Since the deadly brew could be inactivated by boiling or adding protein - chopping enzymes — both of which destroy the function of proteins — Wang believes the «killing factor» released
by the dying cells is a protein.
Not exact matches
By killing himself in his prison
cell while awaiting appeal of a murder conviction, former National Football League tight end Aaron Hernandez essentially
died an innocent man under a Massachusetts law that once protected the assets of the late Enron CEO.
«We
die daily»: so it is often said, not only with reference to the death of our bodily
cells and their replacement
by other
cells every few years, but also in respect to our possible human growth.
Some fail even to implant themselves in the uterine wall; in my imagination, these little ones only a few days past the original combination of two
cells seem like motes in the air, floating through dust and sunbeams,
dying unnoticed
by any but God.
We all know
by now that if the atomic combinations break down, or if the proper chemical reactions fail to take place, the
cell will
die or the brain (in which thought seems to dwell) will fail to function, and «mind» will be impaired or it may vanish altogether.
The risks of
dying in a car accident hover somewhere around 1 in 17,000 — without considering drowsiness or distraction
by cell phones, etc..
Baby mice with NEC that were given breast milk after the onset of the disease had noticeably less severe forms of the condition, marked
by fewer gut
cells dying.
Behind those barbed wire walls, harmless old men
die in handcuffs, raped women are thrown in
cells by male guards who regularly enter unannounced.
Buffalo businessman and political activist Carl Paladino hopes President Obama contracts mad cow disease after having intercourse with a cow and
dies, while his advisor Valerie Jarret is killed
by «a Jihady
cell mate mistook her for being a nice person and decapitated her.»
«More women are postponing childbearing, but with age, the cumulus
cells that surround and nurture the eggs begin
dying; we've found that this is caused
by lack of oxygen,» said senior author Pasquale Patrizio, M.D., director of the Yale Fertility Center and professor in the Department of Obstetrics, Gynecology & Reproductive Sciences.
In humans, Huntington's is an inherited disease caused
by a gene encoding a toxic protein, called mutant huntingtin, which causes brain
cells to
die.
Huntington's disease is caused
by a gene encoding a toxic protein (mutant huntingtin) that causes brain
cells to
die.
Because heart
cells lose their ability to divide soon after we are born, when the
cells die — in a heart attack, say — the dead tissue is replaced
by scar tissue rather than new muscle.
Also known as the «Guardian of the Genome,» p53 fights cancer
by causing damaged
cells to
die or
by halting the growth of mutant
cells before they become cancerous and spread to the rest of the body.
Although the group didn't identify the toxin's target, it probably causes
cells to
die from within
by overstimulating the immune system, says immunologist Harry Hill of the University of Utah.
Using
cells from cadavers, doctors have been experimentally transplanting pancreatic islets into humans for decades, but as many as 60 percent of the transplanted islets
die immediately because they are cut off from their blood supply and are killed
by an immune response due to direct injection into the bloodstream, and those that survive the transplant usually
die within several months.
Published in the journal Frontiers in Neuroscience, the researchers have assembled strong evidence that the neurological decline common to these diseases is caused
by «auto - inflammation», where the body's own immune system develops a persistent inflammatory response and causes brain
cells to
die.
The tremors and other movement impairments of Parkinson's are triggered
by the death of dopamine - producing
cells in the brain, so the investigators used flies that had been genetically engineered to have their dopamine
cells die off as they age.
The release of several signals
by skin
cells that are
dying contributes to the creation and spreading of the chronic immune response and hyper - proliferation and irregular differentiation of epidermis,» says Joan Manils, first author of the study and member of the mentioned department and post-doctorate researcher at the Trinity Biomedical Sciences Institute (Ireland).
A new diagnostic test, created
by Detlev Riesner and colleagues at the Heinrich - Heine - Universitat in Dusseldorf, Germany, may help spot the plaques long before brain
cells die off.
Miceli, 43, had
died after being held in a
cell in the parish jail, bound to a metal bed
by five - point leather restraints.
The research team, led
by senior author Timothy P. Cripe, MD, PhD, chief of the Division of Hematology / Oncology / BMT at Nationwide Children's Hospital, found that virotherapy doesn't always require a strong virus infection of cancer
cells to cause tumors to shrink or
die.
The following year, a paper
by Ben Lehner's group at the Center for Genomic Regulation in Barcelona, Spain, drove the point home: When a
cell produces too many of these proteins, they found, it
dies.
Brains of people who
died from various diseases caused
by tangled tau had more dead and damaged
cells if the people carried APOE4.
Once these channels become blocked
by charybdotoxin, nerve
cells can not function and the scorpion's victim
dies a paralysing and painful death.
«The key assumption is that dead
cells that look the same probably
died by the same mechanism,» he said.
Tattoos can be removed
by laser pulses that cause skin
cells to
die and release their pigment, which can then be transported away from the skin and into the body's lymphatic system.
More recently, however, researchers have suggested that macrophages — specialized immune
cells that reside in the dermis — are attracted to the wound inflicted
by the tattoo needle and gobble up the tattoo pigment just as they would normally engulf an invading pathogen or piece of a
dying cell.
If an engineered organism mates with a wild counterpart, the transcription factors render the offspring unable to survive
by activating genes that cause their
cells to
die.
Mice with a form of dementia have had the condition reversed
by a process that involves «rebooting» brain
cells otherwise destined to
die.
One theory is that the glaciation was triggered
by the evolution of large
cells, and possibly also multicellular organisms, that sank to the seabed after
dying.
When a cancer
cell dies by apoptosis, the result is a neat and tidy process where the dead
cell's remains are «recycled,» not contaminating healthy
cells around them, and not inducing inflammation.
BCL - 2 is present in high amounts in many tumors and helps cancer
cells to survive, but when the BCL - 2 gene is blocked
by MM41 in mice, the cancer
cells succumb to apoptosis and
die.»
In healthy human
cells, the p53 protein helps prevent tumors
by putting the brakes on the
cell cycle to give an ailing
cell time to fix itself — or
die — rather than spawning more corrupted
cells.
In NASH, the liver becomes inflamed and criss - crossed
by fibrous scar tissue, and liver
cells start
dying.
However, in this case the target
cells were pigment ones, which eventually
die off to be replaced
by new ones.
She explained: «The number of
cells in our body are balanced
by the level at which
cells replicate and replace the ones that
die.
Egg
cells can also be preserved in their hundreds of thousands
by collecting ovarian tissue from reproductively active females that
die in captivity and dunking it in liquid nitrogen.
«Often things go wrong right away when stem or therapeutic
cells are injected into the body because some
cells can migrate, while other
dying cells are eaten
by the body and expelled,» says Xiao - an Zhang, an assistant professor of chemistry at U of T Scarborough.
So lethal was this virus to the HeLa
cells that nearly every
cell soon
died, overwhelmed
by the infection despite any protective effect from antibodies they harbored.
The researchers anticipate that the pigs could be a practical way to test treatments for HD, which is caused
by a gene encoding a toxic protein that causes brain
cells to
die.
Researchers in Germany have demonstrated that hematopoietic stem
cell (HSC) transplants can be improved
by treatments that temporarily prevent the stem
cells from
dying.
«The cancer stem
cells are also recovering during this gap period, induced
by PGE2 released from
dying cancer
cells
(Why it does this is unclear, but scientists believe it's a clever way for staph, which can't move
by itself, to spread beyond the molasses - like environment created when DNA leaks from infected,
dying cells.)
Cystine is responsible for maintaining high levels of antioxidants that disarm free radicals of oxygen; so when the researchers got rid of this nutrient, the cancer
cells essentially
died by their own hand of free radical damage.
The renowned embryologist charted the intricate architecture of the developing nervous system, proving that its final structure is shaped not just
by newborn
cells but also
by those that eventually
die.
With frontotemporal dementia the symptoms are caused
by dead and
dying cells; in depression the root cause is still unknown.
Retinal ganglion
cells only began to
die after they're affected
by high levels of zinc leaking from injured amacrine
cells.4
The pigment is needed
by photoreceptor
cells — the retina's light - sending rods and cones — and when RPE65 is mutated, the photoreceptor
cells gradually
die.
The drug, known as HRX9, works
by preventing the cancer
cells from avoiding apoptosis — the natural process
by which unhealthy and damaged
cells close themselves down and
die.