Genetically modified foods pose a negligible risk of increasing infectious diseases caused
by antibiotic resistant bacteria.
There is an urgent need for new antibiotics capable of treating infections caused
by antibiotic resistant bacteria.»
Not exact matches
The drug targets a wider variety of defence mechanisms used
by antibiotic -
resistant bacteria and can be used in more situations.
One approach used
by Cubist is to target the enzymes produced
by drug -
resistant bacteria that degrade
antibiotic agents and render them useless.
This steady stream of
antibiotics contributes to the development of
antibiotic -
resistant bacteria and superbugs that can not be killed
by standard
antibiotics.
This makes me happy: Research on ribosomes
by Noller and others has led to the development of novel
antibiotics that hold promise for use against drug -
resistant bacteria.
Dangerous
resistant bacteria tend to develop spontaneously in the bodies of patients being given powerful
antibiotics for long periods, and virtually never
by accident in the laboratory or in the field.
This steady stream of
antibiotics contributes to the development of
antibiotic -
resistant bacteria and superbugs that can not be killed
by standard
antibiotics.
Recently, medicine has been confronted
by a surging number of
antibiotic resistant bacteria.
It's all a vicious cycle: use chemicals, create
resistant bacteria, get sick, take
antibiotics, wipe out the good bacteria, get attacked again
by even worse bacteria...
Today's publication of «Tackling Drug
Resistant Infections Globally: Final Report and Recommendations»,
by Lord Jim O'Neill, is a global landmark in the fight to keep
antibiotics effective for both animals and people, says NOAH, which represents the UK animal medicines sector.
By most metrics the
antibiotic -
resistant and susceptible strains of Staphylococcus epidermidis are phenotypically identical, and thus present a major challenge to traditional analytical separation techniques.
The discovery might lead to better ways to fight a class of bacteria that have contributed to a growing public health crisis
by becoming increasingly
resistant to
antibiotic treatments.
Earlier this year the same panel — chaired
by economist Jim O'Neill, formerly of investment bank Goldman Sachs — reported that companies aren't developing new
antibiotics fast enough to keep up with the rate at which bacteria are becoming
resistant to existing ones.
«We also need to develop delivery systems to deploy the treatment in a variety of settings that are currently affected
by antibiotic -
resistant bacteria.»
That's good news because many of the most dangerous pathogens that are
resistant to
antibiotics are gram - negative (SN: 6/10/17, p. 8), according to a list released
by the WHO in February.
A new broad range
antibiotic, developed jointly
by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug -
resistant Staphylococcus (MRSA) bacteria that do not respond to traditional drugs.
Infected Infections Page 20,
by Linda Marsa A new weapon against
antibiotic -
resistant bacteria could be here to stay.
A recent study from a U.K. commission on antimicrobial resistance estimated that
by 2050,
antibiotic -
resistant bacterial infections will kill 10 million people per year, if no new drugs are developed.
For the first time, scientists have shown that MRSA (methicillin -
resistant Staphylococcus aureus) and other
antibiotic -
resistant «superbug» infections can be tracked across Europe
by combining whole - genome sequencing with a web - based system.
The
antibiotic, first identified
by Nosopharm, is unique and promising on two fronts: its unconventional source and its distinct way of killing bacteria, both of which suggest the compound may be effective at treating drug -
resistant or hard - to - treat bacterial infections.
The findings, announced online in the journal Antimicrobial Agents and Chemotherapy and funded
by the National Institutes of Health, provide a needed boost to the field of
antibiotic development, which has been limited in the last four decades and outpaced
by the rise of drug -
resistant bacterial strains.
A study
by scientists at the Center for Infection and Immunity (CII) at Columbia University's Mailman School of Public Health finds New York City house mice carry bacteria responsible for mild to life - threatening gastroenteritis in people, and some of these bacteria may be
resistant to
antibiotics.
The paper,
by three researchers at the University of Vermont, uses a series of time - lapse videos to show that single cells within a community of bacteria randomly use a cascade of proteins to become more or less
antibiotic resistant, even when the community is not threatened
by an
antibiotic.
The work is part of a global response to the need to reduce the use of
antibiotics, driven in part
by President Obama's National Action Plan for Combating
Antibiotic -
Resistant Bacteria.
A 2014 review of antimicrobial resistance reported that unless something is done to stop the evolution of
antibiotic -
resistant bacteria, such so - called superbugs could cost the world $ 100 trillion in gross - domestic - product losses
by 2050.
The top risk for both humans and animals was E.coli and in humans this was followed
by two forms of HIV, Hepatitis C and Staphylococcus aureus, a bacteria which causes food poisoning and is increasingly
resistant to
antibiotics.
The infections have been linked to medical scopes believed to have been contaminated with bacteria that can resist carbapenems, potent
antibiotics that are supposed to be used only in gravely ill patients or those infected
by resistant bacteria.
«They've done this
by altering their genetic make - up; transferring drug -
resistant genes between one another; and creating biofilms, which are multicellular communities where bacteria can be a thousand-fold more
resistant to
antibiotics.»
The illustration, based on electron micrographs and created
by the Centers for Disease Control and Prevention, shows one of these
antibiotic -
resistant bacteria.
In addition to TDA's killing mechanism, the researchers were interested in understanding the mechanism
by which a bacterial strain could become
resistant to the
antibiotic.
The investigators also found that young people with
antibiotic -
resistant infections stayed in the hospital 20 percent longer than those whose infections could be addressed
by antibiotics.
Two days later, the lab results came back, revealing that Gehrke did not have E. coli, but rather a staphylococcus, or staph, infection caused
by methicillin -
resistant Staphylococcus aureus (MRSA), a potent bacterium that has developed resistance to most of the old standby
antibiotics, making it difficult to treat and potentially fatal.
In a new, first - of - its - kind study, researchers from Case Western Reserve University School of Medicine have found a 700 - percent surge in infections caused
by bacteria from the Enterobacteriaceae family
resistant to multiple kinds of
antibiotics among children in the US.
After only a few hours surrounded
by Pseudomonas, Staph became
antibiotic -
resistant.
Cow dung encourages
antibiotic -
resistant bacteria to grow, even if it comes from drug - free cows, according to a study
by Jo Handelsman, associate director for science at the White House Office of Science and Technology Policy.
Biologists traditionally accomplish this feat
by pairing up the desired gene, or transgene, with another gene that makes the cell
resistant to
antibiotics.
A landmark genomic study, with contributors from over two - dozen countries, shows the current problem of
antibiotic resistant typhoid is driven
by a single clade, family of typhoid bacteria, called H58 that has now spread globally.
At the Veterans Affairs Medical Center in Minneapolis, when the
antibiotic gentamicin was no longer given for infections
by a variety of
resistant gut bacteria, including E. coli, the levels of resistance dropped accordingly.
Bacteria can become
resistant to the
antibiotic either as the result of a spontaneous mutation or
by picking up an appropriate «resistance gene» (which codes for a protein that confers resistance) from another bacterium via genetic exchange.
Last month, Lu's lab reported a different approach to combating
resistant bacteria
by identifying combinations of genes that work together to make bacteria more susceptible to
antibiotics.
The breakthrough is another major step forward on the journey to develop a commercially viable drug version based on teixobactin — a natural
antibiotic discovered
by US scientists in soil samples in 2015 which has been heralded as a «gamechanger» in the battle against
antibiotic resistant pathogens such as MRSA and VRE.
To explore the health consequences of bacterial quorum sensing in the crypts, the researchers experimented with an antagonist to turn off quorum sensing in chambers colonized
by methicillin -
resistant S. aureus (MRSA), an
antibiotic -
resistant strain of bacteria that causes human infection.
By some estimates, more than 75 percent of poultry is contaminated with E. coli, much of it
resistant to
antibiotic drugs.
Simple disinfectant use has been shown to reduce rates of infection
by antibiotic -
resistant bacteria, and yet hospitals in many countries, including the United States, often neglect such basic measures.
«It is incredibly tempting to assume that
antibiotics are promoting the spread of resistance
by increasing the rate at which bacteria share
resistant genes with each other, but our research shows they often aren't.»
Our hospitals could one day be brought to their knees
by antibiotic -
resistant superbugs — doctors and scientists are seeing the first glimpse of such a world
The same expert committee, chaired
by economist Jim O'Neill, formerly of investment bank Goldman Sachs, reported earlier this year that companies are not developing new
antibiotics fast enough to keep up with the rate at which bacteria are becoming
resistant to existing ones.
So much so that a 2014 study commissioned
by the Prime Minister of the United Kingdom predicted that, if the problem is left unchecked, in less than 35 years more people will die from
antibiotic resistant superbugs than from cancer.
«We showed at the single - cell level that the exchange of
resistant genes is not influenced
by antibiotics at all, which is in contrast to the literature.»