Sentences with phrase «brain tissue from»

Increased reactive oxygen species (ROS) levels have been observed in post-mortem brain tissue from patients with neurodegenerative disorders, including [9]:

When brain tissue from mice affected by Alzheimer's was with treated with vitamin C, the toxic protein aggregates had been dissolved.

It's known, for example, that taking brain tissue from a mouse with Alzheimer's disease and injecting it into healthy mice will cause the latter to develop the neurodegenerative disease.

Her team examined autopsied brain tissue from 28 people between the ages of 14 and 79 who'd died suddenly, but had previously been healthy.

The only way to answer questions related to the fundamental genetic and neuropathological aspects of autism spectrum disorder is to study brain tissue from individuals with autism spectrum disorder.

Histopathological analysis was performed on the placenta and brain tissue from infants who died.

For the study, Hill compared brain tissue from normal and Parkinson's - like rats using ion mobility — mass spectrometry (IMMS), a process that analyzes both the weight and speed of chemical molecules.

McGehee and his colleague, post-doctoral researcher Huibert Mansvelder, PhD, working with brain tissue from rats, demonstrated how nicotine takes control of the reward pathways.

Mouse brain tissue from three different stages of the mouse brain development; embryonic day 15, postnatal day 2 and postnatal day 21, was studied.

In post-mortem brain tissue from people not diagnosed with Alzheimer's, neither the iron deposits nor the scavenger cells engulfing them were present in that brain region.

Building on this initial finding, the team examined brain tissue from AD patients and normal non-demented humans and found that collagen VI expression was also higher in the Alzheimer's disease patients.

Chen Gu and his team obtained slices of brain tissue from dead mice.

Nakabayashi, Monk, and collaborators studied methylation patterns in adult and umbilical blood and placenta cells from healthy volunteers; brain tissue from a brain bank; and a cultured liver cell line.

This work involves behavior, immunohistochemistry (of brain tissue from mouse models of Alzheimer's), cell culture, and in vitro biochemistry.

The study was conducted by researchers in the UC San Francisco Institute for Neurodegenerative Diseases, using brain tissue from human cases supplied by researchers at the National CJD Survelliance Unit, Western General Hospital, Edinburgh, Scotland.

Past clinical trials of stem cell therapies for chronic stroke patients used cells derived from tumors in humans and brain tissue from fetal pigs.

The findings come from post-mortems of patients who received grafts of brain tissue from aborted fetuses during the 1990s.

Next, Südhof's team examined slices of brain tissue from the mutant mice.

While the team doesn't know the function of those Neandertal gene variants, it began to search for their influence by examining brain tissue from the prefrontal cortex of 14 adults of European, African, and Asian descent, as well as 14 chimpanzees.

Along with the studies in live animals, the research team also studied human brain tissue from Northwestern's Cognitive Neurology and Alzheimer's Disease Center.

The researchers conducted additional studies of the virus using brain tissue from epilepsy patients and showed that the virus does not infect noncancerous brain cells.

In another paper, published yesterday in Morbidity and Mortality Weekly Report, researchers from Brazil and the United States report that Zika virus was present in brain tissue from two newborns in the Brazilian state of Rio Grande do Norte who were born with microcephaly and died a few hours after birth.

A recent generation of studies of postmortem brain tissue from people with schizophrenia, particularly from the laboratory of Professor David Lewis and his colleagues at the University of Pittsburgh, have shed light on schizophrenia - related abnormalities in the interplay of the main excitatory neurons, pyramidal neurons, and a specific class of inhibitory nerve cells, called chandelier cells, in the prefrontal cortex.

Finally, the researchers analyzed samples of human brain tissue from patients with Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis and multiple sclerosis.

«We had brain tissue from autistic individuals as young as 5 and as old as 45 and we found neuroglial inflammation in all of them.

Synthetic, protein - only prions can cause a mad cow — like disease in mice, as can brain tissue from these mice, demonstrating that misfolded proteins are the infectious agents in prion disease.

For the new analysis, his team spent 5 years collecting brain tissue from 59 people who had died or had such tissue removed during surgery for epilepsy at different ages, ranging from before birth to 77 years of age.

New neurons (green) were visible in a newborn's brain (top), but not in brain tissue from a 35 - year - old man (bottom).

When Rupprecht conducts rabies genetic research in China, he finds it is easier to sample brain tissue from deceased humans than from animals.

In an analysis of postmortem human brain tissue from 137 control subjects, they also found an association between the ECR47 risk variant and reduced ADGRL3 expression in the thalamus, a key brain region for coordinating sensory processing in the brain.

When they added these proteins to cultures of brain tissue from aborted human fetuses, the tissue formed folds, as it does in human fetuses at about 20 weeks of gestation.

Three weeks later, they looked at brain tissue from the monkeys and found BrdU to be abundant in the dentate gyrus.

Wondering what was behind those reports, McAninch and colleagues at Rush previously obtained and analyzed brain tissue from the University of Miami Brain Bank from deceased Caucasian male organ donors who at their time of death were young and healthy, without known thyroid problems, to see if they could find any clues.

Again, McAninch and colleagues also continued to collaborate with the University of Miami Brain Bank to obtain and study brain tissue from young, healthy African American brain donors.

Next, the researchers confirmed that brain tissue from donors who had autism indeed contains low amounts of the RORA protein and aromatase.

The researchers found severed axons in regions with inflammation characteristic of the disease — in several cases, more than 10,000 times as many cut axons as in brain tissue from non-MS corpses.

To test their theory, the researchers examined Del - 1 expression in brain tissue from people who had died from MS.. In MS patients with chronic active MS lesions, Del - 1 was reduced compared to both healthy brain tissue and brain tissue from MS patients who were in remission at the time of their death.

Gaining confidence that their compound was appropriately targeting the plaques, the researchers worked with the National Institutes of Health to obtain brain tissue from people who died of Alzheimer's and performed the same type of staining.

This anxious behavior mirrored that of CdLS patients, while autopsied brain tissue from individuals with CdLS showed symptoms of disease that matched those of the experimental mice suggesting that they were a good animal model.

Brain tissue from healthy cows did not contain fibrils.

They also collected brain tissue from the 23 CJD patients and from seven individuals who died of other causes.

The findings tallied with another study which involved screening post-mortem brain tissue from people who had had some form of psychosis.

Right now, treatment for stroke is centered on the first few hours, when rapid intervention with drugs or surgery can prevent brain tissue from dying.

p11 is increased in rodent brains by antidepressants or electroconvulsive therapy, but decreased in an animal model of depression and in brain tissue from depressed patients.

The study found mutations in 607 genes in brain tissue from patients who died from SUDEP that were not seen in the tissue from the living people.

To generate primary NPCs, we minced the brain tissues from neonatal mice carrying the EGFP - transgene and digested them into single cells, which were plated onto low - attachment dishes for neurosphere formation (Figure 1A).

Not exact matches

The imbroglio reached its apex during the second Republican presidential debate, when Carly Fiorina decried the harvesting of a brain from an intact, extracted fetus whose heart had restarted — described on camera by a former tissue procurement technician — as an issue that defines «the character of our nation.»

The building block electronic and protonic actual occasions are, in the case of human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with cells, others which answer to Aristotle's levels of tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.

In the same way, a fetus that has not yet developed a brain is not yet «brain - alive» and has not yet achieved consciousness or thought — and therefore is not morally and qualitatively distinct from other living tissues.

It is our ability to think and reason that makes us human and distinguishes us from all other animals, a piece of tissue, and a baby from an embryo with no measurable brain waves.