Sentences with phrase «by changes at the federal level»

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These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

A 0.5 % small business tax reduction is welcome, but overshadowed by tax increases at the personal level, corporate level, an increase in B.C.'s no - longer - revenue - neutral carbon tax, and the corresponding pending changes by the federal government as to how small business owners can manage their affairs.

From 1990 to 2005, he was Director Fiscal Policy Division Department of Finance, responsible for overall preparation of the federal budget; preparation and assessment of medium - and long - term projections of federal revenues and expenses and implications for fiscal policy; analysis of fiscal conditions at both the federal and provincial levels; evaluation of various budget proposals; preparation of monthly Fiscal Monitor; with the Office of the Comptroller General (OCG), assessing and evaluating accounting standards proposed by the Public Sector Accounting Board (PSAB) of the CICA and recommending changes in government accounting policies; with the OCG, responsible for implementation of accrual accounting for the federal budget and the government's financial statements.

It seems to me that the most promising mechanisms for real change are at the federal level, by influencing Congress at it considers the reauthorization of the Child Nutrition Act, and at the most local of levels — the individual school — where parents and sympathetic principals can work together to, for example, eliminate treats in the classroom or the sale of objectionable a la carte foods.

-LSB-...] mechanisms for real change are at the federal level, by influencing Congress at it considers the reauthorization of the Child Nutrition Act, and at the most local of levels — the individual school — where parents and -LSB-...]

One year after entering office with a mandate for change, Mayor Shayne Gallo has pushed ahead with an agenda centered on revitalizing the city by battling blight, forming partnerships with state, federal and county government and ending what he calls a «culture of entitlement» at the highest levels of municipal government.

ALBANY, NY (12/28/2011)(readMedia)-- A coalition of CSEA, PEF, UUP, NYSCOPBA, NYSTPBA, NYSPIA, and AFSCME Council 82, unions representing virtually all of New York State employees have filed lawsuits in federal court challenging the Cuomo Administration's unilateral increase in the percentage of health insurance contributions required of state retirees.The legal challenge applies to changes made by the administration this fall and covers state employees who have retired and seen their share of health insurance premium increase beyond the level at which they retired.

Underlining a point made by Deputy Secretary Miller, Rodríguez reminded the conference that, to be effective, change must come not only from the federal government but from «high levels of energy at the state and local level.»

Indeed, other changes have involved shifts in power at the local level or even decentralization below the school district level, rather than greater control by the state (or the federal government).

Those who follow federal education policy or work on education at the state level are well aware of a few big changes wrought by the Trump team (with some help from Congress) in its first hundred days, including wiping out the late Obama ESSA accountability regs and easing off on bathroom access rules.

«The next step is to think beyond one company to how we can implement these lessons on a larger scale, perhaps in schools or with community organizations, and ideally by changing the aid application process at the federal level.»

We catalyze action by working with leaders at the federal and state level to effect change.

It lays out approaches to maximize the opportunities presented by recent changes at the state and federal level, including CALPADS new attendance data collection for 2016 - 17 school year, and new chronic absence reporting requirements in the Every Student Succeeds Act.

I. Lead by example through strong action at home and abroad: Making significant progress in combating climate change through domestic actions within the Department and at the federal, regional, and local level.

The report, Building on the best: Keeping Canada's climate promise, used analysis by Navius Research to examine the best climate change policies and solutions being used in Canada and how they can be applied at the federal level.

A former senior researcher in the department, Doug Lord, said yesterday two papers he co-authored with colleagues and was due to present at conferences were suppressed because they suggested sea - levels on the east coast are rising at only one 10th of the rate estimated by the federal government, based on data from the Intergovernmental Panel on Climate Change.

At the federal level, the Bush administration was criticized by Republican and Democratic lawmakers at several recent hearings on climate changAt the federal level, the Bush administration was criticized by Republican and Democratic lawmakers at several recent hearings on climate changat several recent hearings on climate change.

In this installment, we describe a particularly egregious fault that exists in at least one of the prominent models used by the federal government to determine the SCC: The projections of future sea - level rise (a leading driver of future climate change - related damages) from the model are much higher than even the worst - case mainstream scientific thinking on the matter.

This section of the paper concludes by considering what issues are raised for the operation of a new National Indigenous Representative Body in light of these existing mechanisms, as well as in relation to the post-ATSIC arrangements for delivery of services to Indigenous peoples at the federal level, which have substantially changed the operating landscape for Indigenous Affairs.