Sentences with phrase «by calcitriol»
Not exact matches
Calcitriol production is carried out by the enzyme CYP27B1, but the genomic regions that the team deleted in the experimental mice are far away from the gene encoding this enzyme.
https://www.sciencedaily.com/
In these non-kidney sites, calcitriol seems to serve an altogether different purpose: it appears to play no role in regulation of minerals, and its production is induced by inflammation rather than by the hormones that control calcitriol synthesis in the kidneys.
Calcitriol mediates its biological effects by binding to the vitamin D receptor (VDR), which is principally located in the nuclei of target cells.