Sentences with phrase «built by cancer cells»

The unusual supply lines built by cancer cells may explain why some treatments fail and offer new targets for drugs.

Not exact matches

Vaz and Baylin say the results suggest that early epigenetic changes triggered by chronic cigarette smoke exposure can build up over time and make the airway cells increasingly sensitive to responding to mutations that initiate cancer.

The biomarker panel, enabled by discovery work of first author Jungsun Kim, PhD, a postdoctoral fellow in Zaret's lab, builds on a first - of - its - kind human - cell model of pancreatic cancer progression the lab described in 2013.

But their overriding interest in BPTES, says Slusher, was in how it works: by blocking the production of glutamine, an amino acid that acts as a building block of cells and is used frequently by pancreatic cancers to create more cancer cells.

Autophagy is a process by which cancer cells recycle essential building blocks to fuel further growth.

If we know, for example, that a cancer cell can be killed by deactivating a certain enzyme, researchers can build a detailed, 3 - D computer model of the enzyme to look for molecules that can go in and disable it.

The Lokey Stem Cell Research Building at Stanford University houses research conducted by the Ludwig Center for Cancer Stem Cell Research and Medicine.

«These findings build on a long history of work in our laboratory investigating mechanisms by which cancer cells respond to environmental stresses,» says Grant.

After being infused back into patients» bodies, these newly built cells both multiply and seek out a peptide expressed by the antigens NY - ESO - 1 and LAGE - 1 found in multiple myeloma cancer cells.

Silver says her lab will try to build such a cell that they can then implant into mammals to detect and report on the extent of harm caused by UV radiation, which damages DNA and is a risk factor in the development of cancer.

Scientists, led by Ottar Rolfssonat the University of Iceland, have built a mathematical model to examine the metabolism of breast epithelium — as the majority of breast cancers originate from these cells.

Researchers have built a model to investigate the metastasis of cancer by examining the metabolism of breast epithelial cells and look at the role of signaling.

«Cancer cells by definition have high mutation rates and genomic instability even at the very earliest stages, so you could imagine building a virus that could destroy even the earliest lesions and be used as a prophylactic,» says O'Shea.

These changes are necessary for cancer cells to meet the combined biomass and energy demands for growth and are only satisfied by increased capture and synthesis of cellular building blocks such as sugars, fats, and proteins.