«Here, we show how a common growth signaling pathway in cells can destroy one of
the brakes on cell division to allow cell division to move forward,» Emanuele said.
For example, a gene called p53, which normally acts as
a brake on cell division, turns out to be mutated or lost in about half of all tumours.
Not exact matches
The protein puts the immune system's
brakes on, keeping its T
cells from recognizing and attacking cancer
cells, said Dr. Antoni Ribas, the study's principal investigator and a professor of medicine in the
division of hematology - oncology at the David Geffen School of Medicine at UCLA.