As Columbia University neuroscientist Eric Kandel and others have shown, neurons respond to stimulation
by altering their activity and connectivity, remodeling the architecture of the brain.
By altering the activity of mitochondria — the powerhouses that provide cells with energy — it forces the body to burn fat.
They could also help discover a new way to fight addiction in both adolescents and adults, for example
by altering the activity of eIF2α in the brain.»
In some cases, they help regulate inflammation
by altering the activity of messaging molecules within our body's inflammatory system.
Not exact matches
If the regulator finds potential criminal
activity by either the borrowers or the banks, it could also refer the matter to prosecutors for further investigation,
Alter said.
Included in my
activities was a read of The Defining Moment: FDR's Hundred Days and the Triumph of Hope
by Jonathan
Alter.
If the recent deterioration in business sentiment is to have a significant effect on real
activity, it would do so
by altering firms» investment and employment plans.
«Re-entry», as Edelman states, «provides the critical means
by which the
activities of distributed multiple brain areas are linked, bound, and then dynamically
altered in time during perceptual categorization.
The March 12, 2015 issue of Nature magazine contains an essay — not an original thesis, rather a summation —
by two English geographers entitled «Defining the Anthropocene,» the subject of which is whether (and starting when) human
activity has so
altered the global environment as to constitute a new geologic age: the Anthropocene Age, as successor to the 11,000 - year Holocene Epoch that is itself part of the larger 2.6 million year - old Quaternary Period (or Great Ice Age).
Perception is certainly an
activity for the Greek, but it also essentially involves passivity, i.e., being acted upon and
altered by the entities of the physical world.
Many thoughtful citizens, including eminent scientists, oppose the deciphering and
altering of the human gene structure, and are appalled
by the proposed commercial uses of knowledge gained from such
activities.
Our understanding of sex in the narrower sense of genital
activity and in the wider sense of relationship with others has been so
altered in recent years that the assumed fixity of thought in this area, with reference to auto - erotism, homo - erotism, and hetero - erotism, along with the related fixity which has been traditionally accepted in respect to judgements upon the right or wrong ways of sexual expression, has been shown to be indefensible
by any intelligent standards.
Fifty percent said they were surprised
by how much their daily
activities have
altered.
Two of the Purdue studies [36,37] suggested that it might be possible to reduce risk of brain trauma
by gradually increasing the amount of contact in the football pre-season to allow time for players» brains to adjust, and one,
by finding that players who sustained more than 50 hits per game, were much more likely than those who sustained fewer hits to be «flagged»
by ImPACT and / or fMRI results as having neurocognitive deficits or
altered brain
activity, suggested that players be limited to a certain number of plays per game (a hard rule to implement, given the prevalence of two - way players in the high school game).
These mechanisms may include
altered systemic inflammation as a consequence of depression, or even the role of lifestyle behaviors such as physical
activity or nutrition, which are typically worsened
by depression, and which may place an individual at risk for psoriatic arthritis.
The discoveries also hint at ways to hold on to youth
by altering mitochondrial
activity.
The researchers further found that miR - 486 is itself regulated
by the tumor - suppressor gene p53, the most frequently
altered gene in human cancers, and that
activity of miR - 486 is partially dependent upon functional p53.
By quelling
activity in a part of the brain that evaluates threats and plans responses, researchers can
alter peoples» views on immigrants and religion, The Daily Beast reports.
«Because many broadly expressed genes that play key roles in essential cellular functions are under the control of cell - specific enhancers, the ability to affect enhancer function
by knocking down eRNAs could potentially provide a new strategy for
altering gene expression in vivo in a cell - specific manner,» said Glass, noting that in his research, anti-sense oligonucleotides were developed in conjunction with Isis Pharmaceuticals, which suppressed enhancer
activity and reduced expression in nearby genes.
In fact, in a world that has been dramatically
altered by human
activity, many could be important allies in rebuilding healthy ecosystems.
Researchers predicted and found that
by altering brain
activity in this brain area, they could change how subjects punished hypothetical defendants without changing the amount of blame placed on the defendants.
«
By combining in vivo multiphoton microscopy and in vivo electrophysiology, our lab is better able to visualize how cells move and change over time in the living brain and explain how changes in these glial cells
alter the visually evoked neural network
activity,» says Kozai.
More analysis showed that
altering Cdk5
activity changed the level of several groups of genes that were also affected
by aging, including those that control immunity, energy, and antioxidant
activity.
By boosting pat - 10
activity, they were able to cure worms that had been
altered to express the Huntington's disease gene, and also extend the lifespan of normal worms.
Today's forests have been greatly
altered by human
activity and face increasing threats from drought, insect infestations and fire.
Burwell, Ho, and the group used this capability to
alter activity in the PER
by pulsing the light into that part of the brain at different frequencies.
Variations in N - CAM
activity thus do not occur
by changes in the amino acid sequence that
alter the specificity of binding.
Scientists think that changes in crotonylation can
alter gene
activity by turning genes on or off.
The good news is that WWOX belongs to a family of proteins that have enzyme
activity - this means WWOX
activity can be
altered by targeting the enzyme.
The team found that the mutations
alter the function of potassium channels
by reducing the
activity of these channels.
The researchers showed these relationships between ecRNA production and gene
activity in neurons included genes whose expression is
altered by neuronal
activity and genes implicated in developmental and neurodegenerative disorders.
When the researchers
altered the animals» eating patterns
by feeding normal mice only during the light cycle (a mouse's night), the numbers, types, and
activity of the bacteria shifted as well.
The remaining species showed shorter flower duration, in one case
by nearly 19 days, possibly due to accelerated soil drying,
altered pollinator
activity or other factors.
As well as generating mutations
by inserting themselves into and disrupting genes, retrotransposons can
alter gene
activity if inserted into adjacent regulatory regions of DNA.
Buzsáki acknowledges there are many possible routes
by which conventional TES could
alter neural
activity indirectly or over longer time scales.
The research team led
by Han used high - throughput techniques to
alter the
activity of dozens of genes in flies» hearts simultaneously in order to validate genes that cause heart disease.
Once the bacterial cell signaling protein cagA reaches the host cytosol, it is capable of
altering subsequent generations of progenitor cells, leading to the development of cancer through changes in mitotic
activity, apoptosis, cellular assembly, and signaling.26 Although it should be noted that while the presence of the cagA protein doubles the risk of gastric cancer, cagA - negative strands also increase the risk of distal gastric cancer.27 Additional H pylori virulence factors include babA2, which encodes bacterial adhesion with gastric epithelial cells, and vacuolating cytotoxin A, which is encoded
by the gene vacA.28, 29 H pylori strains carrying some combination of the babA2, cagA, and vacA genes were associated with the highest risk of developing intestinal metaplasia.
Next steps: The team wants to understand how much farther the
activity and stability of immobilized enzymes can be enhanced
by rationally
altering the enzymes and the nanopore sizes and functional groups.
Now it seems that this memory can be
altered by meddling with the electrical
activity of the animals» cells.
At the University of Utah, a team of scientists led
by Professor Scott Anderson found that the size of the palladium clusters strongly
alters their catalytic
activity.
The new data — from animals and human cells — show that the vapors released
by e-cigarettes can
alter the
activity of genes.
«It's a more complicated picture, but broadly it means that there are going to be winners and losers in the oceans as its chemistry is modified
by human
activities — this could have the effect of
altering major ocean ecosystems on which both we and a large part of marine life depend.»
Through a series of tests, the team found that mutations were
altering gene
activity through two distinct mechanisms — both in the same «direction,»
by disrupting the gene.
This text covers topics ranging from plant genome structure and the key control points in how genes are expressed, to the mechanisms
by which proteins are generated and how their
activities are controlled and
altered by posttranslational modifications.
In a pioneering study, he applied these tools to a genome - wide study of disease - related changes in the epigenome — the layer atop the genome that controls gene
activity and is
altered by the environment — of immune cells isolated from patients with asthma.
A single poor transcript could therefore have devastating consequences, not just
by directly
altering a cell's enzymatic
activity but through a domino effect that leaves other, unrelated proteins unable to function right.
Cells respond to diverse stimuli
by altering gene
activity.
In the book Relaxation Revolution: The Science and Genetics of Mind Body Healing, author Herbert (Benson) discusses how breathing can literally change the expression of genes, and that
by using your breath, you can
alter the basic
activity of your cells with your brain.
One of the definitions of «virgin» in the Merriam - Webster pocket dictionary is: «fresh, unspoiled; especially: not
altered by human
activity.»
Sulforaphane is a potent antioxidant which has been found to boost the detoxification
activity of liver enzymes
by altering genetic expression.