For example, perhaps the amino acid interactions that stabilize the pump structure could be targeted
by drug development efforts to block pump assembly or function, thereby rendering currently defunct antibiotics effective once more.
Not exact matches
Among these deaths are many that could be prevented
by concentrated
efforts in the research,
development and distribution of new
drugs.
«Techniques like this one that enable controlled, remote C - H activation are just beginning to be adopted
by industry, and should provide a boost to
drug discovery and
development efforts for many years to come,» Yu said.
Pharmaceutical companies,
by contrast, focus most of their
efforts at the other end of the
drug development pipeline, moving potential
drug compounds through human clinical trials into the market.
More importantly, says Greenberg, the BRCC36 - KIAA0157 complex may represent an attractive
drug development target for inflammatory diseases — an
effort that should be aided immeasurably
by the detailed structural information this study provides.
Jointly published
by WHO, the United Nations
Development Programme, and the United Nations Office on
Drugs and Crime, the report reviews the current status of violence prevention
efforts in countries, and calls for a scaling up of violence prevention programmes; stronger legislation and enforcement of laws relevant for violence prevention; and enhanced services for victims of violence.