These findings were confirmed by two - photon imaging of neurons in the brains of living mice by the lab of collaborator Yi Zuo, PhD, a neuroscientist at UC Santa Cruz, as well as electrophysiological recordings from neurons in
brain slices by the lab of collaborator Vikaas Sohal, MD, PhD, an associate professor of psychiatry at UCSF.
Studies of individual neurons in dishes of cultured neurons and in
brain slices by co-first author Robert E. Stanley, a graduate student in the lab, revealed that neurons in the mutant mice had decreased numbers of dendritic spines, an important part of the synapses that neurons use to communicate with one another.
Not exact matches
A Toronto - based company hopes to capture a
slice of the $ 1 - billion
brain fitness market
by helping baby boomers answer that question.
We then did a drive -
by of Pizza
Brain (a
slice shop / pizza memorabilia museum that Tony helped open a few years ago; he's immortalized in a backyard mural)[Amiel: What, you're not going to mention the Last Supper — style oil painting of my friends and me that's hanging at 12 Steps Down?]
Indeed,
by examining
brain tissue and
slices from the cocaine - addicted rats at various stages of withdrawal and craving, Wolf and her colleagues discovered that the incubation period and the subsequent spike in craving appeared to correlate with the appearance of atypical AMPA receptors on the surface of neurons in the NAc, which could help explain cocaine craving.
The team decided to verify that finding
by treating tissue
slices from developing ferret
brains with a chemical that blocks BDNF's activity.
In this study, the researchers from Imperial's Department of Surgery and Cancer and the Royal British Legion Centre for Blast Injury Studies, applied xenon to
slices of mouse
brain tissue after exposing them to blast shockwaves that emulated those produced
by improvised explosive devices (IEDs).
By using a dye that highlights damaged
brain cells, they were able to monitor injury development in the
slices up to three days after blast exposure.
The
slices of
brain will be turned into digital images
by an automated electron microscope.
Using electron microscopy to look at thousands of ultrathin
brain slices taken from awake and sleeping mice, they found that after sleep, the size of most synapses — specifically, the surface area where two neurons touch each other — shrank
by about 18 percent.
The mouse atlas was produced using a method called «in situ hybridisation», in which thin
slices of
brain tissue are bathed in a solution containing molecular probes that bind to messenger RNA sequences produced
by each gene.
This
brain slice from a human autopsy has taken on vivid color in the hands of a neuroscientist: green from infection
by a lentivirus, red for neurons, blue for the nuclei of
brain cells.
It was created
by embedding a 65 - year - old woman's
brain in wax, before
slicing it into more than 7400 sections and imaging it (Science, doi.org/m3b).
Where else at CES could you see a two -
by - two grid of higher - than - HD - quality monitors display a rotating 3 - D image of a skyscraper, folded protein or
brain slice?
In the lab, researchers chart each neuron
by tracing its thousands of projections through stacks of hundreds of overlapping
brain -
slice images.
Long - term goal of the project will be to visualize and manipulate tau expression also in a systemic context (organotypic
slice preparations, mouse
brain)
by affecting the function of tau mRNA - containing neuronal granules as a potential drug target for the treatment of neurodegenerative diseases.
In a paper in the Proceedings of the National Academy of Sciences, a research team led
by Carlo Condello presented their results from a study of the
sliced brain fragments of deceased Alzheimer's disease (AD) patients.
By intracellular and whole cell recording in rat
brain slices, it was found that bath - applied serotonin (5 - HT) produces an increase in the frequency and amplitude of spontaneous excitatory
Li Gan, PhD, hopes to use the microscope to image firing cells in live
brain slices, while Leor Weinberger, PhD, is interested in studying the processes
by which a virus enters a cell in real time.
«Schumer redeems I Feel Pretty
by completely and fearlessly buying into the premise, and delivering a few good lines that
slice into the shallow idiocy of valuing beauty over
brains and celebrities over common folk» — Peter Howell, The Toronto Star
By then, Alzheimer had moved from Frankfurt to the Royal Psychiatric Clinic in Munich, so he had Auguste's
brain sent there, where he «sampled thin
slices of this
brain tissue, [and] stained them with silver salts.»
The story is simple: after being overrun
by brain - crazed zombies, a small town is rapidly locked down tight
by the military and now you are forced to
slice, dice and shoot your way through the hordes of zombies that stand in your way.