The functional data provided from a limited series of
breast cancer cell lines does not allow generalizable conclusions to be drawn.
Not exact matches
This work is being
done in collaboration with Dr. Hasan Korkaya, assistant professor, Biochemistry and Molecular Biology at the Medical College of Georgia, who has developed drug - resistant
cell lines, and with
breast cancer clinicians.
Dr.
Done explains: «Most
breast cancer starts in the epithelial
cells lining the mammary ducts.
Whereas conditioned medium from ABL1 / ABL2 - depleted
breast cancer cells did not affect RANKL abundance in osteoblasts compared with the
cells treated with control conditioned medium (Fig. 5E), we found that conditioned medium from
breast cancer cells lacking ABL kinases increased OPG abundance in the osteoblast
cell line (Fig. 5F).
Those are
cells that were taken from nun many years ago that had
breast cancer and they propagated them and they
do a lot of the research on this
line of
cells that actually came from a nun that had
breast cancer called MCF - 7 estrogen dependent
breast cancer.