Sentences with phrase «by development delays»

It's not clear whether the launch has been hampered solely by financial constraints or also by development delays.

Not exact matches

Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational changes; (11) the anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.

Our results may be affected by our ability to successfully market both new and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing our products and global economic conditions.

Among the factors that could cause actual results to differ materially are the following: (1) worldwide economic, political, and capital markets conditions and other factors beyond the Company's control, including natural and other disasters or climate change affecting the operations of the Company or its customers and suppliers; (2) the Company's credit ratings and its cost of capital; (3) competitive conditions and customer preferences; (4) foreign currency exchange rates and fluctuations in those rates; (5) the timing and market acceptance of new product offerings; (6) the availability and cost of purchased components, compounds, raw materials and energy (including oil and natural gas and their derivatives) due to shortages, increased demand or supply interruptions (including those caused by natural and other disasters and other events); (7) the impact of acquisitions, strategic alliances, divestitures, and other unusual events resulting from portfolio management actions and other evolving business strategies, and possible organizational restructuring; (8) generating fewer productivity improvements than estimated; (9) unanticipated problems or delays with the phased implementation of a global enterprise resource planning (ERP) system, or security breaches and other disruptions to the Company's information technology infrastructure; (10) financial market risks that may affect the Company's funding obligations under defined benefit pension and postretirement plans; and (11) legal proceedings, including significant developments that could occur in the legal and regulatory proceedings described in the Company's Annual Report on Form 10 - K for the year ended Dec. 31, 2017, and any subsequent quarterly reports on Form 10 - Q (the «Reports»).

«Many investors expected a more lengthy FDA review process of the JCAR015 trial (and potentially other CAR - T programs) and feared that a higher - degree regulatory scrutiny could increase the development risk of CAR T cell,» Leerink Research said in a note co-authored by analysts Michael Schmidt, Ph.D., Jonathan Chang, Ph.D., and Varun Kumar, Ph.D. «While it may take several weeks to reopen all clinical sites of the ROCKET trial, we believe the trial shouldn't be delayed by more than ~ 3 months.»

If we are required by the FDA, the EMA, or other regulatory authorities to perform studies in addition to those we currently anticipate, or if there are any delays in completing our clinical trials or the development of our current product candidates, our expenses could increase and our ability to generate revenue could be further delayed.

Any focus on (business development) is somewhat delayed by resolution of that,» CEO Ian Read told analysts.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

This phenomenon is said to be caused by a delay in phonological development for one or both of the twins.

If they aren't walking by 18 months it is officially classed as «delayed», but it's still nothing to worry about if your health visitor is happy with their development.

If not, giving them a smartphone will only delay social development by providing a way to isolate.

Fortunately, by the time we're toddlers, these delays all seem to disappear no matter how your baby sleeps, so it likely more appropriate to describe these kids as having a «lag» in their development and not a true delay.

Fortunately, by the time they were toddlers, these delays all seem to disappear no matter how your baby sleeps, so it likely more appropriate to describe these kids as having a «lag» in their development and not a true delay.

Fortunately, by the time they were toddlers, these delays all seem to disappear no matter how your baby sleeps, so it's likely more appropriate to describe these kids as having a «lag» in their development and not a true delay.

Potty training is an important milestone in your child's development and you do not want to delay their growth by not potty training them.

That would account for numerous respiratory issues listed above, and because the brain's supply of oxygen would be compromised by any of these, the delay in neurologic development is highly feasible as a result.

The authors concluded that sleep position significantly affects early motor development, but that the differences in milestone achievement were not characterized by delays.

By involving people in the planning process, and letting us all play a part in determining the way a place changes, people will help shape their future, and authorities are less likely to receive objections that may delay or halt development.

In language that seems calibrated to knock at Cuomo's soft spots for economic development and government accountability, the group writes that the economy of the state is being hurt by the delay and claim that member companies are now «exhausted» when it comes to trusting the state.

Law said in an interview the requirement would reduce the number of nuisance appeals by requiring those who appeal «to have skin in the game in a process that can delay development projects by two years or more.»

Recommendations on how to go forward with some of Gov. Andrew Cuomo's economic development contracts tainted by scandal have been delayed for another few weeks, the governor's economic development chairman said.

(This used to say that an article about Rep. Maurice Hinchey and his ties to Saugerties development projects planned by the Kingston Freeman had been «delayed» pending the confirmation of «an element of the story»... unsure why it's not appearing for some readers.

Other positive developments include a recent ruling by the Court of Appeal allowing trial judges to explain to jurors why a victim would have delayed reporting a rape to police, helping to alleviate the influence of the rape myth.

Mr. Zumapkeh said the District's dire financial challenges have been compounded by delays in releasing the area's share of allocations to the District Assemblies» Development Fund for the 2012 fiscal year.

He said he called a staffer this morning to contact Gov. Andrew Cuomo's administration and ask for a delay of today's vote by the Empire State Development board.

By the time DiNapoli's audit was released in August 2014, the development had been delayed by approximately three years — primarily due to the same zoning issues DHCR's staff had expressed concern about when it gave the project a low scorBy the time DiNapoli's audit was released in August 2014, the development had been delayed by approximately three years — primarily due to the same zoning issues DHCR's staff had expressed concern about when it gave the project a low scorby approximately three years — primarily due to the same zoning issues DHCR's staff had expressed concern about when it gave the project a low score.

Due to these actions by the Governor, after years of delay ground is expected to be broken next week on this valuable economic development for New York.»

The final deal did not include a delay for the development of a new teacher evaluation system, meaning districts who are not able to meet the requirements by the November deadline will have to apply for a waiver.

The governor's proposal would 1) prohibit state sales tax abatements unless a project is in a specific industry eligible for Excelsior tax credits (think «bureaucracy» and «hurts small business» here...), 2) require additional approvals by the relevant Regional Economic Development Council (REDC) and Empire State Development (think «unnecessary oversight and delays» here...), and 3) shift the abatement of state sales tax to a refund that might be issued sometime down the road (think «uncertainty» and «cashflow» here...).

Sammakia has sought to reign in the wide - ranging economic development activities undertaken by Kaloyeros across the state, while other programs and deals that would have brought the school significant revenue were discontinued or delayed.

Construction of the DeWitt facility was delayed at least a year by a federal corruption probe of state contracts, including Cor Development Co.'s contract to build the Soraa plant.

So, yes, dictatorships, in some circumstances, are unique in increasing the efficiency of governance by reducing delays in the formulation and implementation of policies due to the absence of the need for consensus and endless debates to implement projects or policy and the unique ability to calibrate complete legal systems by decree and even an ability to stay focused over long periods, accelerating economic development.

The Department of Housing Preservation and Development has allowed as many as 1,131 properties lie idle, with some sites largely abandoned, and many others where projects have been severely delayed, according to an audit by the office of Comptroller Scott Stringer.

Because there is still no accepted biomarker for aging, the drug's success would be judged by whether it can delay the development of several diseases whose incidence increases dramatically with age: cardiovascular disease, cancer, and cognitive decline, along with mortality.

Racial differences in parents» reports of concerns about their child's development to healthcare providers may contribute to delayed diagnosis of autism spectrum disorder (ASD) in black children, according to a study led by Georgia State University.

This study offered insight into delayed ASD diagnosis in black children by examining whether the concerns parents reported to providers about their child's development prior to diagnosis differed based on a parent's race.

With only one drug specifically approved for the treatment of lupus in the past 50 years, lupus patients are commonly treated with steroids, a class of immunosuppressive drugs that delay the development and progression of the disease by suppressing the immune system.

«One: those who «pass» may think that they are without evidence of eye disease though they may be «false negative» and might delay in seeking care with the development of symptoms, thinking that they had already had an eye exam, and, two, those under the care of an eye doctor may perceive a different situation than their doctor has described,» Lee said by email.

«These features might be down to the particularly harmful effects of alcohol on young brains that are still in development, perhaps by delaying neuromaturational processes,» says López - Caneda.

This mutation replicates the genetics of Coffin - Siris syndrome, a disorder that some patients with defects in the ARID1B gene have that is characterized by speech and social development problems, intellectual disability, and delayed physical growth.

During the study, all the lake's male fathead minnows began producing eggs and VTG, the female fish's egg development became delayed, newly hatched fish disappeared, and by the end, minnows were all but locally extinct.

Last year, the Department of Energy delayed a decision on whether to approve the experiment by two years to allow for more exploratory research and development.

Transition from vegetative to reproductive development was also observed by 11 DAS (Supplemental Figure 2E); however, subsequent developmental progression was delayed after 14 DAS in the mutant.

Their lives are constantly under threat by the risk of SUDEP — and they never outgrow their condition, which delays their development and often requires round - the - clock monitoring and care.

Our goal is to kick - start the drug discovery process as early as possible by removing translational delays in the transition of drug development from bench to bedside.

The peripheral sink Aβ hypothesis indicates that the peripheral clearance of Aβ and its regulation by dietary phytosterols is of substantial interest since it may delay hypercholesterolemia and the early onset of amyloid plaque development.

by dietary phytosterols is of substantial interest since it may delay hypercholesterolemia and the early onset of amyloid plaque development.

The second video also suggests that soy milk may promote health and reduce the risk for future breast cancer by delaying pubertal breast development.

Gore Verbinski (Pirates of the Caribbean) boarded the long - delayed Channing Tatum project early this month, a development swiftly followed by the studio's announcement of a Feb. 14, 2019, release date.

It should be mentioned that this possibility was hinted at by Aonuma several times during the development of Wind Waker HD, so while it is a rumor, we're considering it highly likely, especially with the delay of new Legend of Zelda title for Wii U.