So a chance encounter in the hotel, which turns into an intimate erotic affair with a self - esteem - challenged woman named Lisa (voiced
by Jennifer Jason Leigh), briefly makes Stone believe he has found a cure to his
anhedonia (without too many spoilers: best.
Our finding that patients with pain reported that they more frequently experienced the depression subscale items reflecting sadness, lack of initiative and
anhedonia than those reflecting low self - worth and lack of meaning is consistent with some earlier research in similar samples of patients with chronic pain.6, 9 It is also interesting to compare these items to those endorsed
by patients with both depression and medical illnesses, who invariably favour a cognitive formulation.29