Sentences with phrase «by early life exposures»

Furthermore, interactions between the environment and the epigenome may provide mechanistic insight into many toxicological phenomena that are not well - understood, such as non-genotoxic carcinogenesis, age - based windows of susceptibility, developmental reprogramming by early life exposures, and trans - generational exposure effects.

Not exact matches

For the financial markets, those risks are compounded by the unbalanced «risk - on» exposure that investment managers and institutions adopted early this year, encouraged by a short - lived burst of economic activity, and faith in a central - bank backstop.

By setting the day's agenda with early morning tweets, followed by a string of television interviews and rallies that were televised live, Trump gained millions of dollars in free media exposure while his opponents «were running around doing fundraisers trying to raise enough money to buy an ad that could be run in between his interviewBy setting the day's agenda with early morning tweets, followed by a string of television interviews and rallies that were televised live, Trump gained millions of dollars in free media exposure while his opponents «were running around doing fundraisers trying to raise enough money to buy an ad that could be run in between his interviewby a string of television interviews and rallies that were televised live, Trump gained millions of dollars in free media exposure while his opponents «were running around doing fundraisers trying to raise enough money to buy an ad that could be run in between his interviews.

Our study shows that after that early programming state, after weaning, and after the lactation period, when we introduced a new type of diet it changed the epigenome in a way that actually affects metabolism and potentially will reduce some of the damage caused by an early - life high - fat exposure,» Pan says.

Here's the result that has gotten the most press: Academic research careers were less popular with the late cohorts than the early ones in all disciplines, suggesting, perhaps, that graduate students are disillusioned by exposure to the lives and careers of their faculty advisers.

The study also found that a lack of exposure in early life could not be compensated for by introducing the GF mice to a broader range of microbes in adulthood.

«Policy makers need to heed data such as those presented by Morales et al as limiting exposure to traffic - related pollution during fetal development and early postnatal life is one way that the burden of respiratory disease can be decreased.»

While earlier research established a link between parental conflict at a single point in time and children's adjustment later in life, Raver and her colleagues saw a need to explore how children may be adversely affected by prolonged exposure to this aggression.

Last summer, a panel of 38 researchers headed by vom Saal published a report in Reproductive Toxicology warning that BPA (much like the synthetic estrogen diethylstilbestrol, or DES) is a potential chemical time bomb that may lead to multiple problems, including a higher risk of cancer, especially if exposure occurs in the womb or an infant's early life and on an unrelenting daily basis.

Neuroscience research indicates that such «hidden hearing loss» caused by exposure to loud sounds in the early years deepens over the life span, worsening one's hearing ability later in life.

One avenue of our translational research aims to determine the impact of in utero HIV - 1 exposure on infant immunity to vaccinations and co-infections by dissecting the infant immune repertoire present at birth in the context of maternal HIV - 1 infection and how the infant T cell repertoire changes following early life exposures compared to infants born to the HIV - 1 uninfected women of similar socio - economic status.

Scientists are still trying to explain how this microbial diversity comes about, but it is likely influenced by factors including diet, environment, host genetics and exposure to microbes early in life.

Oppenheim speaks of growing up in Washington and California, his father's Russian ancestry and education in China, his father's career in engineering, his mother's background and education in English, living in Richmond El Cerrito, his mother's love of the arts, his father's feelings toward Russia, standing out in the community, his relationship with his older sister, attending Richmond High School, demographics of El Cerrito, his interest in athletics during high school, fitting in with the minority class in Richmond, prejudice and cultural dynamics of the 1950s, a lack of art education and philosophy classes during high school, Rebel Without a Cause, Richmond Trojans, hotrod clubs, the persona of a good student, playing by the rules of the art world, friendship with Jimmy De Maria and his relationship to Walter DeMaria, early skills as an artist, art and teachers in high school, attending California College of Arts and Crafts, homosexuality in the 1950s and 1960s, working and attending art school, professors at art school, attending Stanford, early sculptural work, depression, quitting school, getting married, and moving to Hawaii, becoming an entrepreneur, attending the University of Hawaii, going back to art school, radical art, painting, drawing, sculpture, the beats and the 1960s, motivations, studio work, theory and exposure to art, self - doubts, education in art history, Oakland Wedge, earth works, context and possession, Ground Systems, Directed Seeding, Cancelled Crop, studio art, documentation, use of science and disciplines in art, conceptual art, theoretical positions, sentiments and useful rage, Robert Smithson and earth works, Gerry Shum, Peter Hutchinson, ocean work and red dye, breaking patterns and attempting growth, body works, drug use and hippies, focusing on theory, turmoil, Max Kozloff's «Pygmalion Reversed,» artist as shaman and Jack Burnham, sync and acceptance of the art world, machine works, interrogating art and one's self, Vito Acconci, public art, artisans and architects, Fireworks, dysfunction in art, periods of fragmentation, bad art and autobiographical self - exposure, discovery, being judgmental of one's own work, critical dissent, impact of the 1950s and modernism, concern about placement in the art world, Gypsum Gypsies, mutations of objects, reading and writing, form and content, and phases of development.

Realized in loud, garish hues partly informed by the artist's early exposure to Socialist Realism, Rauch's enigmatic pictorial narratives never vanish into explanation: «My paintings have something vital about them, like an animal, a living thing,» he says.

The Spanish artist Jorge Peris was given early exposure to the Italian public at the 2005 Turin Triennale, where he turned a room into a living organism by covering the walls with live molds

Through our mission of Support - Education - Advocacy, we seek to improve the lives of children impacted by early childhood trauma, abuse and neglect, and prenatal exposures in their families, schools and communities.

The importance of early interventions that target caregiving is underscored by studies demonstrating high cost - effectiveness through greatly enhanced long - term outcomes.41 Furthermore, children who receive more nurturing caregiving may also be protected from exposure to stressful life events, suggesting this central target may have positive ramifications on brain development.42 Considering these issues, study findings are relevant to the public policy debate on the importance of early preschool programs for young children living in poverty.

Improvements in health visitors» sensitivity to abusive parenting may have enabled them to institute child protection proceedings at an earlier stage in the child's life, reducing the length of exposure to damaging environments by placing infants with substitute parents during the first year of life.

In animals, physiological hyperreactivity induced by exposure to early - life adversity can be ameliorated by placement in an enriched environment during puberty (33), indicating that the neurobiological consequences of early - life adversity may be reversed, at least in part, through improvements to the environment.

ECD programmes can take many forms, including promotion of good health and nutrition, support for safe and stimulating environments, protection from risks such as violence or abandonment, parenting support and early learning experiences, media, preschools and community groups.4 Poverty is the key underlying cause of poor child development; children living in poverty are exposed to many negative influences, including poor physical environments, inadequate nutrition, parental stress and insufficient cognitive stimulation.5 Undernutrition can influence brain development directly by affecting brain structure and function, or indirectly via poor physical or motor development, in addition to other pathways.6 — 8 Exposure to multiple co-occurring risks most likely contributes to greater disparities in developmental trajectories among children with differential exposure.9 — 12 This paper focuses on associations between specific aspects of children's physical environments — access to improved water and sanitation (W&S)-- and childhood development as measured by performance on a test of receptive lExposure to multiple co-occurring risks most likely contributes to greater disparities in developmental trajectories among children with differential exposure.9 — 12 This paper focuses on associations between specific aspects of children's physical environments — access to improved water and sanitation (W&S)-- and childhood development as measured by performance on a test of receptive lexposure.9 — 12 This paper focuses on associations between specific aspects of children's physical environments — access to improved water and sanitation (W&S)-- and childhood development as measured by performance on a test of receptive language.

A harsh early environment was associated with an elevated flat cortisol trajectory across the stress tasks, suggesting that HPA axis functioning may have been compromised by recurring or chronic early life stress exposure.

3 THE EXTENT AND CHARACTER OF HEALTH INEQUALITIES IN THE EARLY YEARS 3.1 Key findings about health inequalities in the first four years 3.2 Introduction 3.3 Pregnancy, birth and the first three months 3.3.1 Risk factors and health outcomes in the early years 3.3.2 Inequalities in the early stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outEARLY YEARS 3.1 Key findings about health inequalities in the first four years 3.2 Introduction 3.3 Pregnancy, birth and the first three months 3.3.1 Risk factors and health outcomes in the early years 3.3.2 Inequalities in the early stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outearly years 3.3.2 Inequalities in the early stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outearly stages 3.4 Health measures in the first four years of life 3.5 Overview of health outcomes 3.5.1 Physical health 3.5.2 Problems reported by parents 3.5.3 Psychosocial health 3.5.4 Body mass index 3.6 Inequalities in health outcomes 3.6.1 Area deprivation 3.6.2 Household income 3.6.3 Socio - economic classification (NS - SEC) 3.6.4 Conclusion 3.7 Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative Exposure to risk factors likely to have an adverse impact on health 3.8 Inequalities in exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative exposure to risk factors for poor health outcomes 3.8.1 Area deprivation 3.8.2 Houshold income 3.8.3 Socio - economic classification (NS - SEC) 3.8.4 Conclusion 3.9 Summary measure of negative outcomes