Sentences with phrase «brain tumor tissue»

Philadelphia, PA About Blog The Children's Brain Tumor Tissue Consortium is committed to discovering new cures and better therapies for children with pediatric brain tumors.

Furthermore, there was no discernable brain tumor tissue detected using magnetic resonance (MRI) or fluorodeoxyglucose - positron emission tomography (FDG - PET) imaging scans.14

One of the most difficult things for a brain surgeon is figuring out exactly where a brain tumor starts and stops because brain tumor tissue can be hard to distinguish from the rest of the brain.

Not exact matches

Although there have been great advances made in the treatment of leukemias and other cancers, little is known about how Glioblastomas are formed and how these tumors infiltrate the brain tissue.

In 2002 scientists showed that cytomegalovirus, or CMV, was active in the brain tumors but not the surrounding healthy tissue of all 27 patients they tested who had glioblastoma multiforme.

To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS) imaging, and demonstrated its use in live cancer cells, tumor xenograft tissues, primary neurons and mouse brain tissues.

This technique is able to distinguish cancer cell lines with differing metabolic activities and reveals heterogeneous uptake patterns in neurons, mouse brain tissues and tumor tissues with clear cell - to - cell variations.

However, because of the aggressive way glioblastomas invade surrounding brain tissue, it is impossible to remove all parts of the tumors, and the cancer eventually returns and spreads.

Glioblastoma is the most lethal form of primary brain tumor and leads to death in patients by invading the brain tissue in a process that allows single cells to move through normal brain tissue, which makes complete surgical removal of the tumor impossible.

For the study, researchers investigated tissue samples from 297 people with brain tumors.

To test this idea, the researchers utilized two mouse models of human breast cancer metastasis and found dormant disseminated tumor cells residing upon the membrane microvasculature of lung, bone marrow and brain tissue.

However, the proclivity of glioblastoma to invade adjacent brain tissue prevents the surgical removal of all tumor cells.

They showed that the iKnife could distinguish normal and tumor tissues from different organs, such as breast, liver, and brain, and could even identify the origin of a tumor that was a metastasis, a secondary growth seeded by a primary tumor elsewhere in the body.

«We are talking about fast - growing tumors that invade normal brain tissue and are very difficult to treat,» said Orin Bloch, MD, a neurosurgeon at Northwestern Memorial Hospital and lead author of the study.

Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.

Past clinical trials of stem cell therapies for chronic stroke patients used cells derived from tumors in humans and brain tissue from fetal pigs.

I am particularly interested in the neuronal tissue and the analysis of gene regulators implicated in both differentiation and brain tumor development.

In their search for novel, tumor - specific therapies that could target multiple brain metastases without damaging adjacent tissues, the research team first developed a mouse model that more closely mimics what is seen in patients.

Furthermore, we examined the expression of KLF4 in brain metastatic tissues by immunohistochemistry and found that KLF4 was expressed more in the nucleus and significantly less in cytosol in brain metastatic tissues compared with primary tumors (Fig. 6C and D).

The safe use of a stem - cell - based therapy against brain metastasis would require preventing the engineered cells from persisting within the brain, where they could affect normal tissue and possibly give rise to new tumors.

To further validate the clinical significance of miR - 7 and KLF4 in brain metastasis of breast cancer, we microdissected tumor tissues from both primary and brain metastatic lesions followed by conducting TaqMan qRT - PCR.

We found that the expression of miR - 7 was significantly lower in brain metastatic tumors than that in primary tumor tissues (Fig. 6A, left), whereas the expression of KLF4 was significantly higher in brain metastatic tissue compared with primary tumors (Fig. 6A, right).

Proton therapy delivers high radiation doses directly to the brain tumor site, with no damage to nearby healthy tissue.

Sophisticated radiation therapy technologies for treating brain and spinal tumors, aneurysms, and blood vessel abnormalities while causing minimal damage to healthy tissues.

A three - minute film about a tiny molecule that lights up brain tumors so neurosurgeons can better distinguish cancer from normal tissue has a chance for its own moment in the spotlight in the Sundance Film Festival in January.

Li - Fraumeni syndrome (LFS) is a genetic disorder associated with an increased risk of developing several forms of cancer, including soft tissue sarcoma, breast cancer, leukemia, lung cancer, brain tumors and adrenal gland tumors.

3/24/2008 Non-Invasive Imaging Provides Window Into Genetic Properties of Brain Tumors Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surBrain Tumors Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or suTumors Doctors diagnose and prescribe treatment for brain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surbrain tumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or sutumors by studying, under a microscope, tumor tissue and cell samples obtained through invasive biopsy or surgery.

LA JOLLA, CA — Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain...

If he can determine how to speed up engulfment of dead tumor cells from brain tissue, it is his hope to reduce the harmful inflammation that causes death of surrounding neurons.

Treatment of malignant glioma using gene transfer modalities typically consists of surgical debulking of the tumor mass followed by the administration of the viral vectors into the brain tissue surrounding the tumor cavity.

At McCain's request, the Mayo Clinic, which is treating him, released a statement explaining that «tissue pathology revealed that a primary brain tumor known as a glioblastoma was associated with the blood clot» that was removed.

Expertise: Interactions of Ionizing and Non-ionizing Radiation with Biological Tissues, Novel Laser - Based Therapeutics for Brain Tumors, Nanoparticle - Based Photothermal Therapy

Sometimes, after examining tumor tissue, the tumor is diagnosed as a metastatic brain tumor but the patient has no history of cancer.

When a tumor develops in the brain, spinal tissue, or affecting the nervous system, tumor growth is a significant concern due to the location around delicate tissue and structures.

The linear accelerator (LINAC) uses high energy targeted x-ray beams to treat many types of cancer, including nasal tumors, oral tumors, soft tissue sarcomas, and brain tumors.

Tumor types that may respond well to radiotherapy, or where radiotherapy can improve quality of remaining life by reducing pain, include mast cell tumors, sarcomas (cancer of bone, muscle or various connective tissue), lymphosarcoma, and tumors of the mouth, nose, brain and thyroid.

Early - delayed side effects: up to 40 % of pets can have worsening of their original symptoms in the first 1 - 5 months after RT (due to irritation of the normal brain tissue surrounding the dying tumor).

Perhaps the most frequently diagnosed of these is a neoplastic disease called meningioma, which is a type of tumor that develops in the thin protective tissue — the meninges — that covers a cat's brain.

Secondly, brain tissue can not regenerate, and therefore removal of normal brain tissue surrounding a tumor can have unacceptable repercussions for the patient.

The brain and its bath of cerebrospinal fluid takes up almost all the room and when a tumor begins to grow, the brain tissue is compressed.

If the tumor is large, local effects of the tumor invading surrounding tissues in the brain can be the limiting factor in survival.

There are a variety of types of brain tumors that can occur in the brain tissue, and they may be classified as benign (noncancerous) or malignant (cancerous).