Sentences with phrase «by autoimmune destruction»

Not exact matches

MSCs have also shown to prevent autoimmune B cell destruction and subsequent diabetes in NOD mice by inducing Tregs 45.

Type I diabetes is characterized by insulin deficiency primarily caused by the autoimmune - mediated destruction of insulin secreting beta cells located in the pancreas.

Genetic mapping of variants conferring a small disease risk can identify pathways in complex disorders, as exemplified by our discovery of inherited, quantitative alterations of CTLA4 contributing to autoimmune tissue destruction.

Another potential mechanism through which iodine exacerbates or induces Hashimoto's is by up - regulating Th17 cells, the immune cell subset responsible for tissue destruction in autoimmune disease, and by suppressing development of regulatory T cells, the population that invokes oral tolerance to arrest autoimmune responses (31).

Rheumatoid arthritis is a chronic, systemic autoimmune disease characterized by persistent pain and stiffness, along with progressive joint destruction, particularly in the hands and feet, leading to crippling deformities.

Some patients with Hashimoto's disease — the autoimmune disease that causes the slow destruction of the thyroid gland by antibodies — also go through temporary periods of hyperthyroidism as their gland slowly becomes less functional.

Hypothyroidism and hyperthyroidism are often caused by autoimmune disorders that attack the body, causing inflammation and destruction of tissue.

Dry eye can be caused by a variety of causes, but the most common cause is an autoimmune destruction of the lacrimal glands around the eye.

Hemolytic anemia: anemia caused by the destruction of the red blood cells by an autoimmune process.

Granulomatous sebaceous adenitis: a disease of sebaceous (sweat) skin glands characterized by reactive tissue growth and autoimmune destruction of the sebaceous glands.

A dog with a normal T4, increased cTSH, and positive TgAA will be considered to have autoimmune thyroid disease which has been compensated for by the production of more T4 in response to destruction of some T4 by the antibodies, and the subsequent release of more cTSH.

This latter group has the latent autoimmune diabetes of adults (LADA) form of type 1 diabetes, which is characterized by gradual β - cell destruction over months or years and is not associated with obesity (75).

SLE is an autoimmune disease characterised by inflammation and destruction of a variety of tissues.

While in many cases we don't know the causes of an underactive thyroid gland and thyroid atrophy in dogs, in other cases there is an autoimmune destruction of the thyroid gland by the dog's own immune system.