Sentences with phrase «by an unknown gene»

That still leaves a fair proportion of individuals with disease caused by an unknown gene.

Not exact matches

Changes in key genes clearly define four previously unknown conditions within the umbrella diagnosis of schizophrenia, according to a study led by researchers from NYU Langone Medical Center published online April 28 in EBioMedicine, a Lancet journal.

Using a genome - wide genetic screen, Dr. Gelman and colleagues identified a previously unknown metastasis suppressor — the FOXO4 protein, which belongs to a family of genes that are produced by all human cells.

By following the DNA - transfer, scientists for the very first time showed an unknown mechanism called carry back in which pathogens were able to snatch genes from far - related bacteria via the carry back mechanism.

By working closely with the KhoeSan, a group of populations indigenous to southern Africa, the researchers have found that the genetics of skin pigmentation become progressively complex as populations reside closer to the equator, with an increasing number of genes — known and unknown — involved, each making a smaller overall contribution.

Phevor solved the mystery by identifying the disease and finding an unknown gene mutation that caused it.

The March of Dimes Prematurity Research Center — Ohio Collaborative, launched in 2013, is responsible for the gene identification component of the network of five Prematurity Research Centers nationwide established by the March of Dimes to identify the unknown causes of preterm birth.

The team eliminated three of the four known starch synthases by inserting backward copies of the genes for each one into the potato genome, which, through an unknown mechanism, interferes with the translation of the nearby normal gene.

By focusing on this shortlist of genes, researchers can quickly discover genes previously unknown to be related to tissue structure.

By looking at the gene expression profile in single cells, the researchers were able to identify previously unknown transient states that typified the progression from precursor to more - specialized cells.

These mutant kinases are attractive therapeutic targets, as demonstrated by the efficacy of imatinib in BCR - ABL — positive chronic myelogenous leukemia (CML), 5 as well as in MPD associated with activating alleles involving PDGFRA or PDGFRB.2, 6,7 In addition, activating mutations in the FLT3 receptor tyrosine kinase are the most common genetic event in acute myeloid leukemia (AML), and specific inhibitors of the FMS - like tyrosine kinase 3 (FLT3) have entered late - stage clinical trials.8 Although mutations in tyrosine kinases and in other genes have been identified in a subset of MPD and AML, in many cases the genetic events that contribute to the molecular pathogenesis of these diseases remain unknown.

«By making a digital tomato, we can start to infer the function of unknown genes,» said Rose.

Now a research team led by Broad Institute Imaging Platform director Anne Carpenter and postdoctoral fellow Mohammad Rohban has shown that a high - throughput, computerized imaging technique for studying morphology, called Cell Painting, can provide insight into the cellular roles of genes or disease - linked gene alleles whose function or impact is unknown.

In a person who has been burning carbs for decades, not getting to the point where the ever need to burn fat, there are scores of known enzymes and likely many unknown that need to be manufactured from scratch by genes that may also themselves need to be revved up again in terms of their expression.

Eigenberg returned to the same genre amid a cast of unknowns with the 2007 film The Trouble with Romance, directed by Gene Rhee.

Occasionally it misses by a fairly large amount especially when a dog has a breed with an unknown size - influencing gene.

The Catahoula leopard dog is very well known for its Merle gene and pigmentation but seems to always be an ignored breed by dog enthusiasts for some unknown reason

Polygenic traits are controlled by unknown numbers of genes.

Polygenic traits are controlled by an unknown number of genes.

Following a literature search for diseases in other species with clinical and pathological similarities to CDRM, a working hypothesis was established: CDRM is caused by a CAG trinucleotide repeat expansion in an unknown gene.

Therefore, it is inappropriate to assume an additive genetic risk model of three susceptibility genes by using a genetic risk score if the cG × cG is unknown.