Sentences with phrase «by computational analysis»

That hobby required a lot of scraping of data from websites followed by computational analysis.

The tested values matched those determined by computational analysis using the new formulas, Ren said.

This single cell transcriptome analysis followed by computational analyses enabled the team to identify the gene expression profiles of cells in the process of changing from ES cells to 2CLCs.

Not exact matches

We differentiated between computational approaches (either based on volume data, such as the number of mentions related to a party or candidate or the occurrence of particular hashtags; or endorsement data, such as the number of Twitter followers, Facebook friends or the number of «likes» received on Facebook walls), sentiment analysis approaches, that pay attention to the language and try to attach a qualitative meaning to the comments (posts, tweets) published by social media users employing automated tools for sentiment analysis (i.e., via natural language processing models or the employment of pre-defined ontological dictionaries), and finally what we call supervised and aggregated sentiment analysis (SASA), that is, techniques that exploit the human codification in their process and focus on the estimation of the aggregated distribution of the opinions, rather than on individual classification of each single text (Ceron et al. 2016).

By applying advanced computational linguistics in order to undertake a computerised text analysis of government policy, the project will provide a detailed picture of government policy.

Producing a short list of strong candidates was in itself a feat, accomplished by applying the right filters to analysis of human and chimpanzee genomes, said co-author Gregory Wray, professor of biology and director of the Duke Center for Genomic and Computational Biology.

Work at Janelia will focus on two areas, «the identification of general principles that govern how information is processed by neuronal circuits, [and] the development of imaging technologies and computational methods for image analysis,» as HHMI puts it on their Web site.

In addition, using methods for the analysis of regulatory networks developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growth.

A team of scientists, led by Jill L. Maron, MD, MPH, Associate Professor of Pediatrics at Tufts Medical Center, reports that by combining gene amplification techniques with advanced computational analysis tools they were able to identify and validate salivary biomarkers to predict oral feeding readiness in preterm infants.

Careful attention to phenotyping diseases, facilitated by our knowledge of the human genome and computational analysis, has allowed observant physicians and physician - scientists to identify and categorize diseases in a manner that has informed basic science, given it new contexts, and in many instances provided important new directions for investigation.

By using computational algorithms for network analysis, virtual pathways can be constructed to determine possible metabolic products.

Planetary scientist Will Grundy of Lowell Observatory in Flagstaff, Ariz., and colleagues used images of Charon taken by the New Horizons spacecraft and computational analysis to demonstrate that methane from Pluto is a reasonable culprit for Charon's rust - colored pole.

«We are currently working on parameter sensitivity analysis and Bayesian calibration of this new model and also on a high resolution regional simulation over the U.S. Corn Belt, all of which would not be possible without the precious computational resources provided by Blue Waters.»

The team then performed comprehensive RNA sequencing on the blood samples followed by computational data analyses to determine what genes and cells were activated and driving these allergic reactions.

Cross-referencing data and integrating computational tools into the online ViPR resource allows complex analyses to be easily performed by researchers regardless of their bioinformatics training or expertise.

We intend to provide a few simple portals as a starting point, but new portals can be developed by anyone in the scientific or computational community, for a wide diversity of use cases, including: clustering, differential interference, spatial reconstruction, visualization, and graph - based analysis.

Dates: September 2015 — October 2017 Project Title: A high - throughput mathematical and computational model for mapping allosteric mechanisms by correlation analysis of residue - residue contacts

Data analysis and curation will be led by WTSI, with sharing of computational skills with Newcastle University.

The USAMRIID team was able to extend computational analyses that they had been using to track Ebola to the powerful dataset provided by the Broad and CDC.

He is interested in elucidating mechanisms of human disease by exploring the functional effects of genetic variation through computational analysis of «- omic» sequencing data.

We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly developed, web - based pipeline for real - time bioinformatics analysis on a computational server or laptop (MetaPORE).

Dr. Mullikin is a computational biologist, with mastery of developing computer programs for analyzing large data sets generated by systematic genome - analysis projects.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly developed, web - based pipeline for real - time bioinformatics analysis on a computational server or la

By using single - cell transcriptomics and computational analysis using a temporal mixtures of Gaussian processes model, termed GPfates, we reconstructed the developmental trajectories of Th1 and Tfh cells during blood - stage Plasmodium infection in mice.

Correlation of differentially expressed transcripts was detected by hierarchical clustering of expression values with the Cluster version 2.11 software [52] applying mean centering and normalization of genes and arrays before the computational clustering analysis.

New computational strategies are supported by our single cell data analysis experts with computational methods deconvolute tissue composition, determine cell type heterogeneity, identify novel cell type defining markers or track transcriptional dynamics.

Some of the topics investigated by this team include advanced materials, artificial intelligence, bio-engineering, biomimetics, computational science, earth system science, energy systems, fundamental physics, informatics, mission analysis or propulsion.

One investigation concerned a 20o8 article by Wegman protege Yasmin Said, Wegman himself and two others in Computational Statistics & Data Analysis (CSDA).

One of the most important points made in these papers concerning the reproducibility of computational analyses is that having the tools and techniques in hand isn't nearly enough by itself to get the job done..

By using computational analysis, we orchestrated the many parts that will go into the envelope to be highly efficient and cost effective.

But yes, on Mashey p 119 et seq, he looks at a paper by Said, Wegman et al published 2008 in the journal Computational Statistics & Data Analysis.

If laws were drafted in a syntax designed to allow for computational analysis of their outcomes, and if those codes were open source, and could be examined and tested by anyone, then we could build tools that allowed people to test how the law would react to given scenarios.

By reducing the untangling challenge to a well - known partition problem, we rigorously prove the computational complexity of shared send analysis.