Sentences with phrase «by cell degeneration»

Recent studies suggest that the total loss in brain volume due to atrophy — a wasting away of tissue caused by cell degeneration — between our teen years and old age is 15 percent or more, which means that by the time we're in our seventies, our brains have shrunk to the size they were when we were between 2 and 3 years old.

Not exact matches

PRA is caused by the degeneration of the photoreceptor cells, rods and cones, which are needed for dark and day light vision, respectively.

«By putting in healthy cells, we can basically stop and prevent the degeneration of the photoreceptors,» says Sally Temple, the co-founder and scientific director of the Neural Stem Cell Institute in Rensselaer, N.Y.

«Retinal implant designed to replace support cells damaged by dry age - related macular degeneration.»

Experiments conducted in mice and in human ALS cells reveal that when RIPK1 is out of control, it can spark axonal damage by setting off a chemical chain reaction that culminates in stripping the protective myelin off of axons and triggering axonal degeneration — the hallmark of ALS.

By activating the Ret receptor, the scientists were able to prevent in flies and human cell cultures the degeneration of mitochondria, which is caused by a gene defect related to Parkinson's diseasBy activating the Ret receptor, the scientists were able to prevent in flies and human cell cultures the degeneration of mitochondria, which is caused by a gene defect related to Parkinson's diseasby a gene defect related to Parkinson's disease.

«The growth factor released by these genetically engineered cells will bath the other cells in the growth factor, slow down the degeneration and thereby improve, or slow the decline in Alzheimer's disease,» Tuszynski explains.

«Our study sounds a serious warning about the possible detrimental side effects of this strategy, since we have shown that such antibodies cause dramatic degeneration of nerve cells by interfering with the normal on - off function of the prion protein,» he added.

One theory has been that calorie restriction slows age - related degeneration and enables more efficient tissue function by influencing the integrity and activity of adult stem cells, the precursor cells that dwell within specific tissues and give rise to the diversity of cell types that compose that tissue.

Many diseases that lead to blindness, such as glaucoma and macular degeneration, are caused by the death of certain cells in the human retina that lack the ability to regenerate.

It has been designed for treating the «dry» form of macular degeneration, caused by deposits on the retina gradually killing retinal pigment epithelial cells, which support light - capturing cells.

In a second trial starting around the same time, a different team in Zhengzhou will use ES cells to target vision loss caused by age - related macular degeneration.

But some signal provided by muscular injury or degeneration prompts satellite cells to start dividing and then to integrate themselves into damaged fibers, repairing the muscle tissue.

Commonly known as Lou Gehrig's disease (after the famed New York Yankee slugger who succumbed to it in 1941 at age 37), ALS is a poorly understood, incurable disorder characterized by the degeneration of motor neurons (nerve cells that control voluntary motion).

As reported in the new study, the researchers were able to postpone the onset of hearing loss and associated hair cell degeneration by about a month, providing enough time to inject normal copies of the Clarin - 1 gene into the ear before the onset of hearing loss to see if the treatment was effective.

The new study by researchers at The Neuro shifts the focus to the loss or degeneration of axons, the nerve - cell «branches» that receive and distribute neurochemical signals among neurons.

Johns Hopkins University biologists have found that a protein that plays a key role in the lives of stem cells can bolster the growth of damaged muscle tissue, a step that could potentially contribute to treatments for muscle degeneration caused by old age and diseases such as muscular dystrophy.

Featured on the cover of Developmental Cell, a paper by OIST researchers revealed the mechanistic link between photoreceptor cell degeneration and defects in protein transpCell, a paper by OIST researchers revealed the mechanistic link between photoreceptor cell degeneration and defects in protein transpcell degeneration and defects in protein transport.

«Many retinal diseases are manifested by the degeneration of photoreceptor cells.»

Her research showed that degeneration is caused by perturbations in the epidermis due to an increase in matrix - metalloproteinase 13 (MMP - 13), an enzyme that degrades the collagen, or «glue,» between the cells.

It is characterized by the wasting of skeletal muscles and caused by progressive degeneration of nerve cells in the spinal cord; the disease leads to increasing muscular weakness, atrophy and premature death due to respiratory problems.

This research points to exciting new possibilities for preventing or reversing the disabling vision loss caused by age - related macular degeneration, diabetic retinopathy, retinitis pigmentosa, glaucoma, and other diseases that damage the retina, the layer of light - sensitive nerve cells that line the back of the eye.

A team led by Steven Schwartz at UCLA administered about 50,000 cells Tuesday into one eye of a volunteer suffering from Stargardt Macular Dystrophy, a progressive form of blindness that usually begins in childhood, and another with Dry Age - Related Macular Degeneration, the leading cause of blindness in the developed world, Advanced Cell Technology, which is sponsoring the study, announced Thursday.

The elderly woman, who had macular degeneration, thought she was paying to participate in a clinical trial that would save her sight by injecting stem cells into both eyes.

«By comparing these diseased neurons with the «genetically corrected» healthy neurons, we could see — cell by cell — how the Tau mutation leads to the abnormal build up of Tau and, over time, neuronal degeneration and death.&raquBy comparing these diseased neurons with the «genetically corrected» healthy neurons, we could see — cell by cell — how the Tau mutation leads to the abnormal build up of Tau and, over time, neuronal degeneration and death.&raquby cell — how the Tau mutation leads to the abnormal build up of Tau and, over time, neuronal degeneration and death.»

These findings suggest that RPE cells, derived from iPS cells, could be used to treat blindness in humans, such as blindness caused by age - related macular degeneration, a leading cause of blindness in the Western world.

SMA is a genetic, neuromuscular disease caused by progressive degeneration of nerve cells in the spinal cord that leads to muscular weakness and atrophy and increased risk for early death due to respiratory failure.

They were financed by Advanced Cell Technology, a biotech company with laboratories in Marlborough, Massachusetts, that recently won approval from the U.S. Food and Drug Administration to test the treatment in 24 patients suffering from either dry advanced macular degeneration, or a juvenile form of the disease known as Stargardt's.

Spinal muscular atrophy involves wasting of the skeletal muscles and is caused by gradual degeneration of nerve cells in the spinal cord.

Leber Hereditary Optic Neuropathy (LHON) is a rare maternally inherited mitochondrial genetic disease, characterized by the degeneration of retinal ganglion cells that results in brutal and irreversible vision loss that can lead to legal blindness, and mainly affects adolescents and young adults.

Caused by progressive degeneration of nerve cells in the spinal cord, the disease leads to increasing muscular weakness and atrophy.

And the ability to regenerate new, unspecialized cells could revolutionize treatment for conditions caused by cellular degeneration.

Corticobasal degeneration is a progressive neurological disorder characterized by nerve cell loss and atrophy (shrinkage) of various regions of the brain, including the cerebral cortex and the basal ganglia (which helps to start and control movements, as well as other functions).

Fueled by a recent resurgence in public financing and compelling clinical data for indications as diverse as acute macular degeneration and pancreatic cancer, a growing number of cell therapies are driving toward pivotal clinical studies and commercialization.

Feel Young and Beautiful Again Mango Butter is known for its anti-aging and skin protecting qualities by reducing degeneration of skin cells and restoring elasticity.

«While this is happening [degeneration of the thymus gland], the B cells, which normally are under the control of the thymus cells, are not killed by estrogen, and actually seem to be stimulated by estrogen to produce certain types of antibodies, but they are more likely to produce autoimmune antibodies.»

Because Age Related Macular Degeneration comes from the breaking down of retinal cells, the vitamins and nutrients which have been found to protect eyes from AMD are aiding the body by keeping the eyes healthy and improving eyesight.

Alzheimer's is not caused by damaged blood vessels, but by degeneration of brain cells's proteins.

Antioxidants neutralize that damage by offering up one of their own electrons, thereby helping to prevent cell and tissue breakdown that can result in further damage and disease — everything from wrinkles and hyperpigmentation to chronic conditions including cancer, cardiovascular disease, Alzheimer's, Parkinson's, and eye diseases such as cataracts and age - related macular degeneration.

By doing this, vitamin E slows mental and physical degeneration of cells that causes aging.

In the study, tests on human cells demonstrated that catuaba may help fight Parkinson's disease by protecting against the degeneration of certain nerve cells.

Aging, tissue degeneration, and skin changes may be brought about by the damage that free radicals cause to cells unprotected by antioxidant nutrients in the body.

All forms of CRD are characterized by the initial loss of cones, the cells in the retina that are responsible for vision in bright light / daylight, followed by the degeneration of rods, the retinal cells that operate during night vision.

The disease itself is painless but affected dogs should be regularly monitored by an ophthalmologist to treat possible secondary effects of PRA (the most widespread form of PRA across dog breeds) IG - PRA1 first presents as a loss of vision in dim light conditions due to degeneration of rod cells in the retina.

ERG abnormalities are evident by 5 — 6 weeks of age and cell degeneration is present by 4 months, suggesting the mutant protein has a toxic gain of function that severely compromises the early stage of development of the photoreceptors.

Liver failure due to cancer, toxins or cirrhosisa chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue.

Rod Cone Dysplasia Type 1b (rcd1b), previously named CRD1, is an early - onset form of retinal degeneration that is characterized by the loss of rods and cones, the cells in the retina that are responsible for vision.

A different form of congenital hereditary deafness is seen in the Doberman, which is also accompanied by vestibular (balance) disturbance; this deafness results from a different mechanism where hair cell death is not the result of degeneration of the stria but is instead the primary pathology.

Diabetes is caused by degeneration of insulin - producing cells in the pancreas (in the Islets of Langerhaans to be precise).

A progressive degeneration is caused by fibrosis, or thickening, of the muscle cells which lead to loss of muscle function.