The age of the billion - dollar blockbuster drug is most likely passing, to be replaced
by drugs with genetically targeted markets.
In the 1970s this State decided to punish those who were trapped
by drugs with long prison terms.
Not exact matches
That could help curtail a true
drug crisis
with devastating economic and social impacts — and which was sparked, in large part,
by the actions of huge pharmaceutical companies.
With city data indicating that African - Americans have been charged with marijuana crimes twice as frequently as white residents, the Oakland City Council voted unanimously in March to allocate 50 percent of medical marijuana and cannabis sales permits to people affected by the war on dr
With city data indicating that African - Americans have been charged
with marijuana crimes twice as frequently as white residents, the Oakland City Council voted unanimously in March to allocate 50 percent of medical marijuana and cannabis sales permits to people affected by the war on dr
with marijuana crimes twice as frequently as white residents, the Oakland City Council voted unanimously in March to allocate 50 percent of medical marijuana and cannabis sales permits to people affected
by the war on
drugs.
The reversal of the Cole Memo, written
by then - Deputy Attorney General James M. Cole in 2013 means that there will be more confusion about the legality of growing, selling, and using the
drug in places where state and local laws clash
with the federal government.
But sales of Praluent and a rival Amgen
drug,
with list prices of more than $ 14,000 a year before discounts, have been severely constrained
by onerous roadblocks to patient access
by insurers.
But sales of Praluent and a rival Amgen
drug,
with list prices of more than $ 14,000 a year before discounts, have been constrained
by onerous roadblocks to patient access
by insurers.
CASIS's mission is to encourage «use of this unparalleled platform for innovation» — and Merck is taking this to heart
by experimenting
with drug development in the realm of microgravity.
Combining the traditional world of shipping
with the new world of data, it helps governments reduce the trafficking of arms,
drugs and people; and saves lives
by predicting and preventing accidents.
The hep C treatment is being developed
by the
Drugs for Neglected Diseases Initiative (DNDi) in collaboration
with Egyptian
drug maker Pharco Pharmaceuticals.
I think it's part of the broader IPO window, and is being driven
by some of the returns that have been found in the biotech world
with really successful
drugs.
Topics included: early reporting on inaccuracies in the articles of The New York Times's Judith Miller that built support for the invasion of Iraq; the media campaign to destroy UN chief Kofi Annan and undermine confidence in multilateral solutions; revelations
by George Bush's biographer that as far back as 1999 then - presidential candidate Bush already spoke of wanting to invade Iraq; the real reason Bush was grounded during his National Guard days — as recounted
by the widow of the pilot who replaced him; an article published throughout the world that highlighted the West's lack of resolve to seriously pursue the genocidal fugitive Bosnian Serb leader Radovan Karadzic, responsible for the largest number of European civilian deaths since World War II; several investigations of allegations
by former members concerning the practices of Scientology; corruption in the leadership of the nation's largest police union; a well - connected humanitarian relief organization operating as a cover for unauthorized US covert intervention abroad; detailed evidence that a powerful congressional critic of Bill Clinton and Al Gore for financial irregularities and personal improprieties had his own track record of far more serious transgressions; a look at the practices and values of top Democratic operative and the clients they represent when out of power in Washington; the murky international interests that fueled both George W. Bush's and Hillary Clinton's presidential campaigns; the efficacy of various proposed solutions to the failed war on
drugs; the poor - quality televised news program for teens (
with lots of advertising) that has quietly seeped into many of America's public schools; an early exploration of deceptive practices
by the credit card industry; a study of ecosystem destruction in Irian Jaya, one of the world's last substantial rain forests.
Indeed, say the BW authors, «orphan
drugs accounted for a disproportionate share, 41 percent, of all medications brought to market in 2014» —
with global sales,
by one estimate, expected to reach $ 209 billion
by 2022, roughly twice what they are now.
Theranos» labs have been evaluated and deemed acceptable
by drug companies, hospitals that work
with them, Walgreens, and other entities.
GLP - 1
drugs are used to better control blood sugar levels in people
with type 2 diabetes, and are better known
by the brand names: Victoza, Byetta, and Bydureon.
But the initiative comes
with another huge financial prize for firms that successfully win FDA approval for these niche therapies: a priority review voucher that can be used to slash the regulatory period for a different experimental specialty treatment being developed
by a
drug maker or, more often, sold for potentially hundreds of millions of dollars to another pharma company.
These risks and uncertainties include, among others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic
drug manufacturers; data from clinical trials may be interpreted
by the FDA in different ways than we interpret it; the FDA may not agree
with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization
by the proprietary rights of third parties, or have unintended side effects, adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made
by the company
with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
Strikingly, for all the media attention on the case (propagated
by Shkreli's troll - y Twitter antics and relish for stirring the pot), the trial verdict had nothing to do
with the
drug price hike that thrust him into the national limelight.
By virtually every measure, prohibition of cannabis
with high THC commonly known as marijuana and the variant
with no recreational
drug potential commonly known as hemp has cost the U.S. economy billions of dollars in missed business opportunities and wasted resources spent unsuccessfully fighting the so - called war on
drugs.
Dr. Nir Barzilai, the director of Institute for Aging Research at the Albert Einstein College of Medicine in New York, has been researching the
drug,
with the hopes of one day getting it approved as an anti-aging treatment
by the FDA.
The chain, owner of various grocery and Shoppers
Drug Mart stores across the country, announced Thursday that it aims to remove triclosan and phthalates, along
with microbeads, from all of its Life Brand and President's Choice products
by the end of 2018.
After that, Watson will take assist
by providing both physician and patient
with a report that includes the most relevant
drug trial and academic studies for their specific conditions.
Taking dangerous quantities of the otherwise safe loperamide is one strategy being used
by people addicted to opioid painkillers and other
drugs since it can increase opioid absorption in the gut; the FDA says it is now working
with loperamide manufacturers to change its packaging so that it comes
with fewer doses and is thus harder to abuse.
The Food and
Drug Administration (FDA) is working
with manufacturers to tweak the packaging of loperamide, a common OTC and prescription anti-diarrhea medication that is now also being used
by people addicted to opioids to stem withdrawal symptoms or enhance their highs.
The move comes nine months after the Cherokee Nation sued Walmart and two major pharmacies, Walgreens and CVS Health, along
with large
drug distributors, for allegedly profiting
by «flooding» Native American areas in Oklahoma
with prescription painkillers.
As lawmakers and the public scrutinize dramatic price increases for other old
drugs — most recently
with the Mylan - owned EpiPen, which saw its cost go up
by 500 % in the past nine years — the next flash point may be insulin, a
drug both ubiquitous and complicated.
But further analysis released
by the public health agency Friday highlight two alarming trends for U.S. mortality: significant rises in gun and, especially,
drug overdose deaths (
with the latter driven
by the ongoing opioid crisis in America).
AmpliPhi and Adaptive Phage Therapeutics have successfully treated more than two dozen patients
with life - threatening conditions and are currently treating a few others under an emergency use authorization granted
by the US Food and
Drug Administration.
Fortescue Metals Group's Christmas Creek iron ore mine site has been raided for
drugs by WA Police, working in cooperation
with the company, as part of a crackdown of mine sites across the state.
One notable exception is the U.S. Food and
Drug Administration's announcement that food outlets
with more than 20 locations must list calorie counts on their menus
by December 2016.
«We have an agreement
with them where we own the
drug, but anything that's funded
by the U.S. government, it reserves the right to use that under certain circumstances,» says Mark Murray, president and CEO of the Burnaby, B.C., company.
The memory - eating disease, expected to afflict 15 million Americans
by 2060 (and tens of millions more around the world as life expectancy increases), has no cure; a new
drug for the condition hasn't been approved in well over a decade; initially promising experimental treatments seem to be failing
with clockwork regularity; and there's not even a definitive consensus on what, exactly, biopharma companies should focus on while developing Alzheimer's medicines.
Intarcia has completed several late - stage clinical trials in which it uses the pump to deliver a glucose - controlling
drug continuously for months — an idea, that if successful (and approved
by the FDA) could significantly help patients
with type 2 diabetes, fewer than half of whom maintain the recommended glycemic levels.
KFC, China's biggest restaurant chain
with more than 4,000 outlets and plans to open 700 more this year, was hit hard
by a report in December 2013 that some poultry suppliers violated rules on
drug use in chickens.
On the heels of rival diabetes
drug maker Novo Nordisk's announcement that it will limit branded
drug price hikes to the single digits going forward, U.S. pharma giant Eli Lilly announced Tuesday that it is partnering
with benefits manager Express Scripts and a mobile health platform hosted
by Blink Health to slash patients» insulin costs.
Vincent Ramos, the CEO of the company, along
with four associates were accused on Thursday
by the Department of Justice (DOJ) of «knowingly and intentionally conspiring
with criminal organizations
by providing them
with the technological tools to evade law enforcement and obstruct justice while committing transnational
drug trafficking.»
There's been a recent trend in biopharma where some companies, led
by Allergan (agn) CEO Brent Saunders» new «social contract»
with patients, are voluntarily pledging to limit
drug price hikes and being more transparent about which products have seen price increases.
«US - based Mexican [transnational criminal organization] members generally coordinate the transportation and distribution of bulk wholesale quantities of illicit
drugs to US markets,» the DEA report states, «while retail - level distribution is mainly handled
by smaller local groups and street gangs not directly affiliated
with Mexican TCOs.»
Cryptocurrency Billionaire, 53, Dies in
Drug Rehab in Mexico After Battle
With Addiction,
by Alana Abramson
Central American groups, as well as the Sinaloa cartel and other Mexican groups, have previously formed arrangements
with gangs in the port city of Liverpool to bring in
drugs by sea, typically from Venezuela and Ecuador, according to The Times.
At 16 years old, I was a full - blown
drug addict who was completely throwing his entire life away
by living a life
with no meaning and surrounding myself
with others who degraded my potential and ability to become the best version of myself.
The commission that is setting up the system in Massachusetts recently passed new rules that bar anyone
with a felony
drug trafficking conviction from getting licensed
by the state to cultivate or sell legal marijuana.
By printing multiple lung airways — or any other afflicted organ — from a human patient and testing
drugs on them, pharma companies can bypass the ethically challenged practice of testing on animals and proceed to human clinical trials
with greater confidence the
drugs will actually work, according to Wadsworth.
Novo said it hoped to achieve a weight loss that can compete
with surgery
by combining semaglutide
with new biological
drugs.
Drug giant Johnson & Johnson has been hit
with a $ 417 million verdict in the latest trial focusing on alleged links between talc - based products like its Johnson's Baby Powder, use
by many for feminine hygiene, and ovarian cancer.
Crawford's death was confirmed
by the Toronto legal firm Osler, Hoskin & Harcourt where Crawford began as a corporate lawyer in the 1950s before leaving to pursue a career
with Imasco Ltd., a company that, at the time, owned Imperial Tobacco, Canada Trust and Shoppers
Drug Mart.
Home to the beach resort Acapulco, Guerrero was the scene of the September 2014 disappearance of 43 trainee teachers, who the government says it believes were massacred
by a
drug gang working
with corrupt local officials and police.
That's particularly significant since people
with diabetes have a significantly higher risk of developing cardiovascular conditions — and Lilly's
drug was shown to cut the cardiovascular - related deaths in diabetes patients
by a staggering 38 % in clinical trials.
The cryptocurrency, originally championed
by hacking cliques who flew close to anarchism, has an association
with the «dark web» and shady forums where
drugs, sex, and other illegal products and services are bought and sold.
Approved
by the FDA in 2011 for metastatic melanoma, Yervoy was the first
drug to offer a survival benefit to patients
with that disease.