Sentences with phrase «by cisplatin»

Sixteen dogs with histologically confirmed appendicular osteosarcoma were treated by amputation followed by cisplatin and doxorubicin chemotherapy.

Not exact matches

Some very significant medical discoveries were made by accident — penicillin, cisplatin (a chemotherapeutic drug), and even Viagra.

Dartmouth researchers previously demonstrated that STK17A is a protein that is induced when DNA is damaged by the chemotherapeutic drug cisplatin.

A team of researchers led by Dr. Jian Zuo screened over 4,000 drugs for their ability to protect cochlear cells from the chemotherapy agent cisplatin.

In the case of cisplatin - induced hearing loss, kenpaullone appears to protect hair cells by preventing CDK2 from stimulating the production of toxic reactive oxygen species from the cells» mitochondria.

By cutting gelsolin down to a specific fragment and putting it into chemo - resistant cancer cells, the international team discovered they could make these cells susceptible to the cancer - killing effects of cisplatin.

The addition of necitumumab to gemcitabine and cisplatin chemotherapy improved overall survival and progression free survival by 21 % and 16 %, respectively, as compared to chemotherapy alone in patients whose tumours expressed the EGFR protein.

The multicentre trial included 153 patients with surgically - treatable malignant pleural mesothelioma, who were first treated with three chemotherapy cycles of cisplatin and pemetrexed, followed by surgical removal of affected lung tissue, with the goal of complete removal of the cancerous areas of lung.

Aerosol administration was performed as follows, the residual cup was filled with 8mls of the cisplatin agent and the nebulisation time was 10 minutes (almost 1 ml / minute) as observed from our previous studies.14 The aerosol was delivered to the mice (one by one) within a nose only cage that has been previously presented.34 In the groups receiving the intratumoral cisplatin an insulin injection was used to deliver the 2mls of cisplatin within the tumor in different depths, however; a quantity of the drug when the injection was made superficially was lost since it was not accumulated.

Zoledronic acid reverses cisplatin resistance in nasopharyngeal carcinoma cells by activating the mitochondrial apoptotic pathway.

Inhibition of ERβ Induces Resistance to Cisplatin by Enhancing Rad51 — Mediated DNA Repair in Human Medulloblastoma Cell Lines.

Firstly, investigating the toxicity of the inhaled cisplatin and secondly by evaluating the gene expression of ABCA10 gene.

Hyperthermic potentiation of cisplatin by magnetic nanoparticle heaters is correlated with an increase in cell membrane fluidity.

Overexpressed circPVT1, a potential new circular RNA biomarker, contributes to doxorubicin and cisplatin resistance of osteosarcoma cells by regulating ABCB1 Zhu Kun - Peng, Ma Xiao - Long, Zhang Chun - Lin International Journal of Biological Sciences 2018; 14:321 - 330

FDA on chemo beads Cisplatin beads have not been approved by the Food and Drug Administration (FDA) for use in cats.

Cisplatin is then slowly released from the beads, which are reabsorbed by the body over 4 - 6 weeks.

Unfortunately, cisplatin can be deadly in cats, but by including a minuscule dose in the beads, veterinarians are now able to eliminate the former side - effects.

Dogs have often been treated with cisplatin by injecting the fluid right into the affected body cavity (intracavitary treatment).