Sentences with phrase «by damage to nerves»

These are caused by damage to nerves (due to the accumulation of homocysteine and methylmalonic acid) and low neurotransmitter levels (because of the impaired synthesis of methionine, a precursor of many neurotransmitters).

Not exact matches

The DOD - funded research will target the use of Sprint specifically for amputees suffering from moderate to severe neuropathic pain — chronic pain typically caused by nerve damage.

For years Ullman had suffered from nerve damage that makes it hard for him to walk (he moves around the offices by Segway).

Just as I started to come to grips with permanent nerve damage and an array of side effects caused by my treatments, another crisis struck.

Mackey persuaded a doctor to cut off his left index finger, which throbbed with pain from nerve damage caused by radiation treatments.

And it took some time for him to regain dexterity in his left hand after he persuaded a doctor to cut off the index finger, which throbbed with pain from nerve damage caused by radiation treatments.

The nerves in their side are palpable and they were only saved a damaging feat at Brighton by a daft tackle in the penalty area that allowed Rooney to bag a late leveller.

«Either this was a direct act by the Russian state against our country, or the Russian government lost control of this potentially catastrophically damaging nerve agent and allowed it to get in the hands of others,» May said.

Mrs May said: «Either this was a direct action by the Russian state against our country, or the Russian government lost control of its potentially catastrophically damaging nerve agent and allowed it to get into the hands of others.»

«Moving to non-invasive and repeatable methods of nerve fiber measurements such as in vivo corneal confocal microscopy would enhance study of peripheral neuropathy by enabling early detection of damage, progression of nerve fiber deterioration, and enable assessment of therapeutic strategies in the SIV / macaque model,» explains Dr. Mankowski.

Studies have shown that corneal nerve fiber density, measured by confocal microscopy, can predict diabetes - related damage to the peripheral nerves, called peripheral neuropathy.

Neutrophils are one of the most common types of immune cells and known to engulf microorganisms, but they are not normally associated with peripheral nerve damage, such as that caused by diabetes or trauma.

Tear samples from patients with diabetes show elevated levels of substance P, which are related to early damage to the corneal nerves, which may contribute to the development of corneal ulcers and poor wound healing in patients with diabetes, according to the pilot study by Maria Markoulli, PhD, MOptom, FAAO, and colleagues of University of New South Wales, Sydney, Australia.

But their prominence at sites where nerve cells are damaged by the disease means they deserve careful scrutiny in the desperate search for ways to arrest the most salient cause of dementia.

Arthur Neufeld and his colleagues at Washington University in St. Louis are among the labs looking for ways to block the nerve damage caused by the pressure buildup.

Blocking the activity of a single enzyme can nearly halt the nerve damage caused by glaucoma in mice, according to a paper in the current issue of the Proceedings of the National Academy of Sciences.

«Our data clearly showed that one of the protein receptors on white blood cells called CXCR3 brings white blood cells to the optic nerve in response to production of its binding partner CXCL10 by damaged nerve tissue,» said Zhang.

Their findings, reported June 17 in the journal Neuron, could lead to treatments for chronic pain conditions caused by nerve damage, such as diabetic peripheral neuropathy (DPN) and post-herpetic neuralgia (PHN), as well as chronic inflammation, like rheumatoid arthritis.

Plaque hinders neuronal activity by gumming up synapses (spaces between cells through which chemical or electrical information is transmitted), eventually damaging nerve cell branches and leading to neuronal death.

«However, the capillary constriction produced by pericytes may, by restricting the blood supply for a long time, cause further damage to nerve cells even after the clot is removed.

They are too close to spinal nerves and tissue structures that could be damaged by another operation.

Arising from the Schwann cells of the vestibular (balance) nerve, these tumors can grow to the point of damaging nearby structures — and can lead to death by compressing the brainstem.

Celiac disease, which results from a sensitivity to gluten, was associated with a 2.5-fold increased risk of neuropathy (nerve damage), according to an article published online by JAMA Neurology.

But if the HLA - A2 gene turns out to be the culprit, then the immune system is probably involved somehow in Alzheimer's symptoms, says Payami, perhaps by damaging nerve cells.

RIPK1, the researchers found, inflicts damage by directly attacking the body's myelin production plants — nerve cells known as oligodendrocytes, which secrete the soft substance, rich in fat and protein that wraps around axons to support their function and shield them from damage.

A leading cause of blindness in the world especially for the elderly, glaucoma is caused by high intra-ocular pressure in the eye which then leads to damage to the optic nerve.

By linking the data, CTD was able to connect the dots and find genes that that may be key to connecting the drug and the possibility of nerve damage.

Ivermectin, the established drug which successfully treats the infection, is known to be effective against minor damage caused to the front of the eye by the worm, but until now scientists had very little clear evidence about the drug's role in preventing more serious effects of infection, in particular damage to the optic nerve.

«We found that the KPro leads to high levels of TNFa, and that by blocking TNFa, we can prevent the nerve damage.»

Now used by millions of people with Type 2 diabetes, the drug helps to protect patients from diabetes - related complications, including blindness, kidney failure, and nerve damage.

However, when the researchers genetically removed syntaphilin from the nerve cells, mitochondrial transport was enhanced, allowing the damaged mitochondria to be replaced by healthy mitochondria capable of producing ATP.

A study by researchers at Henry Ford Hospital found «substantial evidence» that a regenerative process involving damaged nerve fibers in the spinal cord could hold the key to better functional recovery by most stroke victims.

«How cells adapt to help repair damage: Genetic processes that allow cells to transform so they can mend damaged nerves have been identified by scientists.»

Genetic processes that allow cells to transform so they can mend damaged nerves have been identified by scientists.

To prevent collateral damage to precious nerve cells during immune skirmishes, the brain and spinal cord are tightly sealed off from the rest of the body by the blood - brain barrieTo prevent collateral damage to precious nerve cells during immune skirmishes, the brain and spinal cord are tightly sealed off from the rest of the body by the blood - brain barrieto precious nerve cells during immune skirmishes, the brain and spinal cord are tightly sealed off from the rest of the body by the blood - brain barrier.

She added that it will not be possible to restore vision to the woman's eye, because her optical nerves were too damaged by her injury.

She reports researcher Ippazio Antonazzo proposing several possible explanations, including nerve damage caused by diabetes making it more difficult for a person to sense migraine pain, or some treatment normalising the activity of insulin, making migraines less likely.

Now, Professor Martin and colleagues have discovered that in response to specific types of cell damage, Parkin can trigger the self - destruction of «injured» nerve cells by switching on a controlled process of «cellular suicide» called apoptosis.

The Sheffield team led by Dr Kurt De Vos and Dr Andy Grierson investigated the role of the C9orf72 protein in nerve cells and found it regulates the initiation of a vital process called «autophagy», which helps the cell to dispose of damaged proteins and cell parts, and recycles cell nutrients.

This damages nerve cells by blocking their ability to make the proteins needed for synaptic function and leads to the death of neurons in the brain and spinal cord.

The researchers set about trying to prevent this nerve damage by giving mice NR before or after exposing them to loud noises.

This research points to exciting new possibilities for preventing or reversing the disabling vision loss caused by age - related macular degeneration, diabetic retinopathy, retinitis pigmentosa, glaucoma, and other diseases that damage the retina, the layer of light - sensitive nerve cells that line the back of the eye.

Every day, week, month that goes by, there's further nerve damage,» said Jocelyn Duff, who lives in Massachusetts and started Cure CMT4J, a nonprofit foundation to find a cure for her daughter, Talia.

By this, researchers demonstrated that a peripheral nerve injury in rats would send a message from the damaged nerve cell to special spinal cord immune cells called «glial cells».

The new report, co-authored by several international research groups and led by Karolinska Institutet, shows that stem cells transplanted into damaged or threatened nerve tissue quickly establish direct channels, called gap junctions, to the nerve cells.

Current clinical gold - standard methods for assessing the structural integrity of nerve fibers damaged by glaucoma are only able to detect complete loss of those fibers from the retinal layer within the eye.

Studying owl monkeys and squirrel monkeys, he found that damage to a nerve, or loss of one or two fingers caused the portion of the map that had lost its input to be overtaken by neighbouring maps, as neurons in the affected area became responsive to other areas of skin.

Dr. Arthur Brown and his team are boosting nerve growth in the injured spinal cord by enhancing the nervous system's natural ability to rewire damaged circuits.

Previous work by others had shown that nerve damage, or limb amputation, led to a reorganisation of neuronal pathways in the cortex of very young animals.

We are very excited by the potential of this material for cardiac applications but the capacity of the material to deliver physiological electrical stimuli while limiting infection suggests it might have potential in a number of other indications such as repairing damaged peripheral nerves or perhaps even spinal cord.