Sentences with phrase «brain tumor in mice»

The researchers showed that this technique was successful in monitoring gene expression in a brain tumor in mice.

«Altered immune cells clear childhood brain tumor in mice.»

«Lower - carb diet slows growth of aggressive brain tumor in mouse models.»

Engineered human immune cells can vanquish a deadly pediatric brain tumor in a mouse model, a study from the Stanford University School of Medicine has demonstrated.

St. Louis researchers have used a strain of the Zika virus to shrink highly lethal brain tumors in mice.

When administered in restricted amounts, which do not exceed the individual's total energy needs, the KD can also be therapeutic against malignant brain tumors in mice and humans.

But other studies in mice have shown that a ketogenic diet, when implemented in conjunction with radiation therapy for the treatment of brain tumors in mice, resulted in the eradication of these tumors in the majority of the mice.12

Not exact matches

Images show tumor cells in a mouse brain at different days.

In human cells and in mice, the virus infected and killed the stem cells that become a glioblastoma, an aggressive brain tumor, but left healthy brain cells alonIn human cells and in mice, the virus infected and killed the stem cells that become a glioblastoma, an aggressive brain tumor, but left healthy brain cells alonin mice, the virus infected and killed the stem cells that become a glioblastoma, an aggressive brain tumor, but left healthy brain cells alone.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocyteIn the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytein mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

Northwestern Medicine scientists have identified a small RNA molecule called miR - 182 that can suppress cancer - causing genes in mice with glioblastoma mulitforme (GBM), a deadly and incurable type of brain tumor.

The investigators report that trapping virus - loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiforme, the most common brain tumor in human adults and also the most difficult to treat.

Nagoya University - led research team shows in mice the potential of a special immune cell that targets a key protein in tumor growth that helps stop brain cancer.

Several studies have supported a role for cancer stem cells in the aggressive brain tumors called glioblastoma, but those studies involved inducing human tumors to grow in mice, and as such their relevance to cancer in humans has been questioned.

They cross the blood - brain / blood - tumor barrier, and accumulate within brain tumor sites, where they target oncogenes, regulate cell growth and differentiation, reduce tumor burden and prolong survival in our mouse models.»

The researchers took this discovery and, in an animal model, identified a drug that is able to re-activate those immune cells and reduce brain tumor growth, thereby increasing the lifespan of mice two to three times.

To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS) imaging, and demonstrated its use in live cancer cells, tumor xenograft tissues, primary neurons and mouse brain tissues.

This technique is able to distinguish cancer cell lines with differing metabolic activities and reveals heterogeneous uptake patterns in neurons, mouse brain tissues and tumor tissues with clear cell - to - cell variations.

Glioblastomas in lab dishes and mouse brains are fakes, little Potemkin villages that everyone thought were faithful replicas of human glioblastomas but which, lacking tumor stem cells, were nothing of the kind.

Another is that the transplanted bits of tumor act nothing like cancers in actual human brains, Fine and colleagues reported in 2006: Real - life glioblastomas grow and spread and resist treatment because they contain what are called tumor stem cells, but tumor stem cells don't grow well in the lab, so they don't get transplanted into those mouse brains.

Shah next plans to rationally combine the toxin - secreting stem cells with a number of different therapeutic stem cells developed by his team to further enhance their positive results in mouse models of glioblastoma, the most common brain tumor in human adults.

The MRI imaging detected metastatic tumors, including micrometastases, in lung, liver, lymph node, adrenal gland, bone, and brains of the mice.

In the AlphaMed Press journal Stem Cells, Shah's team shows how the toxin - secreting stem cells can be used to eradicate cancer cells remaining in mouse brains after their main tumor has been removeIn the AlphaMed Press journal Stem Cells, Shah's team shows how the toxin - secreting stem cells can be used to eradicate cancer cells remaining in mouse brains after their main tumor has been removein mouse brains after their main tumor has been removed.

To find out whether the virus could help treat cancer in a living animal, the researchers injected either Zika virus or saltwater (a placebo) directly into the brain tumors of 18 and 15 mice, respectively.

A new study shows coibamide A has potent anti-cancer activity in mice and cell cultures that model brain tumors and triple negative breast cancer, two of the most aggressive and difficult - to - treat types of cancer.

Researchers demonstrated that the drugs pemetrexed and gemcitabine killed cells from mouse and human brain tumors, called group 3 medulloblastoma, growing in the laboratory.

The study was carried out in mice to mimic a common brain tumor arising in a genetic condition called neurofibromatosis type 1 (NF1).

«Inhibition of the EZH2 pathway slows growth of tumors in mouse brain derived from glioma stem cells from the enhancing margin of human tumors.

Radiation oncologist Anna Saran at the Italian National Agency for New Technologies, Energy and the Environment in Rome and colleagues studied mice with a mutation in a gene called Patched that makes them susceptible to brain tumors early in life.

«For the first time, we were able to directly monitor oxygen levels in human tumors growing in a mouse brain using EPR oximetry with implantable resonators,» explained Khan.

CSCs were prepared from 231BrM and CN34BrM cells that were infected with lentivirus carrying with or without miR -7-2, and they were transplanted into nude mice through intracardiac injection followed by monitoring metastatic tumor growth in the brain.

After 5 weeks, metastatic tumor growth in the brain was prominent in all mice that received CSCs carrying vector only.

In their search for novel, tumor - specific therapies that could target multiple brain metastases without damaging adjacent tissues, the research team first developed a mouse model that more closely mimics what is seen in patientIn their search for novel, tumor - specific therapies that could target multiple brain metastases without damaging adjacent tissues, the research team first developed a mouse model that more closely mimics what is seen in patientin patients.

After first verifying that stem cells injected to the brain would travel to multiple metastatic sites and not to tumor - free areas in their model, the team injected stem cells loaded with oHSV into the carotid artery of metastasis - bearing mice..

In a new paper in Science Translational Medicine, the U-M team describes how they developed a novel brain tumor model in micIn a new paper in Science Translational Medicine, the U-M team describes how they developed a novel brain tumor model in micin Science Translational Medicine, the U-M team describes how they developed a novel brain tumor model in micin mice.

If further research in the mice bears out, they could soon be tested in children whose brain tumors also show a decrease in ATRX production.

They also found that drugs that target this newly identified cancer pathway can prevent tumor growth, both in human cancer cells and mice with a form of brain cancer.

In addition to developing the new genetically engineered mouse model for the form of cancer called glioblastoma multiforme, the researchers made a key discovery about brain tumor biology via the mice.

«We wanted to see whether these newly generated neurons could result in tumor growth after transplanting them into mouse brains,» said Karen Ring, UCSF Biomedical Sciences graduate student and the paper's lead author.

The team further demonstrated that, in mice that had DIPG tumors implanted in their brain stems, infusing panobinostat directly into the brain stem slowed tumor growth.

The drug restricted the tumor's growth in a lab dish and improved the survival time of mice that had the tumor implanted into their brains, according to researchers at the Stanford University School of Medicine, in collaboration with colleagues at other institutions.

Although vaccination induces an inflammatory response during pregnancy, the magnitude and the duration of response is much lower and shorter, respectively, for influenza vaccination than viral infection.27 Like infection, influenza vaccination during pregnancy has been reported to induce a transient increase in the levels of a number of proinflammatory cytokines, including interleukin 6, tumor necrosis factor α, and C - reactive protein.27 - 30 Studies on mice found an association between high interleukin - 6 levels during pregnancy and abnormal behavior and brain structure.19 However, in epidemiological studies, associations between maternal cytokine levels and ASD have been mixed.

This evolutionary and metabolic approach to brain cancer management is supported from studies in orthotopic mouse brain tumor models and from case studies in patients.

Adrienne Scheck has shown that when applied with curative doses of radiation therapy, the ketogenic diet can make brain tumors vanish in mice.2 However, many dietary changes appear to blunt cancer growth in mice, 3 and the effects in humans are less clear.

Some studies on mice resulted in brain tumors.

Administers veterinary staff approved supportive care such as dietary additives, supplemental environmental enrichment for hiding and chewing, heating pads, and subcutaneous fluids to distressed mice and rats in studies perusing new treatments for brain tumors, Parkinson's disease, heart disease, and emphysema and genetic studies charting the development of lung cancer and diabetes.