One study looked at the effect of virgin coconut oil when supplemented in a diet high in consumption of heated vegetable oils, and how virgin coconut oil protected the liver and kidneys, and the other study looked at how virgin coconut oil can reverse the free radical damage done
by cancer chemotherapy drugs.
Published in the prestigious journal PLOS ONE, the researchers say that combining grape seed extracts with chemotherapy has potential as a new approach for bowel cancer treatment - to both reduce intestinal damage commonly caused
by cancer chemotherapy and to enhance its effect.
In a beautifully ironic twist for a natural chemical falsely accused of causing stomach cancer, capsaicin has been shown to be «absolutely effective» in alleviating the pain from oral stomatitis, mouth sores caused
by cancer chemotherapy and radiation treatments, according to Dr. Ann M. Berger of Yale University's Pain Management Center.
Not exact matches
«My family was shocked
by how many
cancer patients had difficulty getting to their
chemotherapy treatments.»
Chemotherapy works
by killing
cancer cells
by targeting fast - dividing cells, and in most cases, kills off some healthy cells along the way, including nerve cells in the brain.
Those drugs in combination reduce patients «risk of death or their
cancer progressing
by 42 percent versus
chemotherapy, still beating Wall Street «s estimates.
For years it has been used
by cancer patients undergoing
chemotherapy to battle the often debilitating effects of nausea.
The actor was knighted
by the Queen at Windsor Castle in 2015, when he was midway through a course of
chemotherapy for pancreatic
cancer.
Doxorubicin is a
chemotherapy drug used to treat a wide range of
cancers by preventing
cancer cells from replicating.
Researchers led
by Patricia Donahoe and Xiaolong Wei of Massachusetts General Hospital and Harvard Medical School found that the common
chemotherapy agent doxorubicin actually encourages the growth of ovarian
cancer stem cells.
«Cervical
cancer patients are currently treated as a uniform group based on
chemotherapy and radiation regimens that help the largest percentage of people; however, one third of these patients are not helped
by standard therapies,» Banister said.
Chemotherapy drugs designed to kill tumors may actually encourage ovarian
cancer by stimulating the growth of cells that give rise to the malignancy, a new study finds.
Inspired
by his own bout of leukemia to try to find a better
cancer treatment, retired broadcasting station owner Kanzius guessed that as an alternative to
chemotherapy, he could inject tumors with metal ions, then use radio waves to heat the metal and destroy cancerous cells.
So far there's no approved drug on the market that reverses
cancer chemotherapy resistance caused
by P - glycoprotein, or P - gp for short, said Vogel, a biochemistry professor at SMU.
McKenna and his team have identified four different drugs — including the anti-HIV drug nelfinavir — that can disrupt the process
by which hypoxia occurs, restoring proper blood flow to the tumours and making them more vulnerable to
chemotherapy (
Cancer Research, DOI: 10.1158 / 0008 - 5472.
By creating an experimental model of leukemia in mice whose
cancer cells were resistant to
chemotherapy the team was able to caracterize these cells» metabolic profile and observed certain modifications at the level of the mitochondria.
«They also suggest that low - dose metronomic
chemotherapy or targeting the chemokine signaling mediated
by chemo - treated fibroblasts may improve the therapeutic outcome in desmoplastic
cancers.»
By hitting breast
cancer cells with a targeted therapeutic immediately after
chemotherapy, researchers from Brigham and Women's Hospital (BWH) were able to target
cancer cells during a transitional stage when they were most vulnerable, killing cells and shrinking tumors in the lab and in pre-clinical models.
By hitting breast
cancer cells with a targeted therapeutic immediately after
chemotherapy, researchers were able to target
cancer cells during a transitional stage when they were most vulnerable.
By the time of diagnosis the majority of women with ovarian cancer already have extensive spread of the disease which makes it difficult to treat by surgery or chemotherap
By the time of diagnosis the majority of women with ovarian
cancer already have extensive spread of the disease which makes it difficult to treat
by surgery or chemotherap
by surgery or
chemotherapy.
«In pancreatic, ovarian and liver
cancers, we hope that
by adding anti-cancer stem cell drugs to standard of care, we can control proliferating cells within the tumor that could otherwise help the tumor regenerate in the face of existing
chemotherapies.»
A blood
cancer characterized
by the rapid growth of abnormal white blood cells, AML is typically treated with
chemotherapy, in some cases followed
by a stem cell transplant.
Of the dogs stricken with osteosarcoma, 35 had the
cancer in a leg which was subsequently amputated, followed
by chemotherapy, which is the standard - of - care treatment; the dogs with elevated total cholesterol had a median survival time of 455 days, more than 200 days greater than the median survival time for dogs with normal cholesterol.
We identified patients with mutations that predict phenomenal outcomes in the disease; this is a group of women with endometrial
cancer who won't need the financial, physical or emotional toll of
chemotherapy at all — they're patients who are probably cured
by surgery alone.
The addition of high doses of a form of vitamin A could help make
chemotherapy more successful in treating pancreatic
cancer, according to an early study
by Queen Mary University of London (QMUL).
By using «gemcitabine»
chemotherapy to target
cancer cells, and a form of vitamin A to target the surrounding stromal cells, the combined approach led to a reduction in
cancer cell proliferation and invasion.
«Pancreatic
cancer is extremely hard to treat
by chemotherapy, so this finding is important because vitamin A targets the non-cancerous tissue and makes the existing
chemotherapy more effective, killing the
cancer cells and shrinking tumours.
Most
cancer chemotherapy relies on cells absorbing drugs
by diffusion across the cell membrane.
«CRKII most likely regulates the stability of mutated epidermal growth factor receptors and drives
cancer growth
by promoting signaling, or communication, within
cancer cells,» said Julia Petschnigg, lead author on the paper and a postdoctoral fellow at U of T. «We found that a combinatorial
chemotherapy that inhibits those mutated receptors and CRKII could be beneficial in treating lung
cancer.»
Cancer cells had essentially figured out how to survive
by rewiring their metabolism in response to
chemotherapy.
Potential
cancer treatments are loitering in the wings as clinical trials are delayed
by widespread shortages of common
chemotherapy drugs.
To date, it was assumed that chloroquine increases the sensitivity of
cancer cells to
chemotherapy by means of a direct effect on the
cancer cells.
But a new study reports that these tiny flecks of carbon can shrink tumors in mice
by delivering
chemotherapy drugs to
cancer cells.
This is characterised
by the targeted strengthening of the body's own immune cells, unlike in
chemotherapy, in which the aim is direct destruction of the
cancer cells.
Autophagy has emerged as a key pathway that
cancer cells use to survive in the face of assault
by chemotherapy and radiation; however, autophagy as a potential druggable mechanism in patients who become resistant to BRAF inhibitors has not been investigated.
«We hope that our test will significantly improve the odds of survival of breast
cancer patients
by allowing doctors to identify the most effective but least toxic form of
chemotherapy for each individual patient before the treatment begins.»
Rad3 signalling ensures that cells do not divide before DNA damages are repaired and thus provides
cancer cells with a mechanism to resist
chemotherapy by repairing these DNA damages.
As part of the project, announced last week
by Kenneth Hagemann, director of the Pentagon's Defense Nuclear Agency, 24 soldiers from Brooks Air Force Base in Texas are taking prescription drugs — ondansetron hydrochloride and granisetron hydrochloride — that are given to
cancer patients undergoing radiotherapy or
chemotherapy.
A drug used to treat men with late - stage prostate
cancer proved effective in stemming progression of the disease in research participants who had not yet received chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute at Oregon Health & Science University (
cancer proved effective in stemming progression of the disease in research participants who had not yet received
chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led
by the Knight
Cancer Institute at Oregon Health & Science University (
Cancer Institute at Oregon Health & Science University (OHSU).
This analysis, done on separate samples from the same patient, revealed that many of the affected genes confer advantages to
cancer cells
by, for example, enhancing cell migration or resistance to
chemotherapy.
«Triple - negative breast
cancers are
cancer cells that lack three receptors targeted
by current
chemotherapy regimens.
For example, women whose
cancer was no longer controlled
by letrozole or other aromatase inhibitors, those who had already begun to receive
chemotherapy, and premenopausal patients with metastatic disease.
A new therapeutic approach tested
by a team from Maisonneuve - Rosemont Hospital (CIUSSS - EST, Montreal) and the University of Montreal gives promising results for the treatment of multiple myeloma, a
cancer of the bone marrow currently considered incurable with conventional
chemotherapy and for which the average life expectancy is about 6 or 7 years.
A phase I clinical trial conducted
by investigators at the University of Texas San Antonio, showed that the combination of HCQ and the
chemotherapy drug vorinostat in 27 patients with advanced solid tumors, including renal cell carcinoma and colon
cancer, was clinically safe and inhibited autophagy.
A drug recently developed
by Pfizer, crizotinib, targets ALK and is currently given to patients with ALK positive lung
cancer when their
cancer has worsened after initial
chemotherapy.
The study, which will be published December 21 in the Journal of Cell Biology, suggests that the loss of these particular Numb proteins makes breast
cancers more aggressive and resistant to
chemotherapy, but points the way toward new therapeutic approaches that could improve patient outcome
by preserving p53 levels.
The researchers then exposed cells from each of these lines to a panel of 31 different drug treatments — including 23
chemotherapy compounds approved
by the FDA for breast and ovarian
cancers, six targeted
cancer drugs, and two common drug combinations.
Rather,
cancer patients — whose eggs might be destroyed
by chemotherapy or radiotherapy — will benefit the most if this still - experimental procedure becomes practical.
«Since 95 percent of
cancer patients still get chemo, we realized we could make a major impact on
cancer treatment
by helping clinicians prescribe the right
chemotherapy drug,» said Sourav Bandyopadhyay, PhD, a professor of bioengineering and therapeutic sciences in UCSF's Schools of Pharmacy and Medicine and senior author on the new study.
In mice with pancreatic
cancer, three days of fasudil treatment prior to standard
chemotherapy increased survival time
by 47 per cent.