Signaling
by molecules called prostaglandins plays a key role in the body's response to inflammation.
This enables them to leave the vessels and establish metastases, a process facilitated
by a molecule called DR6.
However, once opiate addiction had developed, the scientists observed a functional switch to a separate molecular memory pathway, controlled
by a molecule called calmodulin - dependent kinase II or «CaMKII.»
When stimulated
by molecules called fibroblast growth factors, this receptor, known as FGFR3, prevents the cells from maturing and impedes bone formation.
By analysing human endometrial cells implanted in mice, Jan Brosens at the University of Warwick, UK, and his colleagues discovered that the four - day window is regulated
by a molecule called interleukin - 33.
Finally, their activity was boosted
by a molecule called co-enzyme A.
Tight junctions, regulated
by a molecule called zonulin, as well as by conformational changes in the proteins occludin and claudin, are dynamic intercellular structures that modulate the trafficking or passage of macromolecules from the intestinal lumen to the submucosa and into systemic circulation (Fasano, 2012).
Cholesterol runs through the blood carried
by molecules called lipoproteins.
Not exact matches
They then sound the alarm
by producing small hormone - like
molecules called cytokines and chemokines.
What Boger wants is to create a better way to develop drugs: through a process
called structure - based design in which scientists build up a new drug, atom
by atom, after determining the type of
molecule that might interrupt the disease process.
Oh, the Calvinists could make perfect sense of it all with a wave of a hand and a swift, confident explanation about how Zarmina had been born in sin and likely predestined to spend eternity in hell to the glory of an angry God (they
called her a «vessel of destruction»); about how I should just be thankful to be spared the same fate since it's what I deserve anyway; about how the Asian tsunami was just another one of God's temper tantrums sent to remind us all of His rage at our sin; about how I need not worry because «there is not one maverick
molecule in the universe» so every hurricane, every earthquake, every war, every execution, every transaction in the slave trade, every rape of a child is part of God's sovereign plan, even God's idea; about how my objections to this paradigm represented unrepentant pride and a capitulation to humanism that placed too much inherent value on my fellow human beings; about how my intuitive sense of love and morality and right and wrong is so corrupted
by my sin nature I can not trust it.
Thus, at the lowest level, electrons tend to unite and converge in the atom; atoms converge
by molecularization, crystallization;
molecules unite
by polymerization; cells unite
by conjugation, reproduction, association; nerve ganglions concentrate and localize to form a brain
by what might be
called a process of cephalization; the higher animal groups form colonies, hives, herds, societies, etc.; man socializes and forms civilizations as foci of attraction and organization.
An elementary step that will be important for our purposes involves the reaction of one
molecule,
called Y, with two
molecules of another kind, denoted X. To the extent that this reaction is elementary, the reaction velocity doubles as the concentration of Y doubles, but increases
by a factor of four if the concentration of X doubles.
Scientists Elizabeth D. Prescott and David Julius of the University of California, San Francisco, announced they had identified a lipid
molecule called PIP2 that plays a crucial role in controlling the strength of the burning sensation caused
by capsaicin.
For lactose to be digested, these two sugar
molecules must be separated
by an enzyme
called lactase.
The
molecule —
called VCP — is a component of the infected cell rather than a substance produced
by the virus itself.
On Earth, the brightest auroras (the high - altitude glows often
called the northern and southern lights) are generated when electrons in outer space near Earth are accelerated
by large electrical potentials, or voltages, along the lines in our planet's magnetic field and slam into gas
molecules in the upper atmosphere above polar regions.
The researchers looked for 200 types of immune - signaling
molecules called cytokines and identified 64 that were different, usually more abundant, in the eyes affected
by NIV.
Such reactions are specifically catalyzed
by the large protein
molecules called enzymes, many of which have now been purified and also studied.
Now 24, he is a first - year graduate student in the department of cellular and structural biology at the University of Texas Health Science Center in San Antonio (UTHSCSA), where he is studying the role of oxidative damage — the wear and tear inflicted upon the cell
by toxic
molecules called free radicals — in the aging process.
Gene expression is the process where information stored as DNA is converted (transcribed)
by enzymes into related
molecules called RNAs, and then into proteins that make up the body's structures and signals.
Fischetti and his colleagues used a phage - encoded
molecule to identify a bacterial target enzyme
called 2 - epimerase, which is used
by Bacillus anthracis to synthesize an essential cell wall structure.
Led
by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), the retrospective study suggested that a pattern of
molecules called microRNA (miRNA) in tumor cells might predict patients» response to radiation therapy.
MOFs are microscopic - scale porous crystals engineered from metal ions bound together
by organic
molecules called ligands.
A team of scientists led
by Dr. Martin Zeppenfeld from the Quantum Dynamics Division of Prof. Gerhard Rempe at the Max Planck Institute of Quantum Optics in Garching has now made a virtue of necessity: the so -
called optoelectrical Sisyphus technique, developed in the group, exploits the polarity of formaldehyde
molecules, while reaching temperatures as low as 420 micro-Kelvin.
Oxidative stress is damage to the body caused
by an accumulation of unstable
molecules called free radicals.
Separate work
by Colm Cunningham and his colleagues at Trinity College Dublin in Ireland has shown that interleukin - 1 beta is a likely neuron - killing culprit, along with other inflammatory
molecules called prostaglandins (Journal of Neuroscience, doi.org/sdr).
The scientists have observed that the formation of an adenoma in the colon is accompanied
by an increase in the production of a
molecule called BMP (bone morphogenetic protein).
In what Grashorn
calls a «serendipitous discovery», his team has worked out that these signals are generated
by speeding electrons produced when cosmic rays collide with
molecules in the air.
To help visualize these brief, transient interactions, Li and Wahl turned to a
molecule called luciferase, an enzyme that generates bioluminescence of the sort used
by fireflies to make their bodies glow.
The company's Single -
Molecule, Real - Time (SMRT) DNA sequencing technology starts
by chopping DNA into pieces, then isolates each piece in an observation chamber
called a zero - mode waveguide.
Lee, Coban, and colleagues suspected that the culprit was chemical waste released
by the parasites, including the residue of digested hemoglobin, a
molecule called hemozoin.
He uses a technique
called diffusion spectrum imaging, which traces neural connections
by following water
molecules as they diffuse along axons.
Funded
by the U.S. Department of Energy, researchers from the Catalysis Center for Energy Innovation developed a new chemical process to combine fatty acids from soybeans or coconut and sugar - derived rings from corn to make a renewable soap
molecule called Oleo - Furan - Surfactant (OFS).
When G - CSF activates its receptor, it ultimately activates proteins
called STATs; the team engineered the cells to churn out the light - generating protein luciferase, which would be turned on
by the STAT
molecules.
This seems to be triggered
by the collective release of a signalling
molecule called interferon - beta, although what causes this is unclear.
By modeling the reaction, they concluded that the initial energy burst could come from ultraviolet (UV) light, which produces energetic oxygen
called singlet oxygen when it breaks up water
molecules.
In 1996, Peter Klein of the University of Pennsylvania discovered that one of lithium's biological activities was inhibiting GSK - 3, an enzyme that modifies other proteins
by attaching phosphate
molecules, a process
called phosphorylation.
The research published in the journal Metabolism, examined a
molecule called Lysyl oxidase (LOX) which regulates scarring
by making tissue stiffer.
The study, conducted
by two teams at Duke University and appearing online Dec. 1 in the journal Neuron, is the first to connect autism to one of the most well - studied pain
molecules,
called TRPV1 (transient receptor potential ion channel subtype V1), which is a receptor for the main spicy component of chili peppers.
The researchers targeted mTOR with an experimental drug based on a prototype first designed
by Shokat, a chemist and an expert in designing
molecules to target this type of protein,
called a kinase.
These agents are
called disaccharide derivatives, and they mimic a class of natural
molecules known as rhamnolipids, which are produced and secreted
by the bacterium itself.
The team found that lithium delays aging
by blocking GSK - 3 and activating another
molecule called NRF - 2, which is found in worms, flies and mammals (including humans) and is important for defending cells against damage.
But the flowers that Gaskett studies,
called tongue orchids, can produce a
molecule that precisely mimics the pheromone made
by the females of the species Lissopimpla excelsa, commonly known as dupe wasps.
In a study published in the journal Nature Medicine, the researchers reported that the tumor - suppressing protein AIM2, or Absent in Melanoma 2, helps prevent colon cancer
by restricting a signaling
molecule called Akt.
The building blocks, says Stupp, a chemist at the University of Illinois in Urbana - Champaign, are
molecules called rodcoils, which he did build himself
by conventional chemical methods.
Pirate is a member of a class of chemicals
called pyrroles, which kill
by tampering with several enzymes needed to manufacture the energy storage
molecule ATP in cells» mitochondria.
The engineered protein has two ends: one activates T cells
by binding to a surface
molecule called the CD3 receptor, and the other — based on an antibody
called VRC07 — powerfully binds to more than 90 percent of HIV strains.
A team of researchers led
by Julie Y. Djeu, Ph.D., associate center director of education and training at Moffitt, discovered that TGF - β produced
by tumor cells causes NK cells to make high levels of a
molecule called microRNA - 183 (miR - 183).
The activity of the latter protein is known to be blocked
by a small
molecule called Nutlin - 3.