From these correlations, the investigators were able to create a map of connections from deep
brain stimulation sites to the surface of the brain.
Not exact matches
They next listed the
stimulation sites, either deep in the
brain or on the surface of the
brain, thought to be effective for the treatment of each of the 14 diseases.
Divided into two broad approaches, invasive and noninvasive,
brain stimulation works by targeting specific
sites to adjust
brain activity.
Led by investigators at Beth Israel Deaconess Medical Center (BIDMC), the findings suggest that
brain networks — the interconnected pathways that link
brain circuits to one another — can help guide
site selection for
brain stimulation therapies.
However, getting this same benefit with noninvasive
stimulation is difficult, as you can't directly stimulate the same
site deep in the
brain from outside the head,» explains Fox, an Assistant Professor of Neurology at Harvard Medical School (HMS).
«We wanted to test the hypothesis that these various
stimulation sites are actually different spots within the same
brain network,» explains Fox.
However, it has been established that the ability of deep -
brain stimulation to modify
brain functions depends on the application of
stimulation at specific
sites in the complex neuronal circuitry underlying these functions.2 - 5
Depending on
stimulation parameters (frequency, intensity, pulse duration,
stimulation site), repetitive TMS (rTMS) to specific cortical regions can either increase or decrease the excitability of the affected
brain structures.
This technology delivers a consistent stream of electrical
stimulation to an implantation
site located deep in the
brain; however, because
stimulation is always on, the DBS's battery may deplete quickly, which necessitates invasive surgery for replacement.
The
site's games are a major standout, mirroring Luminosity's
brain -
stimulation games.