Sentences with phrase «brains using novel»

Not exact matches

The researchers are planning to use the novel mouse model to study how ErbB4 may coordinate brain activities, in an effort to learn more about mechanisms behind attention deficit disorders.
The study used a novel mouse model to study brain functions.
In the future, studies are aimed at using novel molecular approaches to selectively delete AMPK in specific brain regions associated with nicotine dependence to better understand the functional role of this protein in addiction.
«This approach, where we use brain imaging to dissect the specific neural pathways of complex syndromes, is very novel and important.
This new study of non-military, civilian trauma patients visiting the emergency department builds on recent research conducted by Dr. Samadani, supported through the Cohen Veterans Center, which found that the use of this novel eye - tracking technology could reveal edema, or swelling, in the brain as a potential biomarker for assessing brain function and monitoring recovery in people with head injuries.
By using a combination of advanced genetics, molecular approaches, and microscopy techniques, they found that this signaling pathway is used in the adult brain in a completely novel way.
Mammalian brain growth is studied in this paper which shows that a widely accepted hypothesis of how the mammalian brain proportions grow and evolve does not work, using a novel method of micro-CT scan that allows the first fast data acquisition of soft tissue growth in tiny mammals.
Children with tuberculosis meningitis — a brain and spinal cord infection that leads to disability and death — have a biological fingerprint that can be used to assess the severity of the condition, help decide the best course of treatment, and provide clues for novel treatments, scientists at the Francis Crick Institute, Imperial College London and the University of Cape Town reveal.
Thamara Perera, FRCS, of Queen Elizabeth Hospital Birmingham, in the UK, and his colleagues used microdialysis, a novel technique to study the differences in basic energy metabolism between organs from DCD and brain death donors.
This approach has been used in other brain disorders, such as schizophrenia, which has already led to novel insights and alternative treatment approaches in that disorder.
In a novel animal study design that mimicked human clinical trials, researchers at University of California, San Diego School of Medicine report that long - term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.
«Novel viral vectors deliver useful cargo to neurons throughout the brain and body: The viruses reach their targets via the bloodstream and could be used to treat neural disorders.»
«Using novel computational methods, we have pointed to new biological pathways that act in the brain to regulate overall obesity, and also to a different set of pathways related to fat distribution that regulate key metabolic processes,» says senior author Joel Hirschhorn, M.D., Ph.D., Concordia professor of pediatrics and professor of genetics at Boston Children's Hospital and Harvard Medical School, and co-director of the Broad Institute Metabolism Program.
Muotri noted that the research represents one of the first efforts to use iPSCs and brain in - a-dish technology to generate novel insights about a disease process and not simply replicate data from other models.
Levitin then teamed up with Scott Grafton, a leading brain - scan expert at the University of California at Santa Barbara, to use two novel techniques to analyze the scans.
Using novel technologies developed at HMS, the team looked at how a single sensory experience affects gene expression in the brain by analyzing more than 114,000 individual cells in the mouse visual cortex before and after exposure to light.
A novel twist on the young field of optogenetics may provide a new way to study living human brains as well as offering innovative therapeutic uses.
Using a two - ply of flexible, thin plastic, scientists have created novel electronic sensors that send signals to the brain tissue of mice that closely mimic the nerve messages of touch sensors in human skin.
«We were able to develop this very novel method to go to a single neuron and manipulate how it computes» by using drugs to block neurotransmitters at the level of a single nerve cell in a frog brain, and then measuring what happens to that neuron in response to frog calls, Alluri says.
The study, published in the journal Brain, used a novel brain imaging method to identify altered brain connections in people withBrain, used a novel brain imaging method to identify altered brain connections in people withbrain imaging method to identify altered brain connections in people withbrain connections in people with ASD.
Rose and neuroscience doctoral student Rishi Alluri used a novel combination of recording electrical activity of single brain cells and blocking neurotransmitter chemicals that carry nerve signals from one nerve cell or neuron to the next.
Researchers from King's College London have for the first time used a novel form of MRI to identify crucial developmental processes in the brain that are vulnerable to the effects of premature birth.
In several steps using a new strategy and a novel drug, Burkhard Becher's team from the Institute of Experimental Immunology at the University of Zurich has now succeeded in doing exactly this in the case of glioblastoma, one of the most dangerous brain tumors.
«Grape - derived compounds may promote resilience against depression, researchers find: New study used DNA epigenetic mapping to analyze novel inflammatory mechanisms influencing brain circuitry associated with depression.»
Aurélie Pala and Carl Petersen at EPFL's Brain Mind Institute used a novel technique, «optogenetics,» that has been making significant inroads in the field of neuroscience in the past ten years.
Lead author Dr Shelby Putt, from the Stone Age Institute, said: «This work offers novel insights into prehistoric cognition using a cutting - edge neuroimaging technique that allows people to engage in complex actions while we are measuring localized brain activity.
Stimulation using microwires presents a novel opportunity to improve selective and natural activation of neuronal circuits in the human brain.
«This study, done using a mouse model, expands our understanding of how associative fear memory for a relevant context is encoded in the brain,» said Cho, the lead author of the study and a member of the UCR School of Medicine's Center for Glial - Neuronal Interactions, «and could inform the development of novel therapeutics to reduce pathological fear in PTSD.»
The George lab has made seminal contributions to the field including: discovering a novel population of neurons in the brain of humans, rats and mice that are involved in nicotine dependence, identifying neuronal ensembles responsible for nicotine and alcohol addiction, and unveiled the cellular and molecular changes associates with long term use of nicotine, cocaine, methamphetamine and alcohol use on the brain.
The BrainGate research was praised for «enabling a new understanding of human brain function and the development of a novel, fully - implanted platform neurotechnology capable of wirelessly transmitting large numbers of neural signals from multiple types of sensors for use in Brain Computer Interface, epilepsy monitoring, and neuromodulation applications.&rbrain function and the development of a novel, fully - implanted platform neurotechnology capable of wirelessly transmitting large numbers of neural signals from multiple types of sensors for use in Brain Computer Interface, epilepsy monitoring, and neuromodulation applications.&rBrain Computer Interface, epilepsy monitoring, and neuromodulation applications.»
The goal is to use this new understanding of the brain to develop novel and effective treatments for schizophrenia and other disorders of compromised glutamatergic signaling.
Scientists from Kessler Foundation and Rutgers University compared information flow in the brain in individuals with traumatic brain injury and healthy controls, using neuroimaging and a novel working memory task, CapMan, which measures both working memory capacity and the mental manipulation of information in working memory.
«Nose to Brain Delivery of BIIB033 via the Olfactory Region for the Regenerative treatment of Multiple Sclerosis Using Novel Multi-functional Biomaterials Combined with a Medical Device»
Then they used their novel selection process to determine which variants most effectively delivered genes to astrocytes in the brain.
Our research lab uses neuroimaging to better understand brain - to - muscle / motor deficit and impairment as well as recovery following novel rehabilitation interventions.
Both are addressed by recent developments that include: 1) a novel hyperscanning technology (functional near - infrared spectroscopy, fNIRS) that acquires hemodynamic signals simultaneously between two naturally interacting partners using a spectral absorbance technique that detects changes in hemodynamic signals acquired by surface - mounted optodes, and 2) a recently proposed Interactive Brain Hypothesis that establishes a broad theoretical framework for two - person social neuroscience.
Not only is this a novel way to study basic biological mechanisms of these commonly targeted receptors inside the brain and individual neurons, but it's also a tool scientists can use to study specific effects of drugs in various regions of the brain.
Prior research had developed a number of new compounds making use of a novel drug discovery paradigm which begins with natural products extracted from plants; it then entails selecting synthetic derivatives which demonstrate efficacy in multiple assays testing protection against different factors of the nerve cell damage and death which take place in brain injuries and in age - associated neurodegenerative conditions.
We've been encouraged to think that creativity is a property of the «right brain,» but truly creative thinking involves using both sides of the brain to generate novel and appropriate solutions to problems by combining information and ideas from widely different domains.
Read our interview with David Morrell for Murder as a Fine Art, where I picked his brain about 19th - century novels, murder as an art form, drug use and more.
Lisa Cron is the author of Wired for Story: The Writer's Guide to Using Brain Science to Hook Readers From the Very First Sentence and Story Genius: How To Use Brain Science to Go Beyond Outlining and Write a Riveting Novel (Before You Waste 3 Years Writing 327 Pages That Go Nowhere).
Story Genius: How to Use Brain Science to Go Beyond Outlining and Write a Riveting Novel (Before You Waste Three Years Writing 327 Pages That Go Nowhere)
New treatments are being tested to tackle the crippling difficulties of vertigo, including a clinical trial of prosthetic ear implants and ear gene therapy, with initial work revealing novel aspects of brain anatomy linked to balance which could be used as targets for future treatments.
However, I am also interested in how novel techniques based on the measure of brain potentials can be used to probe the memory of criminal suspects.
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