Sentences with phrase «by a bone disease»

Not exact matches

Did you know... that three daily servings of low - fat or fat - free milk and milk products every day are part of a healthy, balanced diet by helping deliver nutrients, promoting bone health, and reducing your risk of certain diseases?

Gardeners would be well - advised to bone up on pest - and disease - control techniques and not take lightly the idea that some pest insects can wreck an otherwise spectacular summer by demolishing target plants.

A rare genetic disease leaves its victims debilitated by transforming soft tissue cells into bone cells, creating a strange second skeleton.

The work was on the role of interleukin - 1 in the pathology of graft - versus - host disease (GVHD), the mechanism by which the new immune system, which a patient receives as a bone marrow transplant, attacks the patient's body following the transplantation.

A medical doctor (of human patients), Rothschild is often sought out these days by paleontologists for his observations about the diseases revealed in bones (the dinosaur kind)-- and the subsequent deductions about how these long - extinct creatures might have lived.

The researchers also examined skin slices from two patients with another form of nerve disease called AL amyloidosis, caused by a bone marrow disorder.

Jayden had rickets, a Dickensian disease caused by a shortage of vitamin D, making his bones abnormally weak and vulnerable to damage.

Human hematopoietic stem and progenitor cells (HSPCs), derived from bone marrow, have become a primary vehicle for efforts to replace or regenerate cells destroyed by a variety of diseases.

At long last, paleontologists are giving it a diagnosis: septic arthritis, a bone disease that often develops when an injury is followed by infection.

The team led by Hajishengallis and Moutsopoulos noticed that gum disease and bone loss continued unchecked even when LAD patients were given antibiotics or had their plaque removed.

The goal of the ongoing project is to read the history written in these bones: when and where these people were born, what they ate, what diseases they suffered and died from, and how their health varied by social class and over time.

«The new FOP model already has shed light on the disease process in FOP by showing that the mutated gene can affect different steps of bone formation,» Hsiao said.

The disease model, described in a new study by a UC San Francisco - led team, involves taking skin cells from patients with the bone disease, reprogramming them in a lab dish to their embryonic state, and deriving stem cells from them.

He notes that the mummy's teeth are surrounded by pitted bone — evidence of painful gum disease, probably the result of a diet rich in meat and dairy but lacking in fruits and vegetables.

«We found that harmine, likely by interacting with DYRK1A, increases levels of other known drivers of cell division,» said Peng Wang, PhD, Assistant Professor of Medicine, Endocrinology, Diabetes, and Bone Disease at the Icahn School of Medicine and first author of the paper.

Another risk posed by short stature is that it can trigger other diseases, such as bone dysplasias, congenital heart disease, asthma or diabetes and genetic disorders such as Turner's or Down syndrome, hypothyroidism and growth hormone deficiency.

Paleopathologists can also calculate growth rates by measuring bones of people of different ages, examine teeth for enamel defects (signs of childhood malnutrition), and recognize scars left on bones by anemia, tuberculosis, leprosy, and other diseases.

High levels of bone destruction and reduced bone density caused by excessive osteoclasts are characteristic of osteoporosis, a common bone disease in which bones become fragile and susceptible to fracture.

Compared to the hunter - gatherers who preceded them, the farmers had a nearly 50 per cent increase in enamel defects indicative of malnutrition, a fourfold increase in iron - deficiency anemia (evidenced by a bone condition called porotic hyperostosis), a theefold rise in bone lesions reflecting infectious disease in general, and an increase in degenerative conditions of the spine, probably reflecting a lot of hard physical labor.

Myelofibrosis is a rare disease of the bone marrow, in which the bone marrow is replaced by connective tissue.

By receiving transplants of bone marrow cells along with the new kidney, four of five transplant patients with end - stage renal disease were able to stop taking immunosuppressive drugs within about one year after surgery.

Hosts infected by viruses found new uses for the genetic material the agents of disease left behind; metabolic enzymes somehow came to refract light rays through the eye's lens; mammals took advantage of the sutures between the skull bones to help their young pass through the birth canal; and, in the signature example, feathers appeared in fossils before the ancestors of modern birds took to the skies.

Because bone marrow, colon, and liver are significantly different tissues, the investigators believe the pathway by which SW033291 speeds tissue regeneration is likely to work as well for treating diseases of many other tissues of the body.

Other work was intended to examine the link between radiation exposure and disease by measuring tissue levels of strontium - 90 and other elements; one strontium - 90 project, for example, examined bones taken from more than 3000 people between 1955 and 1973.

Periodontal disease causes distinctive proteomic changes in the dentition and is characterized by chronic inflammation resulting in tooth and bone loss.

The study, led by Darja Marolt, PhD, a NYSCF - Helmsley Investigator and Giuseppe Maria de Peppo, PhD, a NYSCF Research Fellow, and published in the Proceedings of the National Academy of Sciences, represents a major advance in personalized reconstructive treatments for patients with bone defects resulting from disease or trauma.

«I envision a treatment that uses a precise combination of sclerostin antibodies to grow new bone, followed by bisphosphonates to lock in that bone growth,» said Michelle Caird, associate professor of orthopaedic surgery who specializes in brittle bone disease.

According to cardiologist Stefanie Dimmler at the University of Frankfurt in Germany, degraded telomeres might cause heart disease by impeding the ability of cells from the bone marrow to repair damaged parts of the arterial walls.

As the disease progresses, a person's ability to move can be severely limited by the damage done to the cartilage and bone in the joints.

While most cases of osteoporosis are caused by normal aging, another leading cause of the bone - loss disease is a condition called hyperparathyroidism, in which the parathyroid glands release an excessive amount of a hormone that regulates the body's calcium levels.

Other possible symptoms of the disease, which is usually caused by different mutations of the JAGGED1 gene, are deformities of the eyes or bones, and sometimes growth disorders.

Failure to produce new bone marrow can be caused by disease, trauma, or some cancer treatments, and can lead to a significantly higher risk of infections, and the need for blood transfusions.

Other areas of medicine have used this approach to define disease processes using biomarkers, for example: bone mineral density, hypertension, hyperlipidemia and diabetes are defined by biomarkers.

The therapy is approved by the U.S. Food and Drug Administration for relapsed or treatment - resistant Hodgkin lymphoma, and it is commonly prescribed to patients whose disease has progressed after autologous stem cell transplant, a procedure that replenishes the bone marrow with the patient's own healthy stem cells after therapy.

Osteoporosis, a progressive bone disease characterized by decreased bone mass and an increase in fractures, affects over 200 million people worldwide.

FOP is a severely disabling musculoskeletal disease characterized by extensive formation of endochondral bone within soft connective tissues.

PEOPLE whose jawbones have been eaten away by periodontal disease could one day be helped by inserting grafts of specially treated cattle bone to fill in the missing sections.

It is similar to that taken by cardiologist Arshed Quyyumi and colleagues with peripheral artery disease: use a growth factor (GM - CSF), which is usually employed for another purpose, to get the bodyâ $ ™ s own regenerative agents to emerge from the bone marrow.

Some of our core facilities are partially funded by the National Institutes of Health (NIH), Cancer Center Support Grant (CCSG), the Cancer Prevention Research Institute of Texas (CPRIT) or the Bone Disease Program of Texas (BDPTx).

Molecular mechanism underlying diseases (conformational diseases, cystic kidney disorders, neuromuscular diseases, inflammation, iron - related diseases, disorders of human reproduction, osteoporosis and bone diseases) are being investigated by many groups with robust animal and cellular models and patients» biological samples.

Led by Waisman Center and College of Agricultural and Life Sciences investigator Denise Ney and her graduate student Bridget Stroup, the study represents the first human clinical trial to compare how different PKU - specific diets affect the bone health of people living with the disease.

While the origins of BSE remain obscure, one possibility is that the cattle developed the disease by being fed meat and bone meal contaminated with prions from the sheep with the disease, scrapie.

This new knowledge has paved the way for the therapeutic transfer of stem cells not only for the treatment of hematopoietic diseases by bone marrow transplantation â $» first attempted by E. Donnall Thomas, one of this bookâ $ ™ s editors, in 1957 â $» but also for the treatment of many other disorders.

Adult stem / progenitor cells are present in many organs and tissues, e.g., bone marrow, teeth, heart, gut, kidney and liver, and remain quiescent for long period of time until activated by a disease or injury trigger.

Myelodysplastic Syndromes (MDS) are diseases of the blood and bone marrow, characterized by low blood counts.

Allogeneic stem cell transplantation to leukaemic patients, in which the patient's own diseased bone marrow is replaced by healthy donor material, is one of the best - established and most effective immunological therapies.

All of our materials are written in plain language and reviewed by highly respected and recognized medical doctors who are experts in bone marrow failure diseases.

Rheumatoid arthritis (RA) is a disease mainly defined by its clinical features of chronic inflammation in joints associated with bone and cartilage destruction.

Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated as a secondary outcome, supported by observational data as well as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast cancer was designated as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases; endometrial, colorectal, and other cancers; and other fractures.3, 6,9

Aplastic anaemia is a rare, and potentially fatal, disease of the blood, by which the bone marrow is unable to generate blood cells at the appropriate pace.