Sentences with phrase «by cancer therapy»

Other major projects include systematic identification of biomarkers to improve clinical management of cardiotoxicity induced by cancer therapies, identification of ectopic pregnancy biomarkers, and use of chemical crosslinking coupled with high resolution mass spectrometry and molecular modeling to determine structures and dynamics of large protein complexes.

Not exact matches

There are more than 80 immune - related cancer therapies currently in clinical trials, fueled by many billions of dollars in pharmaceutical investment from the likes of Bristol - Myers Squibb bmy, Merck mrk, Pfizer pfe, and dozens of biotechs.
Of 12 major, large - cap biopharmaceutical companies examined by Deloitte, the industry appears to be homing in on cancer therapies — and for a good economic reason.
And there have been developments in cellular therapies to treat cancer, with two treatments aiming for approval by the end of 2017.
Publishing a commentary about Bitcoin by an institutional economics professor is as responsible as letting a village witch doctor give lectures on the merits of proton radiation therapy to treat cancer («The Bitcoin myth,» March 3).
Therapy Services at Alden Long Grove includes the specialized treatment of injuries and disorders — particularly those sustained by trauma, orthopedic or neurological injury, burns, cancer or wounds.
Adding abiraterone to hormone therapy at the start of treatment for prostate cancer improves survival by 37 per cent, according to the results of one of the largest ever clinical trials for prostate cancer presented at the 2017 ASCO Annual Meeting in Chicago and published in the New England Journal of Medicine.
During this in depth study, an international team of researchers led by British scientists investigated the impact of anti-hormone therapy on samples taken from patients with prostate cancer.
«Used in cancer therapy, this process could increase the impact of a treatment by heating the cancer cells while introducing the drug compound into the tumor.»
The researchers confirmed some of these findings by analyzing how effective radiation therapy was in 29 colon cancer tumors that metastasized to either the liver or lung.
«If we know which genes are damaged in a breast cancer patient's immune system, prevention or even therapy can be tailored by giving vaccines or perhaps antiviral drugs to reduce the chances of recurrence,» said Friedenson.
CAR - T cell therapy took the cancer world by storm in the summer of 2010.
A route used by tumor cells to spread could be exploited to make stem cells for regenerative medicine and cancer therapies
«Cervical cancer patients are currently treated as a uniform group based on chemotherapy and radiation regimens that help the largest percentage of people; however, one third of these patients are not helped by standard therapies,» Banister said.
Moffitt Cancer Center researchers have contributed to these advances by developing the first test that analyzes the sensitivity of tumors to radiation therapy.
The failure of a pancreatic cancer therapy, announced Wednesday by its maker Amgen, is yet another sign that a once - promising class of cancer treatments has failed to meet expectations.
Led by researchers at the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), the retrospective study suggested that a pattern of molecules called microRNA (miRNA) in tumor cells might predict patients» response to radiation therapy.
But success could leave a lasting mark on cancer care, by helping hundreds of thousands of patients every year, far more than other genetically targeted therapies.
By combining this strategy with cancer cell - targeting materials, we should be able to develop a therapy for glioblastoma and other challenging cancers in the future.»
«Given the devastating impact of cancer metastasis and the dire need for therapies to combat tumor spread, we're highly encouraged by these findings and excited about the therapeutic possibilities they open up.»
Most cancer therapies are aimed at halting cancer growth by stopping cells from rapidly dividing.
In science news around the world, NASA's Cassini mission is about to take its final plunge into the atmosphere of Saturn after 13 years providing an unprecedented view of the planet and its moons, a fight over whether to preserve or develop of one Europe's oldest gold mining sites heats up again, the U.S. Food and Drug Administration approves the first cancer gene therapy for people, a U.S. court gives a green light to a $ 1 billion lawsuit brought by the Guatemalan victims and survivors of mid — 20th century syphilis experiments by research institutions including Johns Hopkins University, and more.
Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).
In managing diseases like cancer, for instance, he often subscribes to traditional modalities offset by therapies that reduce a drug's toxicity (and may also increase its effectiveness).
CANCER CRUSH In CAR - T cell therapy, a cancer treatment approved by the FDA this year for certain blood cancers, a patient's T cells (teal) are genetically modified to hunt down and kill cancer cells (blue).
The researchers believe there are other disease entities, aside from cancers, that may be significantly affected by targeted epigenetic therapies.
«This could be useful in developing new combination therapies, where multiple drugs are used simultaneously to treat a cancer by attacking different parts of the cancer cells at the same time.»
The study, «AKR1B1 promotes basal - like breast cancer progression by a positive feedback loop that activates the EMT program,» which has been published in The Journal of Experimental Medicine, suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer.
The experimental therapy, which involves administering a drug currently used in cancer therapy trials, treats cocaine addiction by inhibiting memories responsible for cravings.
Provenge, made by the biotech company Dendreon, is one of a wave of extraordinarily expensive new cancer therapies that, in clinical trials, extended survival only modestly.
My cancer systems biology team at the University of California, Merced, is tackling diagnosis and treatment of therapy - resistant cancers by elucidating the network of changes within cells as a way to identify new drug targets and circumvent cancer resistance.
Stamets furnished capsules of freeze - dried fungus for a seven - year, NIH - funded study by Bastyr University and the University of Minnesota to determine whether turkey tail mushrooms could help breast cancer patients whose immune systems had been compromised by radiation therapy.
Treatment for advanced melanoma has seen success with targeted therapies — drugs that interfere with division and growth of cancer cells by targeting key molecules — especially when multiple drugs are used in combination.
Epigenetic therapies are thought to work in two ways to fix these errors in cancer cells — by correcting the «position» of the gene switches and by making the cell appear as though it's infected by a virus, triggering the immune system.
The finding, reported by a Stand Up to Cancer - Prostate Cancer Foundation Dream Team in the May 21 edition of the journal Cell, is based on an analysis of tumor samples from 150 men with metastatic prostate cancer that no longer responded to standard hormone - blocking thCancer - Prostate Cancer Foundation Dream Team in the May 21 edition of the journal Cell, is based on an analysis of tumor samples from 150 men with metastatic prostate cancer that no longer responded to standard hormone - blocking thCancer Foundation Dream Team in the May 21 edition of the journal Cell, is based on an analysis of tumor samples from 150 men with metastatic prostate cancer that no longer responded to standard hormone - blocking thcancer that no longer responded to standard hormone - blocking therapy.
The gold - iron oxide core - shell nanorods may be useful in cancer therapy, with MRI imaging enabled by the iron oxide shell, and local heating created by the photothermal effect on the gold nanorod core killing cancer cells.
The study by the University of Southern California «exemplifies a real opportunity for the oncology community, one that embraces an integrated approach to understanding cancer progression and developing therapies that exploit evolution rather than ignore it,» said Anderson.
«LFEX laser» enables us to generate high energy pulses of quantum beams with large current, and one can expect such medical applications as particle beam cancer therapy and non-destructive inspection for bridges and etc. (or defect inspection by gamma - ray beam and neutrons).
Dr. De Carvalho says: «Another important implication of our finding is that since decitabine induces an anti-viral response, which is highly immunogenic, it may be useful to combine this agent with immune therapy to further advance personalized cancer medicine by boosting an individual's natural defenses to fight disease.
«Droplet explosion by shock waves, relevant to nuclear medicine: Ion beam cancer therapy could be improved if ion - induced shock waves are discovered.»
During the 1990s, the incidence of breast cancer climbed by about 15 percent, in synchrony with a growing number of women receiving hormone replacement therapy.
«This finding could be relevant to the many thousands of individuals affected by these cancers and could prevent unnecessary therapy,» said Dr. Shay, Associate Director for Education and Training for the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern.
This is why findings by Cincinnati Cancer Center researchers, showing that a tumor suppressive microRNA, when activated by an anti-estrogen drug, could contribute to development of future targeted therapies, are important.
ADT, which suppresses the production of testosterone by either medical or surgical castration, remains the gold standard for treating advanced prostate cancer, either alone or with radiation therapy.
Denmeade says the combination of drugs that block testosterone production and receptors, called androgen deprivation therapy, may make prostate cancer more aggressive over time by enabling prostate cancer cells to subvert attempts to block testosterone receptors.
«By understanding how stress accelerates invasion in aggressive breast tumor cells, this work will inform future studies into whether beta - blockers could be a useful adjuvant therapy in the treatment of some aggressive breast cancers
Previous studies, he adds, have shown that taking testosterone at the wrong time — particularly by men with symptoms of active cancer progression who have not yet received testosterone - blocking therapy — can make the disease worse.
«Disrupting this circuit by targeting any of its individual components blocks the expression of these transcription factors and significantly impairs therapy - resistant prostate cancer,» said TSRI Research Associate Ji - Hak Jeong, the first author of the study.
A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer.
The proposed clinical trial, in which researchers would use CRISPR to engineer immune cells to fight cancer, won approval from the Recombinant DNA Advisory Committee (RAC) at the U.S. National Institutes of Health, a panel that has traditionally vetted the safety and ethics of gene therapy trials funded by the U.S. government and others.
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