Khine uses Shrinky Dinks — a favorite childhood toy that shrinks when you bake it in the oven — to
build microfluidic chips to create affordable tests for diseases in developing countries.
With the three - year grant, Vanapalli and his collaborators Boyd Butler in the Department of Biological Sciences and Everardo Cobos at the Texas Tech University Health Sciences Center, will
build microfluidic devices that mimic blood flow to study how tumor cells move inside capillaries, how they squeeze through tight spaces, whether they are subject to fragmentation and how they become stuck.
The technique relies heavily on custom -
built microfluidic chips.
The other has
built a microfluidic chip that mimics lung function, resulting in a biologically relevant model for testing medicines for lung disorders or conducting toxicity screens for nanoparticles.
Not exact matches
Using the TEER - MEA chip, the researchers
built a beating vascularized Heart Chip in which human cardiomyocytes are cultured in one
microfluidic channel that is separated by a thin semi-permeable membrane from a second, parallel endothelium - lined vascular channel.
Prakash says that
microfluidics designers currently start from scratch with each project, but the bubble technology could offer common
building blocks for all
microfluidics designs.
Asking Catalan engineers to
build a vivarium based on
microfluidics in which to observe fruit fly larvae feeding behavior, the scientists demonstrated in subsequent experiments that D. melanogaster larvae are capable of making decisions that balance risk against benefit in the context of their food search.
I noticed this problem three years ago, when I was at a synthetic biology company where I
built some of these
microfluidic systems and mechanical machines that interact with them.
To study this barrier and determine why a lack of blood flow causes it to leak, the researchers
built a blood - vessel - on - a-chip model consisting of a channel lined with a layer of human endothelial cells surrounded by extracellular matrix within a
microfluidic device, which allowed them to easily simulate and control the flow of blood through a vessel and evaluate the cells» responses.
Building on the work that recently earned him a Nobel Prize in Chemistry, a Stanford University researcher used a
microfluidic single - molecule trap to capture individual molecules in solution without any perturbations due to surface attachment.
«Researchers
build liquid biopsy chip that detects metastatic cancer cells in blood: More effective than existing
microfluidic devices, the breakthrough technology.»
With little more than a conventional photocopier and transparency film, anyone can
build a functional
microfluidic chip.
By confining various liquids inside a hollow
microfluidic optomechanical (μFOM) resonator, researchers
built the first - ever bridge between optomechanics and
microfluidics.
«Our technology will provide significantly higher forces and faster impact cycles than have previously been possible, and by
building these tools onto
microfluidic devices, we can leverage a host of other on - chip diagnostics and imaging tools and can collect the cells after testing for longer - term studies,» said Valentine.