Sentences with phrase «breast tumour»

D - Limonene — Suppresses * tumours, reduces * tumour size, prevention of mammary, liver, lung and other cancers [5], carcinogen removal, reduction * in breast tumour growth [6], inhibition of mammary carcinomas [7], breast carcinoma regression in both early and late stage development [8].

This is a benign breast tumour, which is painless and slow - growing.

Cheng C, Edin NF, Lauritzen KH, Aspmodal I, Christoffersen S, Jian L, Rasmussen LJ, Pettersen EO, Xiaoqun G, Bergersen LH (2012) Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells Cell Oncol (Dordr), 35 (3), 217 - 27 PubMed 22700320

ab16056 staining COX IV in breast tumour tissue sections by Immunohistochemistry (IHC - P - paraformaldehyde - fixed, paraffin - embedded sections).

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution Nature, 461 (7265), 809 - 813 DOI: 10.1038 / nature08489

The team found that most of the genetic changes in the original breast tumour were also present in the metastatic tumours, showing that the cancer cells spread late in disease development.

The team has studied the most common kind of breast tumour — estrogen - positive (ER +) and accounting for 80 % of breast cancer tumour cases — that is characterised by a long period of latency with no symptoms.

They gave the glowing version of the drug to a woman about to have her primary breast tumour surgically removed.

«The new discovery has given us an important link between the biochemical function of PTEN and its role in prostate cancer, and in some triple negative breast tumours for which treatment is currently limited.»

Inside many breast tumours are tiny granules of calcium.

Now, the researchers have discovered an alternative in a mouse model: in the case of breast tumours with a specific defect in DNA repair, the animals can be cured using already established, cheap chemotherapy drugs, if enough DNA damage can be inflicted on the resting tumour cells.

Each gene in the region is being studied to see whether it is abnormal in breast tumours.

In addition, they showed for the first time that these genes are often the same as those that are altered in breast tumours - when a tumour develops, the DNA within the cancer cells themselves mutates.

THE Pentagon is turning its attention from the war on communism to the war on cancer by adapting military technologies to detect breast tumours.

The findings provide insights into the causes of breast tumours and demonstrate that breast - cancer genomes are highly individual.

Dr Gathani said: «Much of the apparent excess of aggressive breast tumours in South Asian and Black women is simply because they are younger than White women.

The rodents experienced hormone imbalances and more and bigger breast tumours, earlier in life, than rats fed a non-GM diet, the researchers claim.

The control group without the vaccination developed breast tumours.

Intriguingly, previous research found that RASAL2 was lost in some of the luminal type of breast tumours, where it acts as a tumour suppressor.

TNBC is deadly because, unlike other types of breast cancers such as estrogen receptor (ER) positive or HER2 amplified breast tumours which have effective targeted therapy, TNBC tumours do not respond to targeted therapy.

With this finding, RASAL2 could be a new potential biomarker that is associated with the high risk of TNBC, rather than all types of breast tumours.

Early breast tumours show up on a mammogram long before they can be felt as a lump.

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups Nature DOI: 10.1038 / nature10983

«Patients» breast tumours can vary significantly in their biology over time.

The group went on to identify three key signalling networks that were represented by the bCSC DMR - associated genes; NFKB RB1 and TGFB1, and then analysed these networks in various breast tumours.

We examined the expression of Slc6a14 in breast tumours obtained from 4 - month - old PyMT - Tg female mice and in mammary glands obtained from age - matched wild - type female mice.

The rats were exposed to 1 of the chemicals utilized in the most commonly used HRTs in the US — a progestin known as MPA (medroxyprogesterone acetate), which is also the very same synthetic hormone which accelerates development of breast tumours.

Some synthetic hormones made use of in HRT accelerate development of breast tumours.

«[H] igh LDL receptor content in human breast cancer tissue seems to indicate a poor prognosis, suggest [ing] that breast tumours rich in LDL receptors may grow rapidly» in the body.

Not exact matches

Medical researchers have keenly studied the relationship between vitamin D and cancer in recent years, with evidence mounting that a lack of sunlight can contribute to tumours of the breast, prostate and colon.

A doctor exams mammograms, a special type of X-ray of the breasts, which is used to detect tumours as part of a regular cancer prevention medical check - up at a clinic in Nice, south eastern France January 4, 2008.

The chances of being cured of breast cancer have increased in recent decades, however if the tumour has metastasised, the disease remains essentially incurable.

The study has been tested in metastatic patients with different primary tumours such as breast, colon and lung cancer.

Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.

FGFRs work in an aberrant manner in 10 - 15 % of HER - 2 negative breast cancers, which could explain a greater the compound's greater anti- tumour activity compared to other compounds.

These results have important implications for the understanding of the mechanisms controlling tumour heterogeneity and the development of new strategies to block PIK3CA induced breast cancer.

The experimental drug nintedanib, combined with standard chemotherapy with paclitaxel, causes a total remission of tumours in 50 % of patients suffering from early HER - 2 - negative breast cancer, the most common type of breast cancer.

«We found that nearly one in four patients with small tumours are at risk of distant metastases and do benefit from chemotherapy,» said Dr Fatima Cardoso, senior author of the study, Co-Principal Investigator of MINDACT and Director of the Breast Unit of the Champalimaud Clinical Centre, Lisbon, Portugal.

Commenting on the results for ESMO, Dr Evandro de Azambuja, Head of the Medical Support Team, Academic Promoting Team, Jules Bordet Institute, Brussels, Belgium, said: «This study shows that it's not only tumour size that is important for breast cancer patients but also tumour biology.

Breast cancer patients who have radiotherapy targeted at the original tumour site experience fewer side effects five years after treatment than those who have whole breast radiotherapy, and their cancer is just as unlikely to return, according to trial results published in The LBreast cancer patients who have radiotherapy targeted at the original tumour site experience fewer side effects five years after treatment than those who have whole breast radiotherapy, and their cancer is just as unlikely to return, according to trial results published in The Lbreast radiotherapy, and their cancer is just as unlikely to return, according to trial results published in The Lancet.

High levels of the protein were also found in cultures of metastatic cells from tumours of the colon, breast, head and neck.

Cardiff University scientists have developed a novel anti-cancer stem cell agent capable of targeting aggressive tumour forming cells common to breast, pancreas, colon and prostate cancers.

Around 15 per cent of women with breast cancer have this form of the disease, in which tumour cells lack the three receptors that most drugs target.

A COMPOUND that slows the proliferation of triple - negative breast cancer cells in lab tests could lead to the first drugs to target this aggressive type of tumour.

According to Rottenberg, this new immunotherapy has been only modestly successful when used on other frequent tumours such as breast cancer - also, it results in side - effects and enormous costs.

Every year, hundreds of thousands of women aged between 40 and 74 are invited to undergo mammography to detect abnormal changes and tumours in the breast as early as possible.

The time needed for breast cancer metastases (secondary lesions caused by cells that have escaped from the original tumour) to develop varies between patients, and little is known about the mechanisms that govern latency (the dormant state of cells that have already spread through the body).

Around 70 % of all cases of breast cancer are oestrogen - receptor positive, meaning that the cancer cells have a particular protein (known as a receptor) that responds to the female sex hormone oestrogen, enabling the tumour to grow.

Lead author Moustafa Abdalla writes: «Almost all genomic studies of breast cancer have focused on well - established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells.»

There may also be opportunities to develop drugs that treat cancer by activating RYBP in tumours, including breast cancer.