«Ability to isolate, grow
breast tissue stem cells could speed cancer research.»
Not exact matches
Stem cells from breast milk can grow into many other kinds of human tissue, raising hopes of an ethical source of embryonic - like stem c
Stem cells from
breast milk can grow into many other kinds of human
tissue, raising hopes of an ethical source of embryonic - like
stem c
stem cells
Now scientists have shown that the
stem, or progenitor
cells, which should ultimately make healthy
breast tissue, can also have GT198 mutations that prompt them to instead make a perfect bed for
breast cancer.
After isolating a mammary
stem cell from mouse
breast tissue, molecular biologist Jane Visvader and oncologist Geoffrey Lindeman of the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, managed to grow a functional
breast, complete with milk - producing glands and ducts.
In theory, healthy
stem cells could also be incited to regrow
breast tissue after cancer surgery, offering an alternative to reconstructive surgery.
The treatment is promising enough that research teams around the world are developing similar
stem cell therapies that can target and eradicate cancers of the prostate, lung,
breast, skin and other
tissues.
When the researchers used fetal
breast tissue rather than adult
tissue from mice, they were able to pinpoint which
cells were
stem cells but the
cells would rapidly change when grown in a dish.
In the case of gene editing, Verma is creating induced pluripotent
stem cells (iPSCs) from patients by taking, for example, skin
cells of patients, coaxing them back into an early
stem cell state, and then providing conditions to make those
cells develop into more complex brain, lung, prostate and
breast tissues.
Cancer
stem cell markers are enriched in normal
tissue adjacent to triple negative
breast cancer and inversely correlated with DNA repair deficiency.
LA JOLLA — By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary
stem cells — those that can form
breast tissue — alive and functioning in...
Certain differentiated
cells in
breast tissue can spontaneously convert to a
stem -
cell - like state, according to Whitehead Institute researchers.
LA JOLLA — By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary
stem cells — those that can form
breast tissue — alive and functioning in the lab.
But, by focusing on
tissue obtained from mouse embryos, the Salk researchers were able for the first time to identify and isolate a sufficiently large number of fetal
breast stem cells to begin to understand how their GPS works.
I had a hunch based on this work that microRNA expression would be different in
breast cancer
stem cells than in more differentiated tumor
cells or normal
tissue and that it would change as the
stem cells differentiated to form a tumor.