Sentences with phrase «brains of their human patients»

In the brain, his FFI mice develop neuronal loss in the thalamus and his CJD mice experience spongiosis in the hippocampus and the cerebellum, reflecting the damage seen in the brains of human patients.

Both Drosophila and mouse models with centrosome dysfunction showed abnormalities in the neuroepithelium reminiscent of the ones described in brains of human patients.

Not exact matches

Otherwise, the patient may suffer the loss of human intellect due to a tremendous decrease of brain.

In order to protect infant safety and ensure the patient and human rights of mothers and babies, we have built a non-profit organization committed to: (1) the study of exclusive breastfeeding complications that can result in brain injury and, in the most severe instances, death; and (2) raising public awareness to signs of infant hunger and the consequences that can result based on peer - reviewed research.

However, abstinent patients report cravings when given reminders of their drug - associated environment or cues, and animals and humans share similar enzyme pathways and brain structures.

A recent study published in Annals of Neurology reports that healthy human tissue grafted to the brains of patients with Huntington's disease in the hopes of treating the neurological disorder also developed signs of the illness, several years after the graft.

HBI member V. Wee Yong, PhD and research associate Susobhan Sarkar, PhD, and their team including researchers from the Department of Clinical Neurosciences and the university's Southern Alberta Cancer Research Institute, looked at human brain tumor samples and discovered that specialized immune cells in brain tumor patients are compromised.

Specifically, rodents genetically modified to express human amyloid precursor protein (hAPP), which can lead to the debilitating plaques that form in the brains of Alzheimer's patients, seem to struggle to find the hidden platform relative to their healthy peers.

A University of Illinois at Chicago researcher will test whether brain stimulation combined with gait training can improve patients» ability to walk after a stroke, under a $ 1.5 million grant from the National Institute of Child Health and Human Development.

By assessing the survival of the cells that engulf the particles and measuring the levels of red or green light that they emitted, the researchers determined which formulation of particles performed best, then tested that formulation in mice with human brain cancer derived from their patients.

Delgado implanted similar electrode arrays, or «stimoceivers,» in the brains of cats, monkeys, chimpanzees, and even human psychiatric patients.

Using a technique called nuclear magnetic resonance spectroscopy, the researchers measured the concentrations of 21 metabolites key to nerve function in the brains of 10 deceased schizophrenia patients and 12 normal human controls.

Then a frustrated group of epilepsy physicians invited computer nerds around the world to take a shot instead, providing data sets recorded from the brains of human epilepsy patients and epileptic dogs.

In humans, this region could be a target for bringing some brain injury patients out of a comatose state via electrical stimulation, says lead author Nigel Pedersen, MD, assistant professor of neurology at Emory University School of Medicine and an epilepsy specialist at Emory Brain Health Cebrain injury patients out of a comatose state via electrical stimulation, says lead author Nigel Pedersen, MD, assistant professor of neurology at Emory University School of Medicine and an epilepsy specialist at Emory Brain Health CeBrain Health Center.

Now he and his team are putting cells from human brain tumors into the organoids, which have reached the level of development and complexity of a 20 - week - old human fetus's, to see whether they reprise what happens in patients.

2015 will see the start of the first human clinical trial of a gene silencing or huntingtin - lowering drug, which specifically aims to reduce production of mutant huntingtin in the brains of HD patients.

Fried realized that medical procedures like this one presented a rare scientific opportunity: Patients being examined for neurosurgery allow researchers to investigate the human brain in action, exploring the functions of different regions in precise detail and in real time.

The goal of the study was to explore whether fecal microbiota from human IBS patients with diarrhea has the ability to influence gut and brain function in recipient mice.

The new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000 human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk factor for psychiatric disease by interfering with the way the brain regulates connections between neurons.

University of Alabama at Birmingham researchers have found that amounts of this microRNA are significantly elevated in the brains of experimental rats with induced depression from corticosterone treatment, in the post-death brains of humans diagnosed with MDD and in peripheral blood serum from living patients with MDD, according to a study by led by Yogesh Dwivedi, Ph.D., the Elesabeth Ridgely Shook Endowed Professor and director of Translational Research, UAB Mood Disorders Program, Department of Psychiatry.

Some scientists aren't persuaded that the chimp brains really do match those of human Alzheimer's patients.

Extracts from the brains of FFI patients transmitted disease to transgenic mice expressing a chimeric human - mouse PrP gene about 200 days after inoculation and induced formation of the 19 - kilodalton PrPSc fragment, whereas extracts from the brains of familial and sporadic Creutzfeldt - Jakob disease patients produced the 21 - kilodalton PrPSc fragment in these mice.

The potential prospects include superintelligent machines, nonaging bodies, direct connections between human brains or between brain and computer, fully realistic virtual reality, and the reanimation of patients in cryonic suspension.

If the new mechanism also operates in the human brain and can be potentiated, this could become of clinical importance not only for stroke patients, but also for replacing neurons which have died, thus restoring function in patients with other disorders such as Parkinson's disease and Huntington's disease,» says Olle Lindvall, Senior Professor of Neurology.

Finally, the researchers analyzed samples of human brain tissue from patients with Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis and multiple sclerosis.

Researchers have long known that in patients with Alzheimer's, the areas of the human brain clogged with senility - associated plaques also bristle with inflammatory cells and cytokines.

But it wasn't until May this year that researchers measured the firing of mirror neurons in humans directly, using electrodes implanted in the brains of epileptic patients awaiting surgery (Current Biology, vol 20, p 750).

If it works in humans, the technique could prolong the lives of some brain cancer patients, and it might be applicable to other types of cancer as well.

To uncover the identities and roles of these channels in humans, Donald Welsh and colleagues from the University of Calgary investigated smooth muscle cells from cerebral arteries harvested from patients undergoing brain surgery.

While the animals» brains experience dramatically reduced blood flow during hibernation, just like human patients after a certain type of stroke, the squirrels emerge from their extended naps suffering no ill effects.

After confirming in mouse models that cells from HER2 - positive breast cancers became resistant to anti-HER2 treatment when implanted into the brain but not into other tissues, the investigators found that HER3 is overexpressed in brain metastases of HER2 - positive breast cancers from both mice and human patients.

Past clinical trials of stem cell therapies for chronic stroke patients used cells derived from tumors in humans and brain tissue from fetal pigs.

A recent human study also indicated a genetic association of the αCaMKII gene with bipolar disorder, and decreased expression of αCaMKII has been observed in postmortem brains of patients with bipolar disorder.

«The group had the data in human stem cells and a fly model, but we really wanted to know whether we could see this in the brains of patients,» says Rothstein.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

Klann says some of the proteins they found «were also reported as being altered in the brains of both (autopsied) rodents and human patients treated chronically with antipsychotics.»

«The behaviors displayed by IED patients represent the expected consequence of altered brain structure and function underlying impulsive aggression in humans.»

Penfield stimulated the brain with electricity in patients undergoing epilepsy surgery, and used the results to draw a â $ œmotor homunculusâ $: a distorted representation of the human body within the brain.

October 13, 2016 Researchers help paralyzed man regain sense of touch through a robotic arm For the first time ever, a human patient is able to experience the sense of touch through a robotic arm that he controls with his brain, with the help of technology created by researchers from Pitt and UChicago's Sliman Bensmaia.

«Our approach allowed us to grow human neurons in a dish that contained the exact same mutation as the neurons in the brain of the patient,» explained first author Helen Fong, PhD, who is also a California Institute for Regenerative Medicine postdoctoral scholar.

Together, they found that the human gene PTCHD1, which is missing in around 1 % of patients with autism, plays a crucial role in suppressing noise and allowing the brain to perceive signals unimpeded.

This project provides the opportunity to record intracranial LFP signals from the olfactory as well as the limbic regions of the human brain while patients participate in various olfaction - based behavioral paradigms.

Since the discovery (in a human patient named H.M.) that hippocampal removal can lead to the inability to form new memories, the hippocampus has been studied as one of the primary sites of memory formation in the brain.12 While it has also been known since O'Keefe and Dostrovsky's initial experiments that the hippocampus plays a basic role in spatial navigation, how and why this tiny portion of the brain can host both spatial maps and complex memories has remained poorly understood.

Scientists at Wake Forest Baptist Medical Center and the University of Southern California (USC) Viterbi School of Engineering have demonstrated a neural prosthetic system that can improve a memory by «writing» information «codes» (based on a patient's specific memory patterns) into the hippocampus of human subjects via an electrode implanted in the hippocampus (a part of the brain involved in making new memories).

This has been proven in human cells in vitro — Aβ reduces the binding of insulin to its receptor in a dose - dependent manner.28 Insulin levels are already reduced in the brain of AD patients, and now there is something interfering with the proper binding of what little insulin is present.

(Chlorella, January 19th, 2012) Because it is believed that a powerful phytochemical found in chlorella can even rebuild nerve damage in human brain and nervous system chlorella is being often used in the recovery of patients with Parkinson's and Alzheimer's disease.

When Breath Becomes Air chronicles Kalanithi's transformation from a naïve medical student «possessed,» as he wrote, «by the question of what, given that all organisms die, makes a virtuous and meaningful life» into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality.

Other studies have shown that dogs affected by this syndrome show deposition of amyloid (a protein) in their brains in patterns very similar to the amyloid plaques found in the brains of human Alzheimer's patients.

Terry Regan (who attracts praise for his «sympathetic and patient handling of cases») heads the practice, which includes John Vallance; collectively they bring more than 50 years of experience handling clinical negligence claims involving brain injury, cancer, product liability, cosmetic surgery and the Human Rights Act.