Sentences with phrase «brains and spinal cords by»

The Dodt and Frank Bradke laboratories later developed the 3DISCO (3 - dimensional imaging of solvent cleared organs) method of imaging rodent brains and spinal cords by combining Ultramicroscopy with tetrahydrofuran - based tissue clearing (13,14).

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Some of the original songs Williams wrote for the band were inspired by journal entries he'd written in the Shepherd Center, a spinal cord and brain injury rehabilitation facility.
The device, developed by composer and computer - music specialist Eduardo Miranda of the University of Plymouth, UK, working with computer scientists at the University of Essex, should eventually help people with severe physical disabilities, caused by brain or spinal - cord injuries, for example, to make music for recreational or therapeutic purposes.
Although the find was remarkable, it wasn't until this year that a team led by French paleoanthropologist Michel Brunet used CT scans to create a virtual model of the skull, revealing precise measurements of the size of the brain cavity and information about the angle at which the spinal cord exits the brain.
The study conducted by an interdisciplinary team headed by Professor Martin Schwab from the Brain Research Institute at the University of Zurich and ETH Zurich's Neuroscience Center is another milestone in research on the repair of brain and spinal cord injuBrain Research Institute at the University of Zurich and ETH Zurich's Neuroscience Center is another milestone in research on the repair of brain and spinal cord injubrain and spinal cord injuries.
However, peripheral nerves — nerves outside of the brain and spinal cord — are able to regenerate by releasing a variety of neurotrophic factors, which are protein - like molecules that support growth and maintenance of neurons.
«Someday AAV9 may help us treat spinal cord injury as well as diseases of the spinal cord and brain by carting genes right to the place they're needed,» Kaspar says.
Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is marked by a cascade of cellular and inflammatory events that weakens and kills vital motor neurons in the brain and spinal cord.
Functional loss of limb control in individuals with spinal cord injury or stroke can be caused by interruption of the neural pathways between brain and spinal cord, although the neural circuits located above and below the lesion remain functional.
Morphine and its derivatives seem to exert their effects by binding to specific receptor sites on cells in the brain and the spinal cord.
It is produced by the brain and spinal cord into early adulthood as it is needed for many developmental processes, and although earlier studies of human white matter hinted at its involvement in skill learning, this is the first time it has been confirmed experimentally.
The most infectious organs — where BSE prions cluster — are the brain and spinal cord, followed, on a less infectious level, by the pineal, pituitary, and adrenal glands, spleen, tonsils, placenta, lymph nodes, ileum, part of the colon, dura mater, and cerebrospinal fluid.
In a major breakthrough, a team led by researchers at the Salk Institute and Harvard Medical School have identified an important neural mechanism in the spinal cord that appears to be capable of sending erroneous pain signals to the brain.
Now, to enable widespread gene delivery throughout the central and peripheral nervous systems, Caltech researchers have developed two new variants of a vector based on an adeno - associated virus (AAV): one that can efficiently ferry genetic cargo past the blood - brain barrier; and another that is efficiently picked up by peripheral neurons residing outside the brain and spinal cord, such as those that sense pain and regulate heart rate, respiration, and digestion.
SMA is caused by a mutation in a gene that is vital for the survival of nerve cells that connect the brain and spinal cord to the muscles, known as motor neurons.
Neurocutaneous disorders are caused by abnormal development of cells in the embryonic stage, leading to tumors in various parts of the body, including the skin, organs, bones, brain and spinal cord.
In a new study published in the Journal of Neuroimmune Pharmacology, Drs. Ewa Kozela, Ana Juknat, Neta Rimmerman and Zvi Vogel of Tel Aviv University's Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases and Sackler Faculty of Medicine demonstrate that some chemical compounds found in marijuana can help treat MS - like diseases in mice by preventing inflammation in the brain and spinal cord.
BREATHLESS Nerve endings in the lungs send signals — triggered by force - detecting proteins — to the brain and spinal cord that help regulate breathing.
This promises to make proton therapy an option for thousands more cancer patients by reducing the risks of healthy tissue being damaged during treatment, particularly in vulnerable parts of the body such as the brain, eye and spinal cord.
For example, it could be used to image neurons in living mice by combining the Raman scattering technique with existing methods in which tiny windows are implanted in the brains and spinal cords of laboratory animals.
Shenoy's lab pioneered the algorithms used to decode the complex volleys of electrical signals fired by nerve cells in the motor cortex, the brain's command center for movement, and convert them in real time into actions ordinarily executed by spinal cord and muscles.
Even after control by the brain has been lost, the spinal cord continues to send out motor signals, which are translated into movements of the legs and / or wings.
Here, the research team led by Associate Professor Yukio Nishimura, National Institute for Physiological Sciences (NIPS), Natural Institutes of Natural Sciences (NINS), and Masahiro Sawada, a former graduate student of Kyoto University, and Dr. Hirotaka Onoe, a team leader at RIKEN Center for Life Science Technologies found that the nucleus accumbens, that control motivation in the brain, activates the activity of the motor cortex of the brain, and then promotes recovery of motor function during the early stage of recovery after spinal cord injury.
A further 228 cases of CJD were caused by transplantation of prion - contaminated dura mater — the membrane surrounding the brain and spinal cord — prepared from cadavers around the world.
To prevent collateral damage to precious nerve cells during immune skirmishes, the brain and spinal cord are tightly sealed off from the rest of the body by the blood - brain barrier.
By contrast, drugs targeting delta opioid receptors in the peripheral nervous system rather than the brain and spinal cord produce fewer side effects in animals and have a much lower abuse potential.
These problems are caused by a type of white blood cells called T cells that, after becoming activated, find their way into the brain and attack the protective covering — myelin — of neurons in the brain and spinal cord, causing inflammation and damage to the central nervous system.
Earlier this year, another team reported using a brain machine interface to allow a quadriplegic to move his finger and arms, but that system directly activated arm muscles with brain signals detected by implanted electrodes, bypassing the damaged spinal cord.
He and colleagues reveal that eight Brazilians paralyzed because of spinal cord injuries regained some small but significant sensation and muscle control in their lower limbs after many months of training with the robotic exoskeleton, and by a virtual reality avatar also controlled by brain signals.
He said this technology may one day help patients affected by various brain and spinal cord injuries such as strokes and traumatic brain injury.
The condition is caused by the immune system malfunctioning and mistakenly attacking nerves in the brain and spinal cord.
Many cases of ALS are sparked by a toxic build - up of certain proteins, which cause neurons in the brain and spinal cord to die.
«This means Ind - Cl works in two ways: through the immune system in terms of reducing brain and spinal cord inflammation, and directly by remyelinating the axons.
The face is cut and bruised by direct impacts, but damage to the brain is caused largely by rotational acceleration of the cerebral cortex around the much smaller midbrain and spinal cord.
Now, by studying the lamprey, Caltech researchers have discovered an unexpected mechanism for the evolution of the neurons of the peripheral nervous system — nerves outside of the brain and spinal cord.
«This affiliation will enable us to make Kessler Foundation's scientific advances more widely available to people with physical and cognitive disabilities caused by brain injury, cancer, multiple sclerosis, spinal cord injury and stroke.»
Those naturally produced opioids, and the opioid drugs that imitate them, inhibit pain by acting on three kinds of opioid receptors — mu, kappa and delta — that are found on the outside of nerve cells in the brain, spinal cord, digestive tract and elsewhere.
This damages nerve cells by blocking their ability to make the proteins needed for synaptic function and leads to the death of neurons in the brain and spinal cord.
This disorder is marked by the loss of motor neurons in the brain and spinal cord, and atrophy of the frontal and temporal lobes.
About Kessler Foundation: Kessler Foundation, a major nonprofit organization in the field of disability, is a global leader in rehabilitation research that seeks to improve cognition, mobility, and long - term outcomes - including employment - for people with neurological disabilities caused by diseases and injuries of the brain and spinal cord.
Kessler Foundation, a major nonprofit organization in the field of disability, is a global leader in rehabilitation research to improve cognition, mobility, and long - term outcomes - including employment - for people with neurological disabilities caused by diseases and injuries of the brain and spinal cord.
Scientists at Prothena had confirmed that several of their candidate antibodies were able to clear AS pathology out of the brains and spinal cords of mouse models of PD and related disorders, substantially shielding them against the PD - like motor and cognitive impairments suffered by their untreated cousins.
Last year, the run / walk raised enough funds to provide a grant to the Pediatric Brain and Spinal Cord Tumor Research Initiative, headed by Dr. Charles Rubin, a pediatric oncologist at Comer Children's Hospital.
«Our implantable devices aim to bridge such lost connections by decoding brain signals and stimulating the appropriate part of the spinal cord to enable the person to move again.»
The cause of her readmission into hospital was meningitis — infection of her nervous system, brain and spinal cord, by Ebola virus that remained from her initial infection.
Furthermore, the success of this project can lead to the development of novel axon - regenerating therapeutics that could transform the clinical treatment of angle - closure glaucoma and other types of optic neuropathies, as well as have the potential to be adapted to regenerating the long - distance axonal projections damaged by spinal cord injury, brain trauma, and white matter stroke.
Kessler Foundation conducts research in people with cognitive and mobility deficits caused by multiple sclerosis, spinal cord injury, stroke, traumatic brain injury and other neurological disorders.
We've been able to get around this by injecting them directly into the cerebrospinal fluid (CSF), the fluid surrounding and cushioning the brain and spinal cord.
About Kessler Foundation Kessler Foundation, a major nonprofit organization in the field of disability, is a global leader in rehabilitation research that seeks to improve cognition, mobility and long - term outcomes, including employment, for people with neurological disabilities caused by diseases and injuries of the brain, spinal cord and muscles.
GM1 is an extremely severe, autosomal recessive disease caused by a mutation in the GLB1 gene and resulting in the progressive destruction of neural cells in the brain and spinal cord.
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