brain samples of deceased patients with MS and found increased numbers of GM - CSF - producing cells in comparison to normal brain samples.
The Raman images now show protein activity at neural cell level, but the sensitivity is high enough for detecting areas that are even smaller — as is the case with the brain sample of the healthy person.

Not exact matches

After taking samples and conducting brain scans, the researchers found that 41 percent of mothers of babies with microcephaly tested positive for Zika infection in blood or cerebrospinal fluid samples, compared with none of those whose babies did not have microcephaly.
Maja Pantic, a professor of affective and behavioral computing at Imperial College in London, tells Sample she is worried about a one - way brain drain from schools to tech companies:
Days after the report was released, the NFL released an official statement acknowledging the findings, but also suggesting that they may not be representative of all of the league's players: «The report doesn't confirm that the condition is common in all football players; it reflects high occurrence in samples at the Boston brain bank that studies CTE,» they wrote.
I totally have pesto on the brain after recently giving out samples of one of my pesto recipes with The Foodstand at a local famers»...
Researchers looked at 133 babies using specialized, «baby - friendly» magnetic resonance imaging to analyze brain growth in a sample of children under the age of 4.
In 2007, researchers published the first randomized, controlled study of the effect of being raised in an orphanage; that study, and subsequent research on the same sample of Romanian orphans, found that compared with babies placed with a foster family, those who were sent to institutions had lower IQs, slower physical growth, problems with human attachment and differences in functioning in brain areas related to emotional development.
«For the first time, we have found that a sample of randomly assigned young adults showed less activation in certain frontal brain regions following a week of playing violent video games at home,» said one researcher.
More work has to be done on humans as many of the results showed up in mice samples, however in studying the human brains of women who had AD scientists found significantly less male fetal tissue in their brains as in the same of women who did not have AD.
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.
Huntington's disease and other inherited brain conditions are challenging to study because it is difficult to obtain samples of neurons from living patients.
Endocast researchers need to study the range of brain surface characteristics in a larger sample of living chimps and other apes to make more accurate comparisons, Falk says.
A team led by geneticist Steven McCarroll of the Broad Institute, based in Cambridge, Mass., combed through genetic information from about 29,000 schizophrenia cases, 36,000 controls and 700 brain samples from deceased patients.
Examinations of NFL players» postmortem brains turned up chronic traumatic encephalopathy in 99 percent of samples in large dataset.
The search for more of these factors is complicated by the rarity of brain samples from suicide victims and the lack of an animal model — humans are unique in their wilful ability to end their lives.
A majority of football players whose brains were donated for research suffered a degenerative brain disease during their lives, according to the largest sample of players ever studied.
Whereas analyses of the brain were once limited to autopsy samples at the time of a person's death, advances in an imaging technique known as positron emission tomography (PET) now enable researchers to detect amyloid and tau in the brains of living people.
He and his colleagues analyzed brain scans and blood samples from a group of 121 Japanese patients and a group of 252 Australian patients.
For a study published with Kuhnlein in 2002, Fediuk compared the vitamin C content of 100 - gram (3.55 - ounce) samples of foods eaten by Inuit women living in the Canadian Arctic: Raw caribou liver supplied almost 24 milligrams, seal brain close to 15 milligrams, and raw kelp more than 28 milligrams.
HBI member V. Wee Yong, PhD and research associate Susobhan Sarkar, PhD, and their team including researchers from the Department of Clinical Neurosciences and the university's Southern Alberta Cancer Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are compromised.
Alzheimer's mice with normal BACE1 levels experienced a steady increase in plaques, clearly seen in samples of their brains.
To try to pin down its role, McCarley and his team first tracked the levels of adenosine by extracting samples of brain fluid from cats throughout normal sleep - wake cycles.
The scientists compared that tissue with brain tissue samples from three young amateur American football players and a professional wrestler, all of whom had a history of repetitive concussive injury, and with four samples from comparably aged control subjects with no history of blast exposure, concussive injury or neurological disease.
At Cox's urging, Mash set out to conduct an independent study of ALS and Alzheimer's brains using samples from her own human brain bank.
Dr Brastianos will say: «When brain metastasis tissue is available as part of clinical care, we are suggesting sequencing and analysis of that sample.
One of the limits of the study, he said, was that his team could only assess the presence of antibodies in a blood sample, not a brain fluid sample.
The end sample of 1,162 brains was a bit more diverse than the U.S. population.
Even a large sample may not provide an accurate picture of brain development — if that sample has biases of its own.
They applied sample weights to the brain imaging data, giving more weight to the brains of kids with poorer, less educated families, and adding additional weights to match the racial demographics of the United States.
Of course, it is generally not possible to sample the brains of living peoplOf course, it is generally not possible to sample the brains of living peoplof living people.
Ronald Kahn and his colleagues at Harvard Medical School in Boston compared gene expression in brain samples from mice with type 1 or type 2 diabetes against those of healthy mice.
Many of the families who donated the brains for research could have been motivated to do so because their loved ones had noticeable symptoms, so the sample is not necessarily representative of the general football population.
The researchers tested samples of brain cells from people with MS and healthy control subjects and found evidence of the virus in the olfactory bulb in both groups.
Working with an international group of scientists from Cardiff University, Stanford University and Duke University in addition to screening post-mortem brain samples from the Stanley Medical Research Institute, the scientists are the first to identify a molecular genetic component of the blood brain barrier with the development of schizophrenia.
These samples were collected primarily by Gianluigi Zanusso, M.D., Ph.D., and colleagues at the University of Verona in Italy, who developed the technique of brushing the inside of the nose to collect olfactory neurons connected to the brain.
What's more, they added, the sample is heavily weighted to men who played football in college or professionally, exposing them to far more hits to their heads than those who played only on youth or high school teams: These younger players accounted for only 16 brains in the sample of 202.
Ron Duman and colleagues at Yale University began their search for a mechanism behind depression by comparing post-mortem brain samples from 21 people who had been depressed and 18 people of the same age.
Their samples came from the liver, spleen, brain and heart of 11 cadavers, between 20 and 240 hours after death.
The team looked for these cells in nonliving brain samples in two ways: molecular markers that tag dividing cells and young nerve cells, and telltale shapes of newborn cells.
Accumulation of insoluble U1 protein was seen in samples from patients with mild cognitive impairment (MCI), a precursor stage to Alzheimer's, but the U1 pathology was not seen in any other brain diseases that were examined.
In comparison to RNA from healthy brains, more of the RNA from Alzheimer's brain samples was unspliced.
The strength of the paper, he says, is that the large number of animals involved provide a good sample of the different ways in which chimp brains age.
Working in Morrison's Neurotrauma and Repair Laboratory at Columbia Engineering, the team developed a blast injury model using a shock tube and custom - designed sample receiver to simulate a primary blast event and applied it to an isolated, living model of the BBB that consisted of brain endothelial cells.
The study divides 177 blood and 27 post-mortem brain samples into several groups, establishing that careful analysis of RNA transcripts in blood samples has the ability to distinguish early clinical AD, Parkinson's disease (PD), and cognitively healthy patients.
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