The drug caused a 50-fold increase in
brain tumor cell death.
Not exact matches
Glioblastoma is the most lethal form of primary
brain tumor and leads to
death in patients by invading the
brain tissue in a process that allows single
cells to move through normal
brain tissue, which makes complete surgical removal of the
tumor impossible.
The team's experiments in
cell cultures, conducted with funding from an American
Brain Tumor Association Discovery Grant, showed that coibamide A cuts off the cancer
cells» ability to communicate with blood vessels and other
cells, eventually starving the
cell and triggering its
death.
The researchers injected a compound normally used to label
tumor cell division into patients who had agreed to have their
brains examined after
death.
If he can determine how to speed up engulfment of dead
tumor cells from
brain tissue, it is his hope to reduce the harmful inflammation that causes
death of surrounding neurons.
In a laboratory study published in 2012 in Oncology Reports, chokeberries caused the
death of malignant
brain tumor cells.