Sentences with phrase «by drug»

Major Neurocognitive Disorder is diagnosed when disturbance of a single cognitive ability is severe enough to interfere with independence, and the disturbance is not caused by drug use, delirium, or various other medical or psychiatric conditions.

In either case, the charity will receive a share of any future revenues generated by the drug.

Researchers said the ability to record those two functions would be useful to pharmaceutical companies because it could alert drug manufacturers to cardiac problems caused by a drug early in the process before reaching the clinical trial stage.

As the TRAC study sites were selected to target areas of emerging resistance, samples will include parasites that are artemisinin resistant alongside sensitive parasites — those that are more easily killed off by the drug.

The possibility of using novel drug delivery systems for known and new antibiotic drugs opens the way to an innovative management of infections caused by drug resistant bacteria, which are otherwise difficult to treat.

He will be looking at mouse models of osteoporosis and determining whether reducing mTOR signaling (induced by the drug rapamycin) influences age - related bone loss.

When they mate with other strains, their winning tickets break up and their offspring are wiped out by the drug.

Emulate's founders have spent years paving a path to widespread acceptance of organs - on - chips by both drug industry leaders and the FDA, whose trust in the models is essential for their success.

This is necessary for example to check what structural changes might be induced by a drug binding to a target.

Growth of osteosarcoma cells was inhibited by this drug by targeting of multiple signal transduction pathways [41].

Current studies in the Parsons laboratory are investigating whether binge patterns of drug consumption evoke similar endocannabinoid disruptions, and they are probing the influence of impaired endocannabinoid signaling in the excessive motivational effects produced by drug - associated conditioned cues.

All this is necessary to comply with rules imposed by the Drug Enforcement Agency to make sure drugs meant for research don't end up on the street, says Heike Newman, a senior regulatory manager at the University of Colorado's Anschutz Medical Campus, where Lindley's study will take place.

How well are Parkinson's symptoms being controlled by a drug?

They write, «This real - world, almost paradoxical, phenomenon demonstrates the complexity inherent in the treatment of addictive disorders — a medication intended to treat substance use disorder that has its own abuse potential, upon gaining popularity and increased availability, will inevitably be explored by drug abusers for reward and reinforcement purposes.»

Curiously, whereas TORC1 is inhibited by rapamycin, TORC2 is unaffected by this drug.

Others say what is needed is a proper assessment weighing the real harms caused by the drug and, crucially, of the harms that criminalisation could cause.

«It gives credence to the concept that like cancer cells, HIV - infected cells can be targeted and eliminated by a drug.»

Coffey is part of a trial sponsored by the drug company Pfizer awaiting approval in the United Kingdom that will slip a patch of hESC - derived RPE cells under the retina instead of injecting them in a liquid suspension.

So a Mexican ecology graduate student spent 1.5 years traipsing through that country, combing through dense jungles and braving areas controlled by drug cartels to net more than 900 of the nocturnal creatures.

«If we can find a way to target those neurons in humans, maybe we can reduce the «high» produced by the drug and reduce the withdrawal symptoms,» said Olivier George, assistant professor at TSRI and senior author of the new study.

«As prohibitions on marijuana ease and sales of marijuana become more visible, it's important to think about how we need to change the way we talk to young people about the risks posed by the drug,» said Elizabeth D'Amico, lead author of the study and a senior behavioral scientist at RAND, a nonprofit research organization.

But cells from patients who hadn't been helped by the drug remained hyperexcitable.

The majority of the health care costs of AD patients, i.e. 78 - 84 per cent, were caused by hospital care and only a fraction by drug therapy.

«Cognitive functioning overwhelmingly falls within the normal range,» the report states, while adding that researchers» pre-existing assumptions about meth's detrimental effects «should be reevaluated to document the actual pattern of cognitive effects caused by the drug.»

The presentation will discuss how Dr Humphrey and his team showed that cancer cells with a mutated SETD2 gene were killed by a drug called AZD1775 that inhibits a protein called WEE1.

Other infectious disease experts are impressed, not only by the drug discovery but also by the possibility that this is just the beginning.

Methicillin - resistant Staphylococcus aureaus, commonly known as MRSA, is a major cause of hospital - acquired infections, and the second biggest cause of death by drug - resistant bacteria in the US.

The need to run trials in children is also being addressed by drug companies.

Seven other states (California, Colorado, Georgia, Mississippi, Nebraska, New York, Washington) have age - restriction criteria that vary by drug entity.

«Evidently, beneficial organisms not affected as much by the drug, such as earthworms, were apparently able to compensate for the loss of other organisms,» sums up Blanckenhorn.

«Prescription drugs are seen as blessed by a trusted institution, the FDA, while increasingly aggressive advertising by drug companies simultaneously floods parents and children with messages that these substances are safe, popular, and beneficial.»

The overdose would have killed her, she says, had she not been brought back from the dead by a drug that researchers call miraculous, but that the public largely hasn't heard of.

The researchers also found that using their new method, measures of motivation accurately predicted relapse behavior, which was not predicted by drug - taking itself when low effort was required.

First, the study is based on data from only six states where this information is captured; secondly, the effects of drugs on driving performance and crash risk vary by drug type, dosage, and the driver's physiological response and tolerance level.

The project, which has been running for more than two years, employs some of the same methods used by drug companies.

For example, perhaps the amino acid interactions that stabilize the pump structure could be targeted by drug development efforts to block pump assembly or function, thereby rendering currently defunct antibiotics effective once more.

These same tools can potentially be used by drug companies to identify new targets for treating many diseases and conditions.

Once exposed, the switch can be activated by a drug called ABT - 263.

«It's caused by the drug doctors are giving.

We refer to these as «alerts»: they can be used by drug design experts to try to avoid certain interactions and / or structures in order to develop safer drugs,» says Aloy.

Begun in April 2010, it was funded by the drug's manufacturer, Merck of Whitehouse Station, N.J.

Stamp bags are small wax packets that contain mixtures of illicit drugs, most commonly heroin, packaged for sale and sometimes stamped with a graphical logo by drug dealers to market their contents.

Much of her writing from that time, reprinted and updated in this book, covers the ideas of controversial University of California at Berkeley biologist Peter Duesberg, who hypothesizes that AIDS is not caused by HIV but by drug use or poverty.

All ten groups were reflected in the dossier compiled by the drug manufacturer, but the data were informative for only three of these groups.

The odds are five times greater that a study sponsored by a drug company will support its own product than would a noncommercially funded study.

According to press reports, a cancer patient who received Pfizer's antifungal drug Vfend swears he saw a Wookiee leaning over his bed — a hallucination brought on by the drug.

This response was blocked by a drug that inhibits the complement system, a part of the non-specific immune system present in human blood.

This wariness of bias is echoed by Iain Chalmers, one of the founders of the Cochrane Foundation, who in 2013 cautioned in the BMJ: «There is clear and consistent evidence of under - reporting and manipulation of the scientific literature by the drug and devices industries, and industry sponsors most of the world's clinical trials» (doi.org/w3w).

Since then, she has had just one seizure, in late May, and that was caused by a drug interaction.

About 70 percent of those are infected by drug - resistant bacteria.