Sentences with phrase «breast tumor samples»

(B) ABL2 mRNA abundance in 61 normal samples compared with 532 invasive breast tumor samples in the TCGA database.

The homogenized fresh breast tumor samples have been represented for flow cytometric analysis using FACS calibur flow cytometer (Becton Dickinson, Sunnyvale, CA, USA) equipped with a compact air cooked low power 15 mwat argon ion laser beam (488nm), data analysis was conducted using DNA analysis program MODFIT (Topsham, USA).

Working in mouse models of breast cancer and breast tumor samples from patients, Longmore and his colleagues showed that a protein that sits on the surface of tumor cells, called DDR2, binds to collagen and activates a multistep pathway that encourages tumor cells to spread.

Not exact matches

«Shifting protein networks in breast cancer may alter gene function: Changes in gene function in tumor samples correlate with patient survival.»

They analyzed bacterial DNA found in breast tissue samples from 58 women who were undergoing lumpectomies or mastectomies for either benign or cancerous tumors, as well as from 23 healthy women who had undergone breast reductions or enhancements.

The team chose to compare breast tissue from healthy individuals with tumor samples taken from breast cancer patients — including both primary tumors that had not spread from the breast to other body sites, and highly aggressive, metastatic tumors.

Using all the existing data that was available, Andrechek, along with MSU doctoral student Daniel Hollern, analyzed 1,172 mouse mammary tumor samples from 26 different preclinical models and was able to compile one of the largest databases to show which strains of mice were best suited to study a particular type of human breast cancer.

The team conducted additional experiments in which mouse breast tumors were sampled to generate so - called organoids — spheres of cells that grow in three - dimensional culture.

The researchers studied 24 tumor samples from breast cancer patients after the samples were transplanted into mice.

As a next step, Guha, Avadhani and colleagues plan to extend this study to in vivo mouse models and will also investigate these mechanisms in tumor samples from human breast cancer patients.

The idea is to sequence 10,000 tumor samples for each of several common cancers, such as breast and prostate.

To further validate our result in clinical samples, we obtained primary tumor from patients with advanced breast cancer and the tissue was passaged once in nonobese diabetic / severe combined immunodeficient mouse without in vitro culture.

Thus, in a panel of breast cancer samples, we identified tumor cells that did not form part of the bulk tumor mass, but instead were interspersed within the adjacent stroma — as if forming the forefront of cancer cell invasion.

If you have metastatic breast cancer, join a nationwide movement of patients, doctors, and scientists by sharing your tumor samples, your medical information, and your voice.

Tissue specimens were obtained from 30 cases having IDC and from 10 cases were diagnosed with benign breast lesions in addition to 10 normal breast samples were taken from tissue adjacent to the tumors.

Tissue samples were obtained from patients diagnosed with breast tumor in the Department of Pathology, Medical Research Institute (MRI), Alexandria University, Egypt, during the period from February to August 2015.

She has obtained intramural support through the Vanderbilt Physician Scientist Development (VPSD) Award Program and a Cancer Center Grant Support (CCSG) Award to identify relevant tumor antigens / targets in breast cancer tumor samples.

Laser Light Test Reveals Spreading Cancer Cancer imaging and breast cancer experts used advanced microscopes equipped with tissue - penetrating laser light to develop a promising new way to accurately analyze the distinctive patterns of ultra-thin collagen fibers in breast tumor tissue samples and to help tell if the cancer has spread.

Because of small sample size, the changes in tumor - initiating cell number were not significant (P > 0.05), but these data are supportive of the in vitro findings and suggest that hypoxia may have a positive effect on the tumor - initiating cell population in ER - α — positive breast cancers and a negative effect in ER - α — negative tumors.

Although the differing effects of hypoxia reported here are in conflict with previously published data, where no contrasting effect was seen (18 — 20), our data was produced using 13 primary breast cancer samples, as well as established cell lines, and the opposing effects in hormone receptor — positive and negative tumors, measured using multiple in vitro and in vivo CSC assays, were consistent in all cases.

Through the analysis of breast cancer patient blood, lymph node, and tumor samples by high - dimensional flow cytometry and in vitro functional assays we hope to unravel some of the answers to these questions.

By performing tumor sample testing we can determine what type of breast cancer it is, and what subtypes of breast cancer are relevant to the case.

After all, the malignancy of a tumor or lump requires an analysis of the sample and there are sensitive areas like genitals and breasts that are best left to the hands of an expert.