Moreover, for the first time, they show that changes in whole - organism phenotypic responses are accompanied
by changes in the expression of genes related to intracellular regulatory processes rather than genes thought to be essential for calcification.
Not exact matches
In our leadership work we show our leaders how to transmit a precise type of leadership impact to meet different business outcomes
by using various specific postures and facial
expressions that prime your behaviors to achieve the particular business outcome, as well as signal to others how your behaviors will
change outcomes.
So the Supreme Court, when it practices judicial activism, undercuts democratic participation not only
by substituting its own assertoric judgment for democratic deliberation, or
by ignoring the plain letter of the constitution
in favor of its own political inclinations, but also
by understanding itself as a council of philosopher kings (versus really good lawyers) prudentially adjusting the fundamental nature of American democracy to fit the ever
changing historical horizon that provides the context for its
expression.
But again, and even with the possible implication of divine judgment
in the death of Rachel, we see the repeated motif of the Jacob cycle: the tension between sin and divine grace, the
expression of faith that Jacob - Israel is saved and redeemed only
by the will and purpose of God (35:5), and finally the repetition of the promise and the blessing, and the second account of the
changing of Jacob's name to Israel.
The conference was spearheaded
by Michael Davidson, a man of God who came out of the homosexual life many years ago and heads up a group called Core Issues Trust («a non-profit Christian ministry supporting men and women with homosexual issues who voluntarily seek
change in sexual preference and
expression») and
by Andrea Williams, dynamic barrister and CEO of Christian Concern (an organization that seeks to be «a strong Christian voice
in the public sphere») and the Christian Legal Centre (a legal defense team for British Christians persecuted for their faith).
Then there is wisdom, human wisdom, man's intelligent ordering of his life, the serious employment of right reason, the attempt to find the proper way of life, the whole enterprise that takes form
in political action and personal morality,
in social work and poetry,
in economic management and the building of temples,
in the constant improvement of justice
by changing laws,
in philosophy and technology, the manifold wisdom of man which is also inscribed
in the wisdom of God and which may be an
expression of this wisdom, the first of all God's works that rejoiced before him when he laid the foundations of the world (Proverbs 8:22 ff.).
When
in 169 one of the contestants, Menelaus, was returned to the office, Antiochus, who had already incurred the bitter resentment of faithful Jews
by his interference, sought to correct his financial plight
by entering the Temple himself and stripping it of its considerable movable wealth.31 Antiochus became at once the object of Judaism's bitterest hate; and no doubt
in part
in retaliation but also as an
expression of this ardent Hellenist's frustration with a people slow to
change, he effected an otherwise quite unprovoked attack on Jerusalem
in 168.
While process theism welcomes
expressions of God's dynamic activity, I for one am hesitant ever to endorse any
change in God's values not dictated
by a
change in the objective situation.
But,
in the courts and other public forums, the ACLU now has impressive competition, while the political sea
change of November 1994 has created a circumstance much more sympathetic to the public
expression of arguments informed
by religious tradition.
This general view finds its fullest and clearest New Testament
expression in the Fourth Gospel, was elaborated
in the great creedal discussions of several centuries later, and was finally and definitively formulated
by the Council of Chalcedon
in 451: «One and the same Christ, Son, Lord, only begotten, acknowledged
in two natures, without confusion, without
change, without division, without separation; the distinction of the natures being
by no means taken away because of the union, but rather the property of each nature being preserved and concurring
in one person.
I agree that ozil is probably one of the best crossers
in europe but that being said he is also one of the best passers
in europe, the best way to accomodate this is the way we did last season, make all the playmakers play with fluidity, ramsey / ozil / ox exc should be switching positions all game, to confuse the opposition, which we did so well
in the first half of the season, if we can sustain that type of play whilst
changing formations at the right time, there's no reason why we shouldn't have the title wrapped up
by the time we get to Old Toilet, to see my good old mate Judas's facial
expression when he has to congratulate our achievement
By design unique combinations of the massage mode (designed to signal the body to have a let down by replicating a baby's quick, light sucking) and the expression mode (which replicates the longer stronger deeper sucking a baby changes to once there has been a letdown) as well as setting the vacuum / speed for each you can ensure you get the most milk out in the shortest amount of time for you.&raqu
By design unique combinations of the massage mode (designed to signal the body to have a let down
by replicating a baby's quick, light sucking) and the expression mode (which replicates the longer stronger deeper sucking a baby changes to once there has been a letdown) as well as setting the vacuum / speed for each you can ensure you get the most milk out in the shortest amount of time for you.&raqu
by replicating a baby's quick, light sucking) and the
expression mode (which replicates the longer stronger deeper sucking a baby
changes to once there has been a letdown) as well as setting the vacuum / speed for each you can ensure you get the most milk out
in the shortest amount of time for you.»
In addition to giving your partner a break, it's a chance for you and your baby to start practicing conversation skills
by making eye contact, cooing noises and engaging your baby with
changing facial
expressions.
The Hoylman - Glick measure ---- which is broader than its title suggests, also barring efforts to
change a minor's gender identity and
expression ---- is similar to legislation enacted
in the past two years
by California and New Jersey.
BBC News reported that, while the Registration of Political Parties (Prohibited Words and
Expressions)(Amendment) Order 2005 stipulates that no political party can be registered
in the UK under the name «None of the Above», there is no legislation against a person
changing their name
by deed poll and appearing on the ballot paper as «None Of the Above».
Scientists at Southern Methodist University, led
by Professor and Chair of Biological Sciences Santosh D'Mello, have used RNA - Seq to conduct transcriptome profiling of gene
expression changes in dying neurons.
In the new research, the UB scientists found they could reverse those social deficits with a very low dose of romidepsin, which, they found, restores gene
expression and function using an epigenetic mechanism, where gene
changes are caused
by influences other than DNA sequences.
The overlap
in gene
expression changes when neural progenitor cells are infected
by African or Asian strains of Zika virus.
The direct methylation of the DNA
changes the gene
expression permanently if it takes place
in the control regions of genes (so - called CpG islands), that have been made accessible
by the modification of the histones.
In a new study published in Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expressio
In a new study published
in Physiological Genomics, a team of U.S. researchers tracked in detail how this extreme makeover is controlled by changes in gene expressio
in Physiological Genomics, a team of U.S. researchers tracked
in detail how this extreme makeover is controlled by changes in gene expressio
in detail how this extreme makeover is controlled
by changes in gene expressio
in gene
expression.
The Epstein - Barr virus, which infects some 90 % of Americans, may cause
changes in gene
expression that dramatically increase a person's chance of getting lupus and six other autoimmune disorders, a new study
by Harley, now a rheumatologist at the Cincinnati Children's Hospital Medical Center
in Ohio, and colleagues shows.
The researchers found that the blond hair commonly seen
in Northern Europeans is caused
by a single
change in the DNA that regulates the
expression of a gene that encodes a protein called KITLG, also known as stem cell factor.
Each cell type can be distinguished based on its transcription factors, and a cell can
in certain cases be directly converted from one type to another, simply
by changing the
expression of one or more transcription factors.
The Epstein - Barr virus (EBV), which infects some 90 % of Americans, may cause
changes in gene
expression that dramatically increase a person's chance of getting lupus and six other autoimmune disorders, a new study
by Harley and colleagues shows.
As sensitive as alternative splicing reacts to (slightly) elevated temperature, a temperature - induced
change in gene
expression by fever appears to be a logical consequence.
Kingsley's research has shown that these adaptive
changes are often driven
by changes in the regulatory regions that surround and control gene
expression, rather than within the coding regions of the genes themselves.
Using Epiviz and Bioconductor, the research team found consistent regions of DNA methylation
changes in colon cancer samples generated
by the public Cancer Genome Atlas project and similar gene
expression in these regions of DNA methylation
changes in other cancer types.
Further studies discovered that the BRAF protein could turn on many itch genes, and they showed similar
changes of gene
expression in mice with chronic itch induced
by dry skin and
in mice with allergic contact dermatitis, two of the skin conditions that frequently cause people to scratch incessantly.
Tiny
changes in our genomes can enhance oncogene
expression and contribute to tumorigenesis [Also see Report
by Mansour et al..]
Douglas Thomas, associate professor of medicinal chemistry and pharmacognosy at UIC, and co-workers discovered that nitric oxide plays an important role
in epigenetics — heritable alterations
in gene
expression caused
by mechanisms other than
changes in DNA sequence.
Gene moonlighting can occur merely through
changes in expression, which may result from as little as a single mutation; it does not require the meandering process of random alteration and selection implied
by the duplication and neofunctionalization model.
Analysis showed that incremental
changes in the number of repeats caused non-harmful variations
in the
expression of the genes regulated
by Ssn6.
The researchers discovered that the Activin pathway controls the ability of cocaine to induce this
change in the neurons and determined that the Activin receptor may control this response to cocaine
by regulating the
expression of a number of genes.
«What George's team has accomplished is a technological tour de force,» said Wyss Institute Founding Director Don Ingber, M.D., Ph.D. «
By spotting incredibly subtle but incredibly important
changes in gene
expression and precisely defining their position inside the cell, they have helped open the door to a new age of cellular diagnostics.»
«Many thyroid diseases will be impacted
by changing the
expression levels of the thyroid - specific transcription factor, so we want to investigate FOXE1 more carefully
in future work.»
Hutchinson - Gilford progeria is caused
by a spontaneous mutation during conception
in a gene called LMNA, which encodes a protein called prelamin A. Progeria patients experience a buildup of an abnormal version of prelamin A
in their cells that, among other
changes, distorts the nucleus and alters gene
expression.
For example, because one's genes generally aren't subject to
change, any
change in the influence or
expression of one's genes is likely «triggered»
by other biological and / or environmental processes.
Disregarding the problem of disguises, face - recognition programs can be thrown off
by factors such as
changes in hair and facial hair, different
expressions, and aging.
DNA methylation and the
change in chromatin structures caused
by histone modification are both linked to modification of gene
expression.
«Resilient mice overcome this
change by counteradapting their gene
expression [the suite of genes that act on the nucleus accumbens that are either turned on or off] to clamp down the levels of activity
in the ventral tegmental area.»
This single cell transcriptome analysis followed
by computational analyses enabled the team to identify the gene
expression profiles of cells
in the process of
changing from ES cells to 2CLCs.
«The thing that's impressive is that morphological
changes in the neurons that many labs have seen, both
in fragile X patients as well as
in mice that model fragile X, were reversed
by changing the
expression of this PAK gene.
Gene
expression changes gradually at each stage of treatment, as illustrated
by the color
changes in this series of heat maps.
«Our hypothesis was, if a disease is characterized
by certain
changes in gene
expression and if a drug causes the reverse
changes, then that drug could have a therapeutic effect on the disease,» he says.
Now, researchers at the Institute for Comprehensive Medical Science, Fujita Health University, and ATR Computational Neuroscience Laboratories
in Japan have succeeded
in predicting states of mood -
change - like behavior
by studying the gene
expression patterns
in the brain
in a bipolar disorder mouse model.
Most analytical approaches to this problem are rather rudimentary and involve calculating simple correlations among the genes whose
expression changes in response to a perturbation, clustering the genes
by molecular or known functional class, and drawing crude inferences about mechanism on that basis.
In the current study, the researchers used infradian cyclic locomotor activity in the mutant mice as a proxy for mood - associated changes, and examined their molecular basis in the brain by conducting prediction analyses of the gene expression dat
In the current study, the researchers used infradian cyclic locomotor activity
in the mutant mice as a proxy for mood - associated changes, and examined their molecular basis in the brain by conducting prediction analyses of the gene expression dat
in the mutant mice as a proxy for mood - associated
changes, and examined their molecular basis
in the brain by conducting prediction analyses of the gene expression dat
in the brain
by conducting prediction analyses of the gene
expression data.
Epigenetics is the study of
changes in organisms caused
by modifying gene
expression —
by alcohol, for example — rather than alteration of the genetic code itself.
Additionally, the interpretation of levels of
change in gene
expression in isolation, without the additional statistical rigor provided
by the concomitant analysis of ontological interaction networks, may severely limit critical insights into relevant biologic processes.
Evaluating
changes in gene
expression patterns of Kif5b and Psmd6: Are they regulated
by GOLGA3?