Not exact matches
Therefore, those were chosen to test whether the molecules produced
by the neural stem cells of patients alter the
angiogenic capacity of the cells.
Vice versa, pericyte recruitment
by nascent vessels occurs during the later steps of the
angiogenic cascade providing stabilization and maturation signals2.
In turn, tumour angiogenesis is characterized
by a pathological patency of the
angiogenic stimulus resulting in a chaotropic, pro-
angiogenic and permanently immature vasculature.
A major aspect of this process is the production of multiple
angiogenic cytokines and growth factors in response to hypoxia / ischemia, which is mediated
by the transcription factor HIF - 1 (hypoxia - inducible factor 1).
Previous efforts to treat ischemia
by creating new blood vessels have focused on delivering
angiogenic growth factors like vascular endothelial growth factor (VEGF) to ischemic sites.
The
angiogenic response was quantified
by microvessel counting according to published criteria [47].
Secretion of
Angiogenic and Antiapoptotic Factors
by Human Adipose Stromal Cells (March 16, 2004) in Circulation.
More interestingly, the effects on infarction size, survival rates and cardiac function can be observed even if the dietary intervention is induced after the ischemic event,
by increasing the expression of
angiogenic factors and increased vascularization of the damaged myocardium, proposing a novel non-pharmacological therapy for subjects with chronic heart failure (43).
According to experts,
by modulating the secretion of
angiogenic factors in ovarian cancer cells, ginger is can be one of the most potent natural ingredients against this disease.