Sentences with phrase «breast cancer driver»
«Breast cancer driver, HER2, in 3 percent of lung cancers, study finds.»
https://www.sciencedaily.com/ Not exact matches
«In addition to having a higher prevalence of triple - negative breast cancers than Caucasian women — something that has been documented in previous studies — we found that African American women with breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor biology,» says Tanya Keenan, MD, of the MGH Cancer Center, lead author of the Cancer Center, lead author of the study.
The drivers, or causes, can be different across a variety of cancers, like lung or neck, or breast cancer, and can vary within each cancer.
Most breast cancers contain subclonal populations, many of which harbor driver alterations, and subclonal structure is typically remodeled over time, across metastasis and as a consequence of treatment interventions.
Careful examination of primary breast cancers often reveals multiple genomically distinct subclones that may contain driver alterations that follow spatial patterns of segregation.