Sentences with phrase «broken cell machinery»

Not exact matches

Scientists longing to sneak a peek at the molecular machinery of living cells came one step closer to that goal in March with the creation of lenses that break the limits of current light microscopy.

While the PS is moving across the cell membrane and looking for a stronger chemical signal, only a few molecules of the breaking protein Cdc24 are present in the machinery.

To explore the role of DNA repair in translocation formation, the researchers inhibited key components of the DNA damage response machinery within cells and monitored the effects on the repair of DNA breaks and translocation formation.

«Our studies show that broken - down components of the nuclear transport machinery lead to traffic jams within brain neurons of essential information and eventually brain cell death,» says Grima.

Turning off the pathway can trigger cancer cells to self - destruct because the machinery used to untangle the DNA fails, meaning it is torn apart as the cell divides — ravaging and causing huge breaks in the code which lead to the cancer cells» demise.

One of the paper's co-authors, Hugh Willison, who studies GBS at the University of Glasgow in Scotland, says it's possible that something more subtle is happening: Like other viruses, the one that causes Zika hijacks a cell's own replication machinery to make new copies of itself, which then break out of the dying cell and infect neighboring cells.

They then showed that when the mice broke down disulfiram, its main metabolite, ditiocarb, forms a complex with copper that blocks the machinery that cells use to dispose of misfolded and unneeded proteins.

As described in a study posted online May 21 by Science magazine, the strategy uses tumor cells» own protein - chopping machinery to break down and dispose of proteins that drive cancer growth.

Like most machinery, the mitotic spindle can malfunction, and when it does, DNA can be broken or unevenly divided, errors implicated in the uncontrolled cell division of cancer.

They also gave the cells a correct copy of the A1At gene so that the cell's DNA repair machinery would use it as a template to heal the break.

A cell's own machinery will repair the break, and the repair can be directed to introduce new DNA sequences or to create deletions.

Essentially, this is the body's mechanism of getting rid of all the broken down, old cell machinery (organelles, proteins and cell membranes) when there's no longer enough energy to sustain it.