A total of 150 women with a history of two or more recurrent miscarriages and 20 fertile control women with no history of pregnancy losses had
buccal swabs taken for DNA analyses of 10 gene mutations [factor V G1691A, factor V H1299R (R2), factor V Y1702C, factor II prothrombin G20210A, factor XIII V34L, beta - fibrinogen -455 G > A, PAI - 1 4G / 5G, HPA1 a / b (L33P), MTHFR C677T, MTHFR A1298C].
Each child will have a
buccal cell
swab taken for measurement of their telomere length, and each adult will have a 15 mL of venous blood sample
taken for fasting glucose test, glycosylated haemoglobin test and full lipid profile test.