Dr. Mack's research has focused primarily on the use of novel antitumor agents in human estrogen receptor negative breast tumor cells, and more recently, on the use of bioflavonoids in the regulation of estrogen receptor positive (ER +) and estrogen receptor negative (ER --RRB-
breast tumor cell proliferation.
Not exact matches
Collectively, these results suggest that Nrk negatively regulates the estrogen - dependent
proliferation of mammary epithelial
cells, the disruption of which leads to
breast tumors.
These NSC - secreted antibodies assemble properly, possess
tumor cell - binding affinity and specificity, and can effectively inhibit the
proliferation of HER2 - overexpressing
breast cancer
cells in vitro.
Tumor hypoxia is often linked to decreased survival in patients with
breast cancer and has been shown to induce specific molecular changes in
cells including changes that confer a more malignant phenotype such as increased
proliferation (3), survival (4), invasion (5), and metastasis (6).
(Source) Another study found lyophilized strawberries to inhibit oral tumorogenesis in hamsters (source), while a different study investigated the effects of strawberry extract on leukemia and
breast cancer
cells, and discovered the extract to inhibit
tumor proliferation by causing
cell death.