Sentences with phrase «breast cancer progression»

Breast Cancer: CXCR4 plays an important role in breast cancer progression by enhancing tumor growth, tumor cell invasion, and metastasis to bone and lung.

Nagahashi M, Ramachandran S, Kim EY, Allegood JC, Rashid OM, Yamada, A, Zhao R, Milstien S, Zhou H, Spiegel S, and Takabe K. Sphingosine -1-phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis.

An Improved Syngeneic Orthotopic Murine Model of Human Breast Cancer Progression Breast Cancer Research and Treatment 2014 Oct; 147 (3): 501 - 12.

Genomic characterization of breast cancer progression.

To evaluate whether altered expression of the ABL genes is associated with breast cancer progression and metastasis, we examined the expression of ABL1 and ABL2 in normal and invasive breast tumor specimens using published TCGA (The Cancer Genome Atlas) data sets (14 — 16).

University of Miami School of Medicine Resistance to tamoxifen: a consequence of altered p27Kip1 regulation during breast cancer progression

The study, «AKR1B1 promotes basal - like breast cancer progression by a positive feedback loop that activates the EMT program,» which has been published in The Journal of Experimental Medicine, suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer.

HIF - 1 has been shown to regulate breast cancer progression.

In particular, I am developing methods to detect morphological changes in the extracellular matrix that accompany breast cancer progression.

Endogenous tRNA - Derived Fragments Suppress Breast Cancer Progression via YBX1 Displacement.

Escobar G, Moi D, Ranghetti A, Ozkal - Baydin P, Squadrito ML, Kajaste - Rudnitski A, Bondanza A, Gentner B, De Palma M, Mazzieri R, Naldini L. Genetic engineering of hematopoiesis for targeted IFN - α delivery inhibits breast cancer progression.

The team determined that because of the frequency of lesions, their association with spontaneous mammary cancer and the resemblance to human lesions, dogs may be the ideal model to study human breast cancer progression as well as prevention and treatment.

In truth, says Lacroix, unlike the melanoma it really was, «this particular metatastic behavior is rarely seen in breast cancer progression.»

Thus, downregulation of LARP7 correlates with breast cancer progression, metastasis, and poor prognosis.

These data confirm that LARP7 protein levels are also reduced during breast cancer progression, and thus suggest that LARP7 may play a potential tumor suppressor role in breast cancer.

Therefore, we have explored the role of the alpha2 beta1 integrin in cancer initiation and progression using a clinically - relevant, spontaneous mouse model, the MMTV - Neu model of breast cancer progression and metastasis.

As a next step, the researchers plan to further study the relationship between hot flashes and breast cancer progression by measuring the tamoxifen metabolites in breast cancer survivors.

«It has taken us years to assemble the clinical outcome database and tissue samples, generate the immunohistochemical biomarkers, gene expression profiles and analyse the data for this study — and we were delighted to find a definite link between alpha beta crystallin and breast cancer progression, which we hope will ultimately improve clinical outcomes.

Epithelial - mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression.

We are currently exploring this possibility and hope to elucidate the mechanism and relevance of the cycling hypoxia - selected cell population in breast cancer progression.

We have established a technique to generate syngeneic murine metastatic breast cancer model that mimic human breast cancer progression (Rashid OM et al, Breast Cancer Research and Treatment 2014).

The major two focuses of his Ph.D. study were to study the cellular and molecular mechanisms of prostate cancer metastasis and to study the effects of pomegranate derived natural products on prostate and breast cancer progression.

His laboratory has pioneered work on S100A7 and its role in breast cancer progression.

«Our findings provide compelling observational evidence for inverse associations between vitamin D levels and risk of breast cancer progression and death,» Song Yao and colleagues concluded.