Sentences with phrase «brain slices from»

In general, it has been difficult to preserve electrophysiologically viable motoneurons in brain slices from adult mammals.

And those same Abs would have to detect intracellular and axonal SN aggregates present in brain slices from synucleinopathic mice, but not to neurons from WT mice in vivo.

When the team compared brain slices from the two groups of rats, they discovered that in the intact animals, more CREB molecules carried a phosphate group — a crucial step for their activation.

Hu's team then took brain slices from the mice in order to measure the electrical currents produced from mPFC neurons.

Then they prepared mouse brain slices from a group of neurons in the dopamine production center, at 24 hours and every day thereafter.

To analyze the rats» brains, the team extracted brain slices from depressed and normal animals, soaked them in voltage - sensitive dye, and prodded them with electrodes next to a high - speed camera.

So Yang Shi and her PhD advisor, neurologist David Holtzman at Washington University were in for a surprise when they peeked at a set of brain slices from mice engineered to produce tau pathology.

Annese holds a whole - brain slice from another amnesic patient.

This brain slice from a human autopsy has taken on vivid color in the hands of a neuroscientist: green from infection by a lentivirus, red for neurons, blue for the nuclei of brain cells.

Not exact matches

Indeed, by examining brain tissue and slices from the cocaine - addicted rats at various stages of withdrawal and craving, Wolf and her colleagues discovered that the incubation period and the subsequent spike in craving appeared to correlate with the appearance of atypical AMPA receptors on the surface of neurons in the NAc, which could help explain cocaine craving.

To figure out how the neurotrophins might shape the brain, Kimberly McAllister, Lawrence Katz, and Donald Lo, all at Duke University, examined the effects of two of them, brain - derived neurotrophic factor (BDNF) and neurotrophin - 3 (NT - 3), on slices of the cerebral cortex from the developing brains of young ferrets.

The team decided to verify that finding by treating tissue slices from developing ferret brains with a chemical that blocks BDNF's activity.

My project was in neuroscience, working on a model of epilepsy using electrophysiological recordings from brain slices.

In this study, the researchers from Imperial's Department of Surgery and Cancer and the Royal British Legion Centre for Blast Injury Studies, applied xenon to slices of mouse brain tissue after exposing them to blast shockwaves that emulated those produced by improvised explosive devices (IEDs).

The brain images Brewer shows me — views from the side, back, and top — look like a cross between a nice, fat slice of sausage and a Rorschach inkblot test.

These findings were confirmed by two - photon imaging of neurons in the brains of living mice by the lab of collaborator Yi Zuo, PhD, a neuroscientist at UC Santa Cruz, as well as electrophysiological recordings from neurons in brain slices by the lab of collaborator Vikaas Sohal, MD, PhD, an associate professor of psychiatry at UCSF.

In this picture, H. M.'s brain is being sliced in a plane roughly parallel to the face, in the same orientation as an image from a typical brain scan.

Using electron microscopy to look at thousands of ultrathin brain slices taken from awake and sleeping mice, they found that after sleep, the size of most synapses — specifically, the surface area where two neurons touch each other — shrank by about 18 percent.

Digging for the root of the problem, the team experimented with slices of brain from the mutant mice.

Next, Südhof's team examined slices of brain tissue from the mutant mice.

They're planning to thin - slice a brain and trace each neural pathway from slice to slice, creating a map of the brain and a way to visualize how the mind works.

Another Kavli researcher, Steven Siegelbaum, uses a technology called two - photon microscopy to image pre-synaptic terminals (the nerve cell tips that send charges from one cell to another) within slices of living brain tissue.

In order to characterize this possible imbalance, we performed in vitro brain slice whole patch - clamp recordings from the Q175 heterozygous knock - in HD mouse model expressing GFP under the control of the D2 receptor promoter to identify dSPNs (GFP - negative) and iSPNs (GFP - positive).

Chen Gu and his team obtained slices of brain tissue from dead mice.

She suggests coloring different parts of brain slices (from dead people) using specific dyes and viewing them under a microscope.

In a paper in the Proceedings of the National Academy of Sciences, a research team led by Carlo Condello presented their results from a study of the sliced brain fragments of deceased Alzheimer's disease (AD) patients.

A Bright Bunch: These images, from a 2005 study in Cognitive Brain Research, show horizontal slices in the brains of adolescent boys, as measured while they were doing a spatial math problem.

By then, Alzheimer had moved from Frankfurt to the Royal Psychiatric Clinic in Munich, so he had Auguste's brain sent there, where he «sampled thin slices of this brain tissue, [and] stained them with silver salts.»

But when you've had children with someone you're divorced from, divorce defines everything; it's the lurking fact, a slice of anger in the pie of your brain.