Sentences with phrase «broad population studies»

Most broad population studies comparing lab workers with nonlab workers show little overall increase in the risk of pregnancy complications or birth defects, although one study showed a tendency toward low birth weights and shorter gestational lengths in cases where either parent worked in a chemical factory.

Not exact matches

«While we are disappointed CheckMate - 026 did not meet its primary endpoint in this broad patient population, we remain committed to improving patient outcomes through our comprehensive development program, including the ongoing Phase III CheckMate - 227 study exploring the potential of the combination of Opdivo plus [our other cancer immunotherapy] Yervoy for PD - L1 positive patients, and Opdivo plus Yervoy, or Opdivo plus chemotherapy in PD - L1 negative patients,» he added.

Hanna Granroth - Wilding, who led the study, said: «Our knowledge of disease in wild animals has tended to focus on the individual, but our study shows that we need to pay more attention to the broader consequences of disease to fully appreciate the role that it plays in wild populations, especially those whose numbers may be under threat.»

That broad - brush impression of radioactive contamination of the landscape isn't sufficient for population studies.

But she said the NHANES database is a broader data source than sources for studies that have found declines in obesity rates among smaller or segmented populations.

Although the new JNCI study did not analyze individual cell phone usage — preferring instead to take a broader look at the population at large — other research has examined subgroups of cell phone users to try to discern different trends among more frequent use.

«Our multi-ethnic exploration of innate and adaptive immunity highlights a remarkable level of sharing across human populations of genetic variation influencing immune function, while identifying interesting instances of genetic effects on immune function that are specific to a population,» said Nir Hacohen, PhD, MGH and the Broad Institute, study author.

The trick for researchers, Willems Van Dijk says, is to sift information from broad studies of large populations to identify behaviors and other influences on health that can be modified.

What's not clear from this study is how such damage might be affecting pteropod populations or the broader ecosystem.

«Our population in this trial also had a high response rate in the control group, so further studies are needed in broader populations to assess the efficacy of buprenorphine implants versus sublingual buprenorphine in other settings.»

This is the first study to show that sleep duration has increased among broad segments of the United States population (students 15 and older, people who are employed, and retirees) over this period.

Drug - resistant bacteria that usually attack only hospital patients may now have jumped into broader circulation in the general population, according to a study in tomorrow's Journal of the American Medical Association.

The study included more than 100,000 adults from the general populations of 17 countries, providing a broad sample of people that varied greatly in socioeconomic, geographic and demographic makeup.

A linkage study identifies only broad regions containing dozens or even hundreds of genes, whereas GWA studies often allow the association of a specific gene with a certain trait in the population.

That makes studying the genetics of specific indigenous groups vital for understanding risk factors that could be present in the broader Mexican population, says Xavier Soberón, head of Mexico's National Institute of Genomic Medicine (INMEGEN), who was not involved in the research.

«Our study suggests that highly polygynous, predominantly Maasai, villages do poorly not because of polygyny, but because of vulnerability to drought, low service provision and broader socio - political disadvantages,» said David Lawson, a population health lecturer at the London School of Hygiene & Tropical Medicine and lead author of the study published in the Proceedings of the National Academy of Sciences.

While the Mediterranean diet may have broad health benefits, its impact on cognitive decline differs among race - specific populations, according to a new study published in the Journal of Gerontology.

«It is [still] possible that a population of wolves remained relatively untamed but tracked human groups to a large degree, for a long time,» adds first author of the study Pontus Skoglund of Harvard Medical School and the Broad Institute.

Researchers leading the largest genomic tumor profiling effort of its kind say such studies are technically feasible in a broad population of adult and pediatric patients with many different types of cancer, and that some patients can benefit by receiving precision drugs targeted to their tumors» mutations or being enrolled in clinical trials.

«This study included a broader population, including both men and women, and with greater representation of African - Americans, and therefore may help describe the associations in populations beyond post-menopausal women who are primarily of European descent,» Dr. Bock said.

«We need to study a broader patient population to not only validate these findings but also determine other factors, such as inflammatory cytokines, that may contribute to the development of fatty liver in the IBD population.»

Gender, specific age, race and income did not influence the association; the study found that all demographic groups were equally affected by the link between social media and eating and body image concerns, indicating that preventative messages should target a broad population.

Trotti, Maness and colleagues didn't set out to dive into ME / CFS — they explicitly label this paper a pilot study, and the results say more about the «hypersomnolent» group of patients they have been seeing for the last several years, rather than the broader ME / CFS population.

Here at the Broad we combine human genetics, genetic and chemical screens, and population - based cohort studies to uncover the basic mechanisms of IBD, which may one day be used to develop effective treatments.

In a recent study by Helmsley grantee the Broad Institute of Harvard and MIT, researchers identified how the intestinal microbial population of Crohn's disease patients differs from that of individuals free of inflammatory bowel disease.

The researchers note that PRISM makes it easier to profile a broad range of cancers — not only rare cancers but also cancers from populations whose genetics are traditionally underrepresented in research studies.

Despite their lack of ethnic diversity, the men and women in the study represent a relatively broad cross-section of the population, Kennedy says.

In this article we will review creatines benefits, some important studies to back its efficacy, its broader applications, and the populations who will benefit most from its use.

al, 2005), studies of Internet dating that rely exclusively on students as participants may paint a biased portrait of Internet dating because their samples may enjoy greater natural access to dates than the broader population of Internet users looking for romance.

However, a more recent quasi-experimental study on a broader population finds no effects.

Boethel examines 64 studies on family and community engagement with diverse populations and organizes conclusions into 7 broad categories.

Part one of two studies confirms the broad variations of pre-kindergarten offerings across the state's largest school district, Houston Independent School District, as well as the impact high quality programs can have for disadvantaged populations in particular, using data for 50 of the district's 164 pre-kindergarten programs.

Two new studies from the Kinder Institute's Houston Education Research Consortium confirm the broad variations of pre-kindergarten offerings across the state's largest school district, Houston Independent School District, as well as the impact high quality programs can have for disadvantaged populations in particular.

Yet, since the technology PD K - 12 teachers received may have varied between districts, the findings of teachers» perceptions in this study were not meant to be generalized to the broader K - 12 technology - using teacher population regarding effective technology PD.

This reduced the incentive of districts to have a broad range of electives and even had negative impacts on science and social studies particularly in districts with high EL and free and reduced lunch populations.

As educators and lawmakers struggle to define the evolving role of education for the nation's gifted students, a new study suggests that some aspects of gifted education that have been appropriated to improve the achievement of a broader population of students may provide less of a boost than commonly thought.

This elegant study, published in Integrative Veterinary Care Journal and American Holistic Veterinary Medical Association Journal, should be an incentive for vaccine companies to address this issue, because vaccines are not without risk; veterinarians should push for a broader study to confirm these findings in a larger population.

A broad scale analysis of the evolutionary relationships of Urocyon lineages should be conducted because in this study, we found that eastern and western gray fox populations are more deeply diverged than the two currently recognized species of California Urocyon (S2 Fig.).

In a broader sense, a country with a population skewed toward males can experience more health problems, crime and potential for conflict, according to some studies.

Other aspects of global warming's broad footprint on the world's ecosystems include changes in the abundance of more than 80 percent of the thousands of species included in population studies; major poleward shifts in living ranges as warm regions become hot, and cold regions become warmer; major increases (in the south) and decreases (in the north) of the abundance of plankton, which forms the critical base of the ocean's food chain; the transformation of previously innocuous insect species like the Aspen leaf miner into pests that have damaged millions of acres of forest; and an increase in the range and abundance of human pathogens like the cholera - causing bacteria Vibrio, the mosquito - borne dengue virus, and the ticks that carry Lyme disease - causing bacteria.

These results are similar to those found in other sustained nurse home visiting studies, 1 14 although the intervention impacted on a broader range of domains of the home environment for this subgroup of women than has been reported previously.1 An increasing body of evidence from both animal and human studies suggests that stress in pregnancy has significant impacts on developmental and behavioural outcomes for children.29 While the mental development of children of mothers who were not distressed antenatally in both the intervention and comparison groups was comparable with the general population, children's development was particularly poor in the distressed subgroup in the absence of the MECSH intervention, suggesting that sustained nurse home visiting may be particularly effective in ameliorating some adverse developmental impacts for children of mothers with antenatal distress.

Strong gradients of association between childhood socioeconomic conditions and adult health have been consistently observed in a number of British, and other, populations at various stages within their life course, with outcomes considered including all - cause mortality, general health measures and specific causes of mortality and morbidity.1 — 10 This study continues to provide clear evidence for association between childhood socioeconomic deprivation and adult general health and mental well - being, even considered within a broad context of child well - being including other aspects of family background, health and development.

Research within clinical populations consistently finds that girls are more often abused than boys, although research focused on the broader population of community youth has not shown such gender differences in rates of physical maltreatment.72 Female offenders typically are abused before their first offense.73 Among girls in the California juvenile justice system, 92 percent report some form of emotional, physical, or sexual abuse.74 Self - reported victimization rates among boys in the juvenile justice system are considerably lower, though boys may be more likely than girls to underreport certain forms of abuse.75 Some studies report abuse rates for males between 25 percent and 31 percent, while others report rates of 10 percent for sexual abuse and 47 percent for physical abuse.76 Closer comparison reveals that delinquent males and females tend to report different types of traumas as well.

Further, existing research about mental health has rarely included a broad range of explanatory variables and no studies to date have included assessment of the mental health of carers, a factor that has been found in non-Aboriginal populations to be of critical importance.13

Moreover, Meier's statement addresses the broader population of «alleged» abuse — and the Kernic study expressly found the court was not even made aware of substantiated abuse in approximately 3/4 of cases.

Broad demographic studies of the flexible and ill - defined «fatherless homes» populations, which indicate complex and multi-causated reasons for the (actually small) negative outcomes suffered by a minority of children in these «single mother home» groups are twisted, baselessly, into the political rhetoric that children «need» or «benefit» from having two parents.

Childhood ADHD is strongly associated with a broad range of psychiatric disorders during adolescence: a population - based birth cohort study.

The mean age of the study population was similar to that of the broader population of Aboriginal and Torres Strait Islander mothers (25.1 years and 24.8 years, respectively), and both these populations were substantially younger than non-Indigenous Australian mothers (mean age, 29.7 years).

The fertility rate of the study population was 3.0 babies per woman, compared with 2.1 babies per woman for the broader population of Aboriginal and Torres Strait Islander mothers and a substantially lower rate of 1.76 babies per woman for all Australian women.21

The present study will investigate whether a broad set of predictors among mothers of toddlers is associated with relationship dissolutions throughout the next 17 years of parenthood, using data from the population based Norwegian TOPP study.