The phrase
"brain ventricles" refers to cavities or hollow spaces found inside the brain. These ventricles are filled with a fluid called cerebrospinal fluid, which helps protect and nourish the brain.
Full definition
When the one of these lincRNA, called megamind, is reduced in zebrafish, the embryos have abnormally shaped heads and
enlarged brain ventricles, as indicated by the arrow.
Though
faster brain ventricle enlargement is a marker for cognitive decline and the development of neurodegenerative diseases such as Alzheimer's, the effects of sleep on this marker have never been measured.
Reduction of one of the lincRNAs, which they called cyrano, caused the zebrafish to have enlarged snouts, small heads and eyes, and short, curly tails, while the zebrafish lacking the lincRNA they called megamind had abnormally shaped heads and
enlarged brain ventricles.
However, there was a big bump along the road to the current trial, when the NCATS - convened team, in a first attempt, injected the drug directly into
the brain ventricles — the cisterns that hold cerebrospinal fluid — using an implanted reservoir normally deployed to inject brain cancer chemotherapy.
Located in the walls of
the brain ventricles, the choroid plexus is best known for producing cerebrospinal fluid, which forms a protective mechanical cushion and immunological buffer for the brain.
The choroid plexus located in
the brain ventricle is marked with red in the brain image.
«Cilia are found throughout the body, so defects in cilia formation affect cells that line airways,
brain ventricles or the reproductive track,» said the study's lead author Julie Craft, a sixth - year doctoral student at UGA.
If owners want a more positive diagnosis, the sizes of
the brain ventricles in relation to their brain size need to be measured.
Ultrasound evaluations through the fontanel can reveal dilated or enlarged
brain ventricles (open areas in each half of the brain).